COIL and CEP76

Number of citations of the paper that reports this interaction (PubMedID 16713569)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		COIL	CEP76
Description		coilin	centrosomal protein 76
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Nucleolus Cajal Body Membrane Nuclear Body	Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Protein-containing Complex
	Molecular Function	Protein Binding U1 SnRNA Binding U2 SnRNA Binding Identical Protein Binding	Protein Binding
	Biological Process	Spliceosomal SnRNP Assembly	Regulation Of Centriole Replication
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Height ( 18391951)
Interacting Genes		84 interacting genes: ACTN1 ACTN2 ACTN4 ADAMTS12 APP ARMCX1 ATXN1 ATXN1L BYSL C1QBP C9orf72 CCDC136 CCDC159 CCDC57 CCNE1 CDC23 CDK2 CEP70 CEP76 CSNK2B CYB5R2 DHX16 DNAJA3 DRG1 DYNC2I2 ELOA2 FGF12 FHL5 FXR1 FXR2 GCC1 HSF2BP KALRN KAZN KDM1A KLC2 KLC4 KLHL42 KLHL8 KPNA3 LNX1 MAD1L1 MCRS1 MYO15B MYO5B NFU1 NIF3L1 NKAPD1 NOLC1 NTAQ1 NUDT18 OGT PDE4D PDLIM5 PIAS4 PICK1 PLEKHG4 PLOD3 POLR2L POLR3C PREPL PRMT1 PRMT8 PSMA1 PSME3 PTS SART3 SCYL1 SMN1 SNRPB SNRPF SNX6 SPANXN2 SRPK2 TAF9 TCAF1 TFCP2 TGS1 TSPYL2 XRCC5 XRCC6 ZBTB25 ZCCHC10 ZNF277	105 interacting genes: AKAP7 AKT1 ANKRD36 ASH2L BANP C22orf39 CABP5 CACNB3 CAPN3 CAVIN3 CCDC92 CCNK CDK18 CENPI CIRSR COIL CRYBA4 CSNK1G1 CUTC CWF19L2 DCTD DDX6 DEAF1 DMTN DVL3 DZIP1L EAF1 EIF1AD EP400P1 ERCC3 FAM90A1 GDAP2 GFAP GORASP2 HACL2 HSF2 HSPB7 IQUB KDM1A KDM4D KIAA1143 KIFBP KLHDC4 L3MBTL2 LATS1 LNX1 MAGEA11 MBD3 MFAP1 MISP MLH1 MYOZ1 NEK6 NFYC NHLRC2 NME5 PAICS PARD6B PATZ1 PDGFRB PDRG1 PDZD4 PDZD7 PIN1 PKP1 PLA2G6 PLCB1 POM121 RADIL RALGPS1 RBM41 RIPPLY3 RNF128 RPL9 SALL2 SCNM1 SH2D4A SINHCAF SMG9 SPG21 STK26 SUOX TBC1D27P TCEA2 TCEANC TCF19 TFAP2D THRA TOB2 TSPOAP1 TSSC4 TTC21A TTLL10 TUFT1 TXNDC9 VEZF1 WDFY3 YY1 ZBTB24 ZBTB4 ZMAT2 ZNF185 ZNF653 ZNF76 ZNF85
Entrez ID		8161	79959
HPRD ID		02605	12694
Ensembl ID		ENSG00000121058	ENSG00000101624
Uniprot IDs		P38432	B4DP81 Q8TAP6
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoplasm Cytosol Nucleoplasm Macromolecule Metabolic Process Nucleic Acid Metabolic Process Spliceosomal SnRNP Assembly Nucleus Cellular Component Assembly Nucleobase-containing Compound Metabolic Process Protein-RNA Complex Assembly 7-methylguanosine Cap Hypermethylation Cajal Body Protein Binding Methylosome RNA Metabolic Process Transmembrane Transporter Binding Cytoskeleton Z Disc Pseudopodium Negative Regulation Of DNA Metabolic Process Cyclin E1-CDK2 Complex DNA End Binding Ku70:Ku80 Complex SMN-Sm Protein Complex Small Nuclear Ribonucleoprotein Complex Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Spliceosomal Complex Assembly Regulation Of Protein Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Postsynapse Telomere Maintenance POZ Domain Binding Nucleolus Main Axon DNA-dependent Protein Kinase Complex Protein-arginine Omega-N Monomethyltransferase Activity Peptidyl-arginine Methylation Regulation Of RNA Metabolic Process Macromolecule Methylation DNA-templated Transcription Identical Protein Binding Regulation Of Long-term Neuronal Synaptic Plasticity Protein Modification Process Platelet Alpha Granule Lumen Protein-containing Complex Assembly Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Telomeric DNA Binding Cellular Response To Gamma Radiation RNA Splicing Telomere Organization	Protein Binding Nucleus
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