CBY1

Gene Name		chibby homolog 1 (Drosophila)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Trans-Golgi Network Cytosol Nuclear Speck
	Molecular Function	Protein Binding Beta-catenin Binding Identical Protein Binding
	Biological Process	Protein Localization Negative Regulation Of Wnt Signaling Pathway Fat Cell Differentiation Negative Regulation Of Transcription, DNA-templated Cardiac Muscle Cell Differentiation
Pathways		misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling TCF dependent signaling in response to WNT RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN Signaling by Wnt Signaling by WNT in cancer deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS
Protein-protein Interactions		8 interactors: AGTPBP1 CDK6 CFAP53 CLU CTNNB1 FAM92A1 NBPF11 TTC23L
Entrez ID		25776
HPRD ID		09676
Ensembl ID		ENSG00000100211
Uniprot IDs		Q9Y3M2
PDB IDs
Enriched GO Terms of Interacting Partners?		Glial Cell Proliferation Glial Cell Differentiation Gliogenesis Central Nervous System Development Telencephalon Development Forebrain Development T Cell Differentiation In Thymus Leukocyte Activation Negative Regulation Of Myeloid Cell Differentiation Neurogenesis Pancreas Development Regulation Of Fibroblast Proliferation Glial Cell Development Cell Dedifferentiation Positive Regulation Of Tau-protein Kinase Activity Regulation Of Neuronal Signal Transduction Microglial Cell Proliferation Cell Activation Regulation Of Osteoblast Differentiation Brain Development Head Development T Cell Differentiation Negative Regulation Of Mitotic Cell Cycle, Embryonic Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Neurofibrillary Tangle Assembly Schwann Cell Proliferation Cellular Response To Insulin-like Growth Factor Stimulus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Nervous System Development Eye Morphogenesis Regulation Of Myeloid Cell Differentiation Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Cardiac Outflow Tract Cell Proliferation Renal Inner Medulla Development Renal Outer Medulla Development Mesenchymal Cell Proliferation Involved In Lung Development Glial Cell Fate Determination Oviduct Development Regulation Of Centriole-centriole Cohesion Regulation Of Ossification Pallium Development Epithelial Cell Development Positive Regulation Of Determination Of Dorsal Identity Central Nervous System Myelin Maintenance C-terminal Protein Deglutamylation Lung Induction Embryonic Skeletal Limb Joint Morphogenesis Canonical Wnt Signaling Pathway Involved In Regulation Of Cell Proliferation Lymphocyte Differentiation Central Nervous System Vasculogenesis See more
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