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COIL and POLR2L
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
COIL
POLR2L
Gene Name
coilin
polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cajal Body
Membrane
Nucleus
Nucleoplasm
DNA-directed RNA Polymerase II, Core Complex
DNA-directed RNA Polymerase III Complex
DNA-directed RNA Polymerase I Complex
Cytosol
Molecular Function
Protein Binding
Protein C-terminus Binding
Identical Protein Binding
RNA Polymerase I Activity
RNA Polymerase II Activity
RNA Polymerase III Activity
DNA Binding
DNA-directed RNA Polymerase Activity
Zinc Ion Binding
Biological Process
MRNA Splicing, Via Spliceosome
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Nucleotide-excision Repair
Regulation Of Transcription From RNA Polymerase I Promoter
Transcription From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Transcription From RNA Polymerase III Promoter
Transcription Elongation From RNA Polymerase III Promoter
Termination Of RNA Polymerase III Transcription
RNA Splicing
Gene Expression
Viral Process
Positive Regulation Of Type I Interferon Production
PiRNA Metabolic Process
Somatic Stem Cell Maintenance
Regulation Of Gene Expression, Epigenetic
Innate Immune Response
Negative Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Viral Transcription
Pathways
RNA Polymerase II Promoter Escape
Formation of HIV-1 elongation complex containing HIV-1 Tat
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Chain Elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
Regulatory RNA pathways
Tat-mediated elongation of the HIV-1 transcript
Tat-mediated HIV elongation arrest and recovery
Formation of transcription-coupled NER (TC-NER) repair complex
Dual incision reaction in TC-NER
Influenza Life Cycle
RNA Polymerase III Transcription Termination
HIV elongation arrest and recovery
NoRC negatively regulates rRNA expression
Influenza Viral RNA Transcription and Replication
RNA Polymerase III Chain Elongation
RNA Polymerase III Transcription
RNA Polymerase III Transcription Initiation From Type 1 Promoter
mRNA Splicing - Minor Pathway
mRNA Splicing - Major Pathway
MicroRNA (miRNA) biogenesis
Influenza Infection
Pausing and recovery of Tat-mediated HIV elongation
Late Phase of HIV Life Cycle
RNA Polymerase III Transcription Initiation From Type 2 Promoter
Formation of RNA Pol II elongation complex
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Polymerase III Abortive And Retractive Initiation
Transcription of the HIV genome
Nucleotide Excision Repair
PIWI-interacting RNA (piRNA) biogenesis
mRNA Splicing
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Polymerase II Transcription
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Clearance
HIV Infection
Formation of the Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE
RNA Polymerase II Pre-transcription Events
HIV Transcription Initiation
HIV Life Cycle
RNA Pol II CTD phosphorylation and interaction with CE
Transcriptional regulation of pluripotent stem cells
RNA Polymerase II HIV Promoter Escape
HIV Transcription Elongation
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
Innate Immune System
RNA Polymerase III Transcription Initiation
Transcriptional regulation by small RNAs
Processing of Capped Intron-Containing Pre-mRNA
mRNA Capping
RNA Polymerase I Transcription
RNA Polymerase I Promoter Escape
RNA Polymerase I Transcription Termination
Cytosolic sensors of pathogen-associated DNA
Epigenetic regulation of gene expression
Negative epigenetic regulation of rRNA expression
Transcription-coupled NER (TC-NER)
Formation of HIV elongation complex in the absence of HIV Tat
Pausing and recovery of HIV elongation
Formation of the HIV-1 Early Elongation Complex
Viral Messenger RNA Synthesis
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Height (
18391951
)
Protein-Protein Interactions
70 interactors:
ACTN1
ACTN2
ACTN4
APP
ARMCX1
ATXN1
ATXN1L
BYSL
C1QBP
CCDC136
CCDC159
CCNE1
CDC23
CDK2
CEP70
CEP76
CSNK2B
CYB5R2
DHX16
DNAJA3
DRG1
FGF12
FHL5
FXR2
GCC1
KALRN
KAZN
KLC2
KLC4
KLHL42
KLHL8
KPNA3
LNX1
MAD1L1
MFAP1
MYO5B
NIF3L1
NOLC1
NUDT18
PDE4D
PDLIM5
PIAS4
PICK1
PLEKHG4
POLR2L
PREPL
PRMT1
PRMT8
PSMA1
PSME3
PTS
SART3
SCYL1
SMN1
SNRPB
SNRPF
SNX6
TAF9
TCAF1
TCEB3B
TFCP2
TGS1
TSPYL2
WDR34
WDYHV1
XRCC5
XRCC6
ZBTB25
ZCCHC10
ZNF277
23 interactors:
BANP
CCDC85B
CHEK2
COIL
EXOSC5
L3MBTL3
NFKBIB
NOV
PHC2
POLR2A
POLR2B
POLR2C
POLR2D
POLR2E
POLR2G
POLR2H
REL
RPAP1
SNX7
SPAG5
THAP1
TP53BP2
ZBTB14
Entrez ID
8161
5441
HPRD ID
02605
01155
Ensembl ID
ENSG00000121058
ENSG00000177700
Uniprot IDs
P38432
P62875
PDB IDs
Enriched GO Terms of Interacting Partners
?
