ATRIP and MOS

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ATRIP	MOS
Gene Name		ATR interacting protein	v-mos Moloney murine sarcoma viral oncogene homolog
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Cytoplasm
	Molecular Function	Protein Binding K63-linked Polyubiquitin Binding	Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity ATP Binding
	Biological Process	DNA Damage Checkpoint DNA Replication DNA Repair	MAPK Cascade Activation Of MAPKK Activity Activation Of MAPK Activity Meiotic Spindle Organization Chromatin Organization Regulation Of Meiosis Protein Autophosphorylation Establishment Of Meiotic Spindle Orientation Negative Regulation Of Metaphase/anaphase Transition Of Meiotic Cell Cycle
Pathways		G2/M DNA damage checkpoint G2/M Checkpoints Activation of ATR in response to replication stress Cell Cycle Checkpoints
Drugs
Diseases
GWAS			Height ( 18391951)
Protein-Protein Interactions		21 interactors: ATR BRCA1 C1orf94 CCDC28B CDC23 CDC6 CDK16 CEP164 CINP FAM156A FAM208B LNX1 METTL21A MID2 MOS MX2 POLR1C PRKDC RPA1 SCG2 SPRY2	28 interactors: ACTN2 ATRIP BMPR2 C17orf59 CALCOCO2 CCDC102B CCDC136 CCDC33 CCNDBP1 DYDC1 GFAP GOLGA2 HOMER3 HSPA1A KIFC3 KRT13 KRT15 KRT40 LZTS2 MID2 MTMR9 MYOD1 SEC24C SPERT SSX2IP TRAF1 TRIM27 USHBP1
Entrez ID		84126	4342
HPRD ID			01816
Ensembl ID		ENSG00000164053	ENSG00000172680
Uniprot IDs		Q8WXE1	P00540
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Cell Cycle Process DNA Repair Regulation Of Cell Cycle Double-strand Break Repair Via Homologous Recombination Recombinational Repair DNA Metabolic Process Cell Cycle Checkpoint Cellular Response To DNA Damage Stimulus DNA Replication Organelle Organization Response To Ionizing Radiation Double-strand Break Repair Negative Regulation Of DNA Replication Mitotic Cell Cycle Process Response To Gamma Radiation Mitotic Cell Cycle Negative Regulation Of Cell Cycle Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Process DNA Recombination Cellular Protein Modification Process Negative Regulation Of Protein Metabolic Process Regulation Of Cell Division Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Cellular Protein Metabolic Process Response To Stress Negative Regulation Of DNA Metabolic Process Cellular Response To Stress Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Regulation Of DNA Replication DNA Damage Checkpoint Regulation Of Cellular Response To Heat Cell Division Response To Radiation Positive Regulation Of Histone Methylation Cellular Protein Metabolic Process Positive Regulation Of Protein Modification Process Regulation Of Organelle Organization Regulation Of Chromosome Organization Cellular Metabolic Process Establishment Of Spindle Orientation Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Histone Methylation Protein Ubiquitination Chromosome Organization	Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Ion Transmembrane Transport Positive Regulation Of Schwann Cell Proliferation Response To Stress Negative Regulation Of Transmembrane Transport Protein Complex Assembly Regulation Of Viral Transcription Regulation Of Lung Blood Pressure Negative Regulation Of Interleukin-2 Secretion Myotube Differentiation Involved In Skeletal Muscle Regeneration Cellular Heat Acclimation Skeletal Muscle Fiber Adaptation Negative Regulation Of Chondrocyte Proliferation Myoblast Fate Determination Negative Regulation Of Viral Process Cytoskeleton Organization Regulation Of Signaling Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Localization Organelle Organization Negative Regulation Of Vasoconstriction Zonula Adherens Maintenance Negative Regulation Of Ion Transport
Tagcloud ?		biochemically canonical checkpoint checkpoints concert constitute damage damaged enlargement ercc1 excision exo1 exonuclease gap integrity mimetic minimum nucleotide repair rpa steps stranded tfiih topbp1 xpa xpc xpf xpg	cot densitometry erk2 hog immunoreactivities jnks kinases mapkapk2 mapks mek1 mekkl mkk3 mlk3 myocytes pak2 pakl phenomena probed proliferate proto raf1 rafb resist rsk1 rsk2 sekl tpl ventricle ventricles
Tagcloud (Difference) ?		biochemically canonical checkpoint checkpoints concert constitute damage damaged enlargement ercc1 excision exo1 exonuclease gap integrity mimetic minimum nucleotide repair rpa steps stranded tfiih topbp1 xpa xpc xpf xpg	cot densitometry erk2 hog immunoreactivities jnks kinases mapkapk2 mapks mek1 mekkl mkk3 mlk3 myocytes pak2 pakl phenomena probed proliferate proto raf1 rafb resist rsk1 rsk2 sekl tpl ventricle ventricles
Tagcloud (Intersection) ?