CBY1 and CFAP53

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CBY1	CFAP53
Gene Name		chibby homolog 1 (Drosophila)	cilia and flagella associated protein 53
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Trans-Golgi Network Cytosol Nuclear Speck	Cellular_component Cilium
	Molecular Function	Protein Binding Beta-catenin Binding Identical Protein Binding	Molecular_function
	Biological Process	Protein Localization Negative Regulation Of Wnt Signaling Pathway Fat Cell Differentiation Negative Regulation Of Transcription, DNA-templated Cardiac Muscle Cell Differentiation	Biological_process
Pathways		misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling TCF dependent signaling in response to WNT RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN Signaling by Wnt Signaling by WNT in cancer deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: AGTPBP1 CDK6 CFAP53 CLU CTNNB1 FAM92A1 NBPF11 TTC23L	9 interactors: APP CBY1 CCDC85B CEP70 HMG20A PNMA1 TEX11 TNIP1 TRIM23
Entrez ID		25776	220136
HPRD ID		09676	09958
Ensembl ID		ENSG00000100211	ENSG00000172361
Uniprot IDs		Q9Y3M2	Q96M91
PDB IDs
Enriched GO Terms of Interacting Partners?		Glial Cell Proliferation Glial Cell Differentiation Gliogenesis Central Nervous System Development Telencephalon Development Forebrain Development T Cell Differentiation In Thymus Leukocyte Activation Negative Regulation Of Myeloid Cell Differentiation Neurogenesis Pancreas Development Regulation Of Fibroblast Proliferation Glial Cell Development Cell Dedifferentiation Positive Regulation Of Tau-protein Kinase Activity Regulation Of Neuronal Signal Transduction Microglial Cell Proliferation Cell Activation Regulation Of Osteoblast Differentiation Brain Development Head Development T Cell Differentiation Negative Regulation Of Mitotic Cell Cycle, Embryonic Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Neurofibrillary Tangle Assembly Schwann Cell Proliferation Cellular Response To Insulin-like Growth Factor Stimulus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Nervous System Development Eye Morphogenesis Regulation Of Myeloid Cell Differentiation Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Cardiac Outflow Tract Cell Proliferation Renal Inner Medulla Development Renal Outer Medulla Development Mesenchymal Cell Proliferation Involved In Lung Development Glial Cell Fate Determination Oviduct Development Regulation Of Centriole-centriole Cohesion Regulation Of Ossification Pallium Development Epithelial Cell Development Positive Regulation Of Determination Of Dorsal Identity Central Nervous System Myelin Maintenance C-terminal Protein Deglutamylation Lung Induction Embryonic Skeletal Limb Joint Morphogenesis Canonical Wnt Signaling Pathway Involved In Regulation Of Cell Proliferation Lymphocyte Differentiation Central Nervous System Vasculogenesis	Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Negative Regulation Of Cellular Metabolic Process Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Meiotic Gene Conversion Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Cell Differentiation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Male Meiosis Chromosome Segregation Negative Regulation Of Neuron Differentiation Axon Choice Point Recognition
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