Cellular Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Spliceosomal SnRNP Assembly
Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
RNA Metabolic Process
Regulation Of Metabolic Process
MRNA Processing
Ribonucleoprotein Complex Biogenesis
RNA Processing
Regulation Of Nitrogen Compound Metabolic Process
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Mitotic Cell Cycle
RNA Splicing
Gene Expression
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Ribonucleoprotein Complex Assembly
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Cellular Hyperosmotic Salinity Response
Protein Localization To Tight Junction
Regulation Of Cellular Protein Metabolic Process
Mitotic Cell Cycle Process
Regulation Of RNA Metabolic Process
MRNA Metabolic Process
Transcription, DNA-templated
Regulation Of Mitotic Cell Cycle Phase Transition
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Cellular Metabolic Process
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Regulation Of Cell Cycle Phase Transition
RNA Biosynthetic Process
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Cell Cycle Process
Regulation Of Protein Metabolic Process
Platelet Degranulation
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cellular Macromolecular Complex Assembly
Negative Regulation Of Cellular Protein Metabolic Process
Mitotic Cell Cycle Checkpoint
DNA Damage Response, Signal Transduction By P53 Class Mediator
Regulation Of Gene Expression
Cellular Response To X-ray
Regulation Of Ubiquitin-protein Transferase Activity
Viral Process
Cellular Component Assembly
7-methylguanosine MRNA Capping
PiRNA Metabolic Process
7-methylguanosine RNA Capping
Transcription-coupled Nucleotide-excision Repair
Positive Regulation Of Viral Transcription
Transcription Elongation From RNA Polymerase II Promoter
Somatic Stem Cell Maintenance
Regulation Of Viral Transcription
Positive Regulation Of Viral Process
DNA-templated Transcription, Elongation
Nucleotide-excision Repair
Transcription, DNA-templated
RNA Biosynthetic Process
RNA Metabolic Process
Stem Cell Maintenance
Regulation Of Viral Process
Gene Expression
Transcription Initiation From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Stem Cell Development
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
NcRNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Stem Cell Differentiation
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
MRNA Metabolic Process
RNA Splicing
Cellular Nitrogen Compound Metabolic Process
DNA Repair
Transcription From RNA Polymerase II Promoter
MRNA Processing
Nitrogen Compound Metabolic Process
Biosynthetic Process
Negative Regulation Of Cell Differentiation
DNA Metabolic Process
Regulation Of Gene Expression
Regulation Of RNA Biosynthetic Process
Viral Process
Cellular Response To DNA Damage Stimulus
Regulation Of RNA Metabolic Process
RNA Processing
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Positive Regulation Of Cellular Biosynthetic Process
Cell Development
Tagcloud
?
augment
augments
bait
cbp
coactivator
coiled
enhances
except
hybrid
ifngamma
instead
interactor
interacts
interestingly
intrinsic
lacks
myc
nmi
potentiate
recruitment
reveal
screen
stat
stat1
stat2
stat5
stat5b
stats
yeast
Tagcloud (Difference)
?
augment
augments
bait
cbp
coactivator
coiled
enhances
except
hybrid
ifngamma
instead
interactor
interacts
interestingly
intrinsic
lacks
myc
nmi
potentiate
recruitment
reveal
screen
stat
stat1
stat2
stat5
stat5b
stats
yeast
Tagcloud (Intersection)
?