ATRIP and C1orf94

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ATRIP	C1orf94
Gene Name		ATR interacting protein	chromosome 1 open reading frame 94
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm
	Molecular Function	Protein Binding K63-linked Polyubiquitin Binding	Protein Binding
	Biological Process	DNA Damage Checkpoint DNA Replication DNA Repair
Pathways		G2/M DNA damage checkpoint G2/M Checkpoints Activation of ATR in response to replication stress Cell Cycle Checkpoints
Drugs
Diseases
GWAS			Epilepsy (generalized) ( 22949513)
Protein-Protein Interactions		21 interactors: ATR BRCA1 C1orf94 CCDC28B CDC23 CDC6 CDK16 CEP164 CINP FAM156A FAM208B LNX1 METTL21A MID2 MOS MX2 POLR1C PRKDC RPA1 SCG2 SPRY2	60 interactors: ACTN3 AES AKAP9 ATRIP ATXN1 BANP BOLA1 BOLL BYSL C1orf109 C6orf165 CARD9 CCHCR1 CCNJL CDKN2D DAB1 DAZAP2 DGCR6 DOK6 DTX2 FAM168A FAM46D GCC1 GORASP2 GRB2 GSE1 HNRNPF HOXA1 IPO11 KLHL32 LMO2 MAGED1 MAPK1IP1L MAPK9 MEIS2 MVP NFKBID NGB OAZ3 OIP5 PITX1 PLEKHB2 PRKAG1 PRR20A R3HDM2 RAD51D RBFOX1 RBFOX2 RBM47 RBPMS ROR2 SMAP2 TBX6 TNPO2 TXNDC9 UBQLN4 USO1 VENTX VPS37C YES1
Entrez ID		84126	84970
HPRD ID			11310
Ensembl ID		ENSG00000164053	ENSG00000142698
Uniprot IDs		Q8WXE1	Q6P1W5
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Cell Cycle Process DNA Repair Regulation Of Cell Cycle Double-strand Break Repair Via Homologous Recombination Recombinational Repair DNA Metabolic Process Cell Cycle Checkpoint Cellular Response To DNA Damage Stimulus DNA Replication Organelle Organization Response To Ionizing Radiation Double-strand Break Repair Negative Regulation Of DNA Replication Mitotic Cell Cycle Process Response To Gamma Radiation Mitotic Cell Cycle Negative Regulation Of Cell Cycle Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Process DNA Recombination Cellular Protein Modification Process Negative Regulation Of Protein Metabolic Process Regulation Of Cell Division Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Cellular Protein Metabolic Process Response To Stress Negative Regulation Of DNA Metabolic Process Cellular Response To Stress Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Regulation Of DNA Replication DNA Damage Checkpoint Regulation Of Cellular Response To Heat Cell Division Response To Radiation Positive Regulation Of Histone Methylation Cellular Protein Metabolic Process Positive Regulation Of Protein Modification Process Regulation Of Organelle Organization Regulation Of Chromosome Organization Cellular Metabolic Process Establishment Of Spindle Orientation Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Histone Methylation Protein Ubiquitination Chromosome Organization	Regulation Of Phosphorus Metabolic Process Regulation Of Phosphorylation Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Radial Glia Guided Migration Of Purkinje Cell Regulation Of Protein Metabolic Process Multicellular Organismal Development Positive Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Phosphorylation Cell Cycle Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Developmental Process Positive Regulation Of Cellular Biosynthetic Process Anatomical Structure Arrangement Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Splicing Cell Migration In Hindbrain Regulation Of RNA Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Phosphorylation Response To Radiation Negative Regulation Of Signaling Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cytoplasmic Transport Neuromuscular Process RNA Metabolic Process Positive Regulation Of Protein Metabolic Process Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Abducens Nerve Formation Optokinetic Behavior Regulation Of Erythrocyte Differentiation Response To Organic Substance Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Regulation Of Immune System Process Regulation Of Cellular Process Organ Development System Development Cell Differentiation Nucleobase-containing Compound Metabolic Process Regulation Of Kinase Activity Response To Light Stimulus Cellular Nitrogen Compound Metabolic Process Facial Nucleus Development Cerebellum Structural Organization Putrescine Transport Golgi Vesicle Docking
Tagcloud ?		biochemically canonical checkpoint checkpoints concert constitute damage damaged enlargement ercc1 excision exo1 exonuclease gap integrity mimetic minimum nucleotide repair rpa steps stranded tfiih topbp1 xpa xpc xpf xpg
Tagcloud (Difference) ?		biochemically canonical checkpoint checkpoints concert constitute damage damaged enlargement ercc1 excision exo1 exonuclease gap integrity mimetic minimum nucleotide repair rpa steps stranded tfiih topbp1 xpa xpc xpf xpg
Tagcloud (Intersection) ?