CBY1 and NBPF11

Number of citations of the paper that reports this interaction (PMID 20096688)
4

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid, pull down)

		CBY1	NBPF11
Gene Name		chibby homolog 1 (Drosophila)	neuroblastoma breakpoint family, member 11
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Trans-Golgi Network Cytosol Nuclear Speck	Cytoplasm
	Molecular Function	Protein Binding Beta-catenin Binding Identical Protein Binding
	Biological Process	Protein Localization Negative Regulation Of Wnt Signaling Pathway Fat Cell Differentiation Negative Regulation Of Transcription, DNA-templated Cardiac Muscle Cell Differentiation
Pathways		misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling TCF dependent signaling in response to WNT RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN Signaling by Wnt Signaling by WNT in cancer deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: AGTPBP1 CDK6 CFAP53 CLU CTNNB1 FAM92A1 NBPF11 TTC23L	2 interactors: CBY1 UBC
Entrez ID		25776	200030
HPRD ID		09676	14123
Ensembl ID		ENSG00000100211	ENSG00000152042
Uniprot IDs		Q9Y3M2	Q86T75 S4R413
PDB IDs
Enriched GO Terms of Interacting Partners?		Glial Cell Proliferation Glial Cell Differentiation Gliogenesis Central Nervous System Development Telencephalon Development Forebrain Development T Cell Differentiation In Thymus Leukocyte Activation Negative Regulation Of Myeloid Cell Differentiation Neurogenesis Pancreas Development Regulation Of Fibroblast Proliferation Glial Cell Development Cell Dedifferentiation Positive Regulation Of Tau-protein Kinase Activity Regulation Of Neuronal Signal Transduction Microglial Cell Proliferation Cell Activation Regulation Of Osteoblast Differentiation Brain Development Head Development T Cell Differentiation Negative Regulation Of Mitotic Cell Cycle, Embryonic Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Neurofibrillary Tangle Assembly Schwann Cell Proliferation Cellular Response To Insulin-like Growth Factor Stimulus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Nervous System Development Eye Morphogenesis Regulation Of Myeloid Cell Differentiation Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Cardiac Outflow Tract Cell Proliferation Renal Inner Medulla Development Renal Outer Medulla Development Mesenchymal Cell Proliferation Involved In Lung Development Glial Cell Fate Determination Oviduct Development Regulation Of Centriole-centriole Cohesion Regulation Of Ossification Pallium Development Epithelial Cell Development Positive Regulation Of Determination Of Dorsal Identity Central Nervous System Myelin Maintenance C-terminal Protein Deglutamylation Lung Induction Embryonic Skeletal Limb Joint Morphogenesis Canonical Wnt Signaling Pathway Involved In Regulation Of Cell Proliferation Lymphocyte Differentiation Central Nervous System Vasculogenesis	Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Regulation Of Canonical Wnt Signaling Pathway Regulation Of Wnt Signaling Pathway Viral Protein Processing Notch Receptor Processing Virion Assembly Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Glycogen Biosynthetic Process Intracellular Transport Of Virus Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Signaling Negative Regulation Of Gene Expression Cellular Polysaccharide Biosynthetic Process Negative Regulation Of Biosynthetic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Polysaccharide Biosynthetic Process Negative Regulation Of Type I Interferon Production Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of DNA-templated Transcription In Response To Stress DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Toll-like Receptor 2 Signaling Pathway Signal Transduction Involved In DNA Damage Checkpoint Toll-like Receptor 9 Signaling Pathway Signal Transduction Involved In Cell Cycle Checkpoint Glycogen Metabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Transferase Activity
Tagcloud ?			aminoterminal bait carboxyterminal chibby clusterin coil coiled copies copy documented duf1220 enigmatic evolution hybrid immunoprecipitated interacts macromolecular mutual nonetheless pinpointed primate remarkable repeat repressor topflash tri yeast
Tagcloud (Difference) ?			aminoterminal bait carboxyterminal chibby clusterin coil coiled copies copy documented duf1220 enigmatic evolution hybrid immunoprecipitated interacts macromolecular mutual nonetheless pinpointed primate remarkable repeat repressor topflash tri yeast
Tagcloud (Intersection) ?