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MAD1L1 and COIL
Number of citations of the paper that reports this interaction (PubMedID
16713569
)
0
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
MAD1L1
COIL
Description
mitotic arrest deficient 1 like 1
coilin
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Centromeric Region
Kinetochore
Spindle Pole
Nucleus
Nuclear Envelope
Chromosome
Cytoplasm
Centrosome
Spindle
Cytosol
Cytoskeleton
Nuclear Pore Nuclear Basket
Mitotic Spindle
Mitotic Spindle Pole
MAD1 Complex
Mitotic Spindle Assembly Checkpoint MAD1-MAD2 Complex
Fibrillar Center
Nucleus
Nucleoplasm
Nucleolus
Cajal Body
Membrane
Nuclear Body
Molecular Function
Protein Binding
Identical Protein Binding
Kinetochore Binding
Protein Binding
U1 SnRNA Binding
U2 SnRNA Binding
Identical Protein Binding
Biological Process
Mitotic Spindle Assembly Checkpoint Signaling
Negative Regulation Of T Cell Proliferation
Thymus Development
Cell Division
Attachment Of Mitotic Spindle Microtubules To Kinetochore
Regulation Of Metaphase Plate Congression
Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint
Regulation Of Mitotic Cell Cycle Phase Transition
Deactivation Of Mitotic Spindle Assembly Checkpoint
Spliceosomal SnRNP Assembly
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Adult body size (
32376654
)
Adverse response to drug (
30420678
)
Age at first birth (
34211149
)
Age at first sexual intercourse (
34211149
27089180
)
Alcohol consumption (drinks per week) (
30643258
)
Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) (
31835028
)
Anthropometric traits (multi-trait analysis) (
30166351
)
Anxiety (
31906708
)
Autism spectrum disorder or schizophrenia (
28540026
)
Bipolar disorder (
21926972
34002096
28115744
27329760
)
Bitter alcoholic beverage consumption (
31046077
)
Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) (
31374203
)
Coronary artery disease (
29212778
33020668
)
Dimensional psychopathology (Social) (
29496196
)
Disruptive behavior disorder and attention deficit hyperactivity disorder (
33495439
)
Gastroesophageal reflux disease (
34187846
31527586
)
General factor of neuroticism (
30867560
)
Gut microbiota relative abundance (Streptococcus) (
33208821
)
Hand grip strength (
29691431
)
Idiopathic pulmonary fibrosis (
31710517
)
Longevity (
20834067
)
Mosaic loss of chromosome Y (Y chromosome dosage) (
28346444
31624269
)
Myocardial infarction (
33532862
)
Number of sexual partners (
30643258
)
Platelet count (
32888494
)
Plateletcrit (
32888494
)
Prostate cancer (
29892016
)
Prostate cancer (advanced) (
29892016
)
Refractive error (
32231278
)
Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) (
26503814
)
Risk-taking tendency (4-domain principal component model) (
30643258
)
Rosacea symptom severity (
29771307
)
Schizophrenia (
30285260
22688191
28991256
23974872
29483656
)
Schizophrenia or bipolar disorder (
24280982
)
Schizophrenia, schizoaffective disorder or bipolar disorder (
24166486
)
Sepsis (28-day mortality) (
32592749
)
Sleep duration (short sleep) (
30846698
)
Smoking initiation (
33082346
)
Smoking status (ever vs never smokers) (
30643258
)
Superior frontal gyrus volume (
31530798
)
Superior temporal gyrus volume (
31530798
)
Systolic blood pressure (
30578418
)
Testicular germ cell tumor (
28604732
23666239
28604728
)
Vaginal microbiome composition (Shannon diversity index) (
32723796
)
Height (
18391951
)
Interacting Genes
63 interacting genes:
ALOX5
AMOTL2
ATG5
BIRC2
CAPN7
CCDC57
CCHCR1
CDC37
CDK18
CIMIP4
COIL
CWF19L2
DRC4
FAM131C
FAM90A1
FXR1
GPKOW
HAUS1
HDAC1
HDAC2
KIF9
LENG1
LGALSL
LMO1
LMO3
LNX1
MAD2L1
MAX
MFAP1
MLX
NDC80
NEBL
NEK2
NINL
NONO
NTAQ1
PIBF1
PML
PPP1R18
PSMA1
RNF8
SIN3A
SIN3B
SPATA18
SPATA2
SUPT5H
SYT17
SYT6
TCAF1
TEX11
TPM1
TPM3
TPR
TRIM29
TSC22D3
TSGA10
TSHZ3
TUBGCP4
UBC
UBTF
USP15
YJU2
ZSCAN32
84 interacting genes:
