MOS and HOMEZ

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MOS	HOMEZ
Description		MOS proto-oncogene, serine/threonine kinase	homeobox and leucine zipper encoding
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Chromatin Nucleus Nucleoplasm Nucleolus Cytosol
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding
	Biological Process	MAPK Cascade Meiotic Spindle Organization Oocyte Maturation Chromatin Organization Signal Transduction Regulation Of Meiotic Nuclear Division Positive Regulation Of MAPK Cascade Establishment Of Meiotic Spindle Orientation Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Metaphase/anaphase Transition Of Meiotic Cell Cycle	Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Height ( 18391951) Refractive error ( 32231278)	Height ( 31562340) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 34021172) Mean platelet volume ( 32888494) Pulse pressure ( 27841878) Reticulocyte count ( 32888494) Serum alkaline phosphatase levels ( 33547301) Systolic blood pressure ( 27841878)
Interacting Genes		57 interacting genes: ACTN2 ASB6 ATRIP BICD2 BMPR2 BORCS6 CALCOCO2 CBY2 CCDC102B CCDC136 CCDC33 CCNDBP1 CFTR DYDC1 DZIP1 GFAP GOLGA2 GOLGA6A GOLGA6L9 GRAP2 HOMER3 HOMEZ HSPA1A IKZF1 KCTD6 KIFAP3 KIFC3 KRT13 KRT15 KRT27 KRT31 KRT33B KRT34 KRT40 KRTAP1-3 LZTS2 MAP2K2 MEOX2 MID2 MIPOL1 MTMR9 MTUS2 MYOD1 NBPF19 NOTCH2NLA PICK1 PPP2R5A PSTPIP1 RHOU SEC24C SSX2IP TP53BP2 TRAF1 TRAF2 TRIM27 USHBP1 ZBTB2	114 interacting genes: ACTR10 AEN ANKRD11 ANKRD2 ARHGAP9 ASB6 AXIN1 BIVM BYSL C2orf42 CBX8 CCDC13 CCDC187 CCHCR1 CCNK CDC7 CENPS CENPS-CORT CFAP206 CTNNA3 DEF6 DGCR6 DHX16 DNTTIP1 DRC4 EBF1 EIF4E2 ELOA ENKD1 FAM90A1 FARS2 GFAP GPANK1 GRB2 HOXC8 HSF2BP IL16 INO80B JAKMIP2 KIFC3 KPNA2 LENG1 LGALS4 LMO1 LMO3 LNX1 LRRC7 LSM4 MAD2L1BP MAFG MAPK1 MED18 MORF4L2 MOS MRPL11 NCK1 NCK2 NEIL2 NEK6 NXF1 OSGIN1 PARVG PHF1 PHF19 PIBF1 PIN1 PLEKHA7 POLDIP3 PRKAA1 PRKAA2 PRPF18 PSMA1 RASL10A RBM39 RNF8 RPGR RPL9 RPP25 RPS25 SCNM1 SDCBP SEC23A SH3RF2 SMARCB1 SMARCD1 SMYD1 SNRPB2 SUMO2 SUMO3 TARS2 TBC1D30 TCEA2 TCEANC TEAD4 TLE5 TRAF4 TSGA10IP TXK USF1 VEZF1 VPS9D1 ZBTB25 ZBTB7A ZMYND19 ZNF165 ZNF250 ZNF280C ZNF35 ZNF417 ZNF580 ZNF629 ZNF688 ZNF76 ZSCAN5B
Entrez ID		4342	57594
HPRD ID		01816	12167
Ensembl ID		ENSG00000172680	ENSG00000290292
Uniprot IDs		P00540	Q8IX15
PDB IDs			2ECC 2YS9
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Cytoskeleton Intermediate Filament Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament Structural Molecule Activity Supramolecular Fiber Organization Identical Protein Binding Cytosol Cytoskeleton Organization Protein Binding Epithelial Cell Differentiation Morphogenesis Of An Epithelium Organelle Organization Centrosome Tissue Morphogenesis Thioesterase Binding Cytoplasm Golgi Cis Cisterna	Nucleus Nucleoplasm Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Ciliary Basal Body Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Histone H2BS36 Kinase Activity [hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity Regulation Of Metabolic Process Nucleic Acid Metabolic Process Zinc Ion Binding Nuclear Speck Zonula Adherens Maintenance Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress Protein Localization To Lipid Droplet Microtubule Cytoskeleton Positive Regulation Of DNA Repair Centrosome Cytoskeletal Anchor Activity Positive Regulation Of Translation In Response To Endoplasmic Reticulum Stress DNA Binding Cellular Response To Stress Adherens Junction Maintenance Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Tubulin Deacetylation Negative Regulation Of Hepatocyte Apoptotic Process AMP-activated Protein Kinase Activity Positive Regulation Of DNA Metabolic Process Protein K6-linked Ubiquitination Regulation Of DNA-templated Transcription Elongation DNA Damage Response Regulation Of Translational Initiation Regulation Of Sister Chromatid Segregation Microtubule Cytoskeleton Organization Positive Regulation Of Translation In Response To Stress Histone H3K36me3 Reader Activity Regulation Of Tubulin Deacetylation Lipid Droplet Disassembly Macromolecule Metabolic Process Nucleobase-containing Compound Metabolic Process
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