COIL and PREPL

Number of citations of the paper that reports this interaction (PubMedID 16713569)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		COIL	PREPL
Description		coilin	prolyl endopeptidase like
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Nucleolus Cajal Body Membrane Nuclear Body	Nucleus Cytoplasm Mitochondrion Golgi Apparatus Trans-Golgi Network Cytosol Cytoskeleton
	Molecular Function	Protein Binding U1 SnRNA Binding U2 SnRNA Binding Identical Protein Binding	Serine-type Endopeptidase Activity Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity
	Biological Process	Spliceosomal SnRNP Assembly	Proteolysis Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport Regulation Of Synaptic Vesicle Exocytosis
Pathways
Drugs
Diseases
GWAS		Height ( 18391951)	antipsychotic drug dosage in schizophrenia or schizoaffective disorder ( 26821981) Ceramide levels (C24:0) ( 32489964) Daytime nap ( 33568662) Femur bone mineral density x serum urate levels interaction ( 34046847) Refractive error ( 32231278)
Interacting Genes		84 interacting genes: ACTN1 ACTN2 ACTN4 ADAMTS12 APP ARMCX1 ATXN1 ATXN1L BYSL C1QBP C9orf72 CCDC136 CCDC159 CCDC57 CCNE1 CDC23 CDK2 CEP70 CEP76 CSNK2B CYB5R2 DHX16 DNAJA3 DRG1 DYNC2I2 ELOA2 FGF12 FHL5 FXR1 FXR2 GCC1 HSF2BP KALRN KAZN KDM1A KLC2 KLC4 KLHL42 KLHL8 KPNA3 LNX1 MAD1L1 MCRS1 MYO15B MYO5B NFU1 NIF3L1 NKAPD1 NOLC1 NTAQ1 NUDT18 OGT PDE4D PDLIM5 PIAS4 PICK1 PLEKHG4 PLOD3 POLR2L POLR3C PREPL PRMT1 PRMT8 PSMA1 PSME3 PTS SART3 SCYL1 SMN1 SNRPB SNRPF SNX6 SPANXN2 SRPK2 TAF9 TCAF1 TFCP