ACTN1
ACTN2
ACTN4
ADAMTS12
APP
ARMCX1
ATXN1
ATXN1L
BYSL
C1QBP
C9orf72
CCDC136
CCDC159
CCDC57
CCNE1
CDC23
CDK2
CEP70
CEP76
CSNK2B
CYB5R2
DHX16
DNAJA3
DRG1
DYNC2I2
ELOA2
FGF12
FHL5
FXR1
FXR2
GCC1
HSF2BP
KALRN
KAZN
KDM1A
KLC2
KLC4
KLHL42
KLHL8
KPNA3
LNX1
MAD1L1
MCRS1
MYO15B
MYO5B
NFU1
NIF3L1
NKAPD1
NOLC1
NTAQ1
NUDT18
OGT
PDE4D
PDLIM5
PIAS4
PICK1
PLEKHG4
PLOD3
POLR2L
POLR3C
PREPL
PRMT1
PRMT8
PSMA1
PSME3
PTS
SART3
SCYL1
SMN1
SNRPB
SNRPF
SNX6
SPANXN2
SRPK2
TAF9
TCAF1
TFCP2
TGS1
TSPYL2
XRCC5
XRCC6
ZBTB25
ZCCHC10
ZNF277
Entrez ID
8379
8161
HPRD ID
04065
02605
Ensembl ID
ENSG00000002822
ENSG00000121058
Uniprot IDs
Q9Y6D9
P38432
PDB IDs
1GO4
4DZO
7B1F
7B1H
7B1J
Enriched GO Terms of Interacting Partners
?
Cytoplasm
Sin3-type Complex
Nucleoplasm
Protein Binding
Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint
Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides
Chromatin Binding
Protein Lysine Delactylase Activity
Fungiform Papilla Formation
Positive Regulation Of Cell Cycle Checkpoint
Spindle Assembly
Nuclear Chromosome Segregation
Protein Decrotonylase Activity
Histone Decrotonylase Activity
Muscle Thin Filament Tropomyosin
Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint
Microtubule Cytoskeleton Organization
Hair Follicle Placode Formation
Negative Regulation Of Stem Cell Population Maintenance
Membraneless Organelle Assembly
Mitotic Spindle Assembly Checkpoint Signaling
Regulation Of Mitotic Cell Cycle
Cellular Response To Dopamine
Negative Regulation Of Mitotic Metaphase/anaphase Transition
Negative Regulation Of Chromosome Organization
Intracellular Membraneless Organelle
Negative Regulation Of RNA Metabolic Process
Response To Dopamine
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Mitotic Sister Chromatid Segregation
Stress Fiber
Centrosome
Cytoskeleton
Negative Regulation Of Mitotic Nuclear Division
Sister Chromatid Segregation
Histone Deacetylase Complex
Histone Deacetylase Activity, Hydrolytic Mechanism
Kinetochore
Spindle Organization
Podosome
Nuclear Pore Complex Assembly
Microtubule-based Process
Regulation Of Defense Response
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
DNA-binding Transcription Factor Binding
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Positive Regulation Of Stem Cell Population Maintenance
Calcium-dependent Phospholipid Binding
Protein Lysine Deacetylase Activity
Cytoplasm
Cytosol
Nucleoplasm
Macromolecule Metabolic Process
Nucleic Acid Metabolic Process
Spliceosomal SnRNP Assembly
Nucleus
Cellular Component Assembly
Nucleobase-containing Compound Metabolic Process
Protein-RNA Complex Assembly
7-methylguanosine Cap Hypermethylation
Cajal Body
Protein Binding
Methylosome
RNA Metabolic Process
Transmembrane Transporter Binding
Cytoskeleton
Z Disc
Pseudopodium
Negative Regulation Of DNA Metabolic Process
Cyclin E1-CDK2 Complex
DNA End Binding
Ku70:Ku80 Complex
SMN-Sm Protein Complex
Small Nuclear Ribonucleoprotein Complex
Regulation Of Translation At Presynapse, Modulating Synaptic Transmission
Spliceosomal Complex Assembly
Regulation Of Protein Metabolic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Postsynapse
Telomere Maintenance
POZ Domain Binding
Nucleolus
Main Axon
DNA-dependent Protein Kinase Complex
Protein-arginine Omega-N Monomethyltransferase Activity
Peptidyl-arginine Methylation
Regulation Of RNA Metabolic Process
Macromolecule Methylation
DNA-templated Transcription
Identical Protein Binding
Regulation Of Long-term Neuronal Synaptic Plasticity
Protein Modification Process
Platelet Alpha Granule Lumen
Protein-containing Complex Assembly
Negative Regulation Of Double-strand Break Repair Via Homologous Recombination
Telomeric DNA Binding
Cellular Response To Gamma Radiation
RNA Splicing
Telomere Organization
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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