CBY1

Description		chibby 1, beta catenin antagonist
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Trans-Golgi Network Centrosome Centriole Cytosol Cytoskeleton Cilium Nuclear Speck Motile Cilium Ciliary Basal Body Sperm Flagellum Cell Projection
	Molecular Function	Protein Binding Beta-catenin Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Intracellular Protein Localization Cell Projection Organization Cell Differentiation Negative Regulation Of Wnt Signaling Pathway Floor Plate Development Fat Cell Differentiation Negative Regulation Of DNA-templated Transcription Protein Homotetramerization Cardiac Muscle Cell Differentiation Canonical Wnt Signaling Pathway Cilium Assembly Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways		Deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS		Resting heart rate ( 27798624) Sleep duration ( 30846698)
Interacting Genes		18 interacting genes: AGTPBP1 CDK6 CFAP53 CIBAR1 CLU CTNNB1 DDIAS DZIP1L ENKD1 FAM161B GORASP2 LNX1 NBPF11 RALBP1 RASSF10 TNFAIP8L3 TSG101 TTC23L
Entrez ID		25776
HPRD ID		09676
Ensembl ID		ENSG00000100211
Uniprot IDs		Q9Y3M2
PDB IDs		4WRQ
Enriched GO Terms of Interacting Partners?		Cytoskeleton Spindle Pole Ciliary Basal Body Cilium Cilium Organization Centriole Cytoplasm Centrosome Organelle Assembly Microtubule Cytoskeleton Cilium Assembly Establishment Of Organelle Localization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Organelle Organization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Plasma Membrane Bounded Cell Projection Assembly Cell Projection Assembly Ciliary Transition Zone Cell Projection Cyclin D3-CDK6 Complex T Cell Differentiation In Thymus Cyclin D1-CDK6 Complex Cyclin D2-CDK6 Complex Negative Regulation Of Myeloid Leukocyte Differentiation FBXO Family Protein Binding Establishment Of Protein Localization To Vacuole Perinuclear Endoplasmic Reticulum Lumen Positive Regulation Of Neurofibrillary Tangle Assembly Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Neuronal Signal Transduction Cellular Component Assembly Mesenchymal Stem Cell Differentiation Positive Regulation Of Determination Of Dorsal Identity Negative Regulation Of Mitotic Cell Cycle, Embryonic Beta-catenin-ICAT Complex Positive Regulation Of Neural Precursor Cell Proliferation Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Glial Cell Fate Determination Renal Inner Medulla Development Scrib-APC-beta-catenin Complex Organelle Localization Renal Outer Medulla Development Renal Vesicle Formation Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation Positive Regulation Of Branching Involved In Lung Morphogenesis Neural Plate Development Extracellular Transport Positive Regulation Of Ubiquitin-dependent Endocytosis Doxorubicin Transport
Tagcloud ?