ATRIP and METTL21A

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ATRIP	METTL21A
Gene Name		ATR interacting protein	methyltransferase like 21A
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Cytoplasm
	Molecular Function	Protein Binding K63-linked Polyubiquitin Binding	Protein Binding Protein-lysine N-methyltransferase Activity Hsp70 Protein Binding ATPase Binding
	Biological Process	DNA Damage Checkpoint DNA Replication DNA Repair	Protein Methylation Peptidyl-lysine Methylation Regulation Of ATPase Activity
Pathways		G2/M DNA damage checkpoint G2/M Checkpoints Activation of ATR in response to replication stress Cell Cycle Checkpoints
Drugs
Diseases
GWAS			Opioid sensitivity ( 23183491)
Protein-Protein Interactions		21 interactors: ATR BRCA1 C1orf94 CCDC28B CDC23 CDC6 CDK16 CEP164 CINP FAM156A FAM208B LNX1 METTL21A MID2 MOS MX2 POLR1C PRKDC RPA1 SCG2 SPRY2	5 interactors: ATRIP HSPA1A HSPA5 HSPA8 LNX1
Entrez ID		84126	151194
HPRD ID			14090
Ensembl ID		ENSG00000164053	ENSG00000144401
Uniprot IDs		Q8WXE1	H7BXH9 Q8WXB1
PDB IDs			4LEC
Enriched GO Terms of Interacting Partners?		Cell Cycle Cell Cycle Process DNA Repair Regulation Of Cell Cycle Double-strand Break Repair Via Homologous Recombination Recombinational Repair DNA Metabolic Process Cell Cycle Checkpoint Cellular Response To DNA Damage Stimulus DNA Replication Organelle Organization Response To Ionizing Radiation Double-strand Break Repair Negative Regulation Of DNA Replication Mitotic Cell Cycle Process Response To Gamma Radiation Mitotic Cell Cycle Negative Regulation Of Cell Cycle Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Process DNA Recombination Cellular Protein Modification Process Negative Regulation Of Protein Metabolic Process Regulation Of Cell Division Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Cellular Protein Metabolic Process Response To Stress Negative Regulation Of DNA Metabolic Process Cellular Response To Stress Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Regulation Of DNA Replication DNA Damage Checkpoint Regulation Of Cellular Response To Heat Cell Division Response To Radiation Positive Regulation Of Histone Methylation Cellular Protein Metabolic Process Positive Regulation Of Protein Modification Process Regulation Of Organelle Organization Regulation Of Chromosome Organization Cellular Metabolic Process Establishment Of Spindle Orientation Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Histone Methylation Protein Ubiquitination Chromosome Organization	Response To Unfolded Protein Protein Refolding Regulation Of Cellular Response To Heat Cellular Response To Heat Cellular Response To Stress Negative Regulation Of Fibril Organization Regulation Of Protein Folding In Endoplasmic Reticulum Response To Heat Cerebellum Structural Organization Cellular Heat Acclimation Cellular Macromolecule Catabolic Process Regulation Of Fibril Organization Response To Temperature Stimulus Regulation Of Protein Ubiquitination Clathrin Coat Disassembly Protein Folding Response To Stress Negative Regulation Of Inclusion Body Assembly ER Overload Response Maintenance Of Protein Localization In Endoplasmic Reticulum Catabolic Process Regulation Of Inclusion Body Assembly Response To External Stimulus Chaperone Mediated Protein Folding Requiring Cofactor Cellular Response To Antibiotic Positive Regulation Of MRNA Splicing, Via Spliceosome Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Erythrocyte Differentiation Anatomical Structure Arrangement Modification-dependent Protein Catabolic Process Secretion By Cell Cellular Protein Metabolic Process MRNA Metabolic Process Cellular Response To Toxic Substance Viral Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Response To Glucose Starvation Cellular Protein Catabolic Process Positive Regulation Of RNA Splicing Protein Catabolic Process Secretion Cerebellar Purkinje Cell Layer Development Regulation Of Erythrocyte Differentiation Substantia Nigra Development ER-associated Ubiquitin-dependent Protein Catabolic Process Toxin Transport Viral Entry Into Host Cell Cellular Response To Interleukin-4 Entry Into Host Cell Response To Biotic Stimulus
Tagcloud ?		biochemically canonical checkpoint checkpoints concert constitute damage damaged enlargement ercc1 excision exo1 exonuclease gap integrity mimetic minimum nucleotide repair rpa steps stranded tfiih topbp1 xpa xpc xpf xpg
Tagcloud (Difference) ?		biochemically canonical checkpoint checkpoints concert constitute damage damaged enlargement ercc1 excision exo1 exonuclease gap integrity mimetic minimum nucleotide repair rpa steps stranded tfiih topbp1 xpa xpc xpf xpg
Tagcloud (Intersection) ?