ARHGDIG and CEP170P1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		ARHGDIG	CEP170P1
Description		Rho GDP dissociation inhibitor gamma	centrosomal protein 170 pseudogene 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Membrane Cytoplasmic Vesicle
	Molecular Function	GDP-dissociation Inhibitor Activity Rho GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding GTPase Regulator Activity	Protein Binding Identical Protein Binding
	Biological Process	Blastocyst Hatching Negative Regulation Of Cell Adhesion Rho Protein Signal Transduction Regulation Of Protein Localization
Pathways		RHOB GTPase cycle CDC42 GTPase cycle RHOH GTPase cycle RHOG GTPase cycle
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Body mass index ( 25760438)
Interacting Genes		12 interacting genes: AGTR1 BICRAL CDC42 CEP170P1 KXD1 MED10 RAC1 RHOA RHOB RHOG RHOH TACC3	17 interacting genes: ABI3 ARHGDIG C19orf25 C1orf216 CCDC120 CCDC146 CENPO CLHC1 HAUS1 KXD1 LMO1 LMO3 LMO4 RALYL RUNX1T1 SMARCE1 SSC5D
Entrez ID		398	645455
HPRD ID		04163
Ensembl ID		ENSG00000242173	ENSG00000298466
Uniprot IDs		F1T0H7 Q99819
PDB IDs
Enriched GO Terms of Interacting Partners?		Small GTPase-mediated Signal Transduction Actin Filament Organization GTPase Activity GTP Binding Rho Protein Signal Transduction Intracellular Signaling Cassette Supramolecular Fiber Organization Regulation Of Synapse Organization Wnt Signaling Pathway, Planar Cell Polarity Pathway Establishment Or Maintenance Of Cell Polarity Membrane Invagination Non-canonical Wnt Signaling Pathway Positive Regulation Of Stress Fiber Assembly Focal Adhesion Protein Kinase Binding Positive Regulation Of Actin Filament Bundle Assembly G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Postsynapse G Protein Activity Regulation Of Cytoskeleton Organization Thioesterase Binding Endothelial Tube Morphogenesis Regulation Of Stress Fiber Assembly Secretory Granule Membrane Regulation Of Modification Of Postsynaptic Structure Chemotaxis Establishment Of Epithelial Cell Apical/basal Polarity Intracellular Signal Transduction Regulation Of Actin Cytoskeleton Organization Locomotion Angiotensin-activated Signaling Pathway Regulation Of Modification Of Synaptic Structure Actin Cytoskeleton Organization GTP-dependent Protein Binding Establishment Of Apical/basal Cell Polarity Regulation Of Actin Filament-based Process Regulation Of Reactive Oxygen Species Metabolic Process Polarized Epithelial Cell Differentiation Regulation Of Postsynapse Organization Establishment Of Monopolar Cell Polarity Establishment Or Maintenance Of Monopolar Cell Polarity Positive Regulation Of Developmental Process Actin Filament-based Process Rac Protein Signal Transduction Positive Regulation Of Lamellipodium Assembly Nuclear Migration Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal Regulation Of Microtubule Cytoskeleton Organization Establishment Of Epithelial Cell Polarity Cerebral Cortex Cell Migration	DNA-binding Transcription Factor Binding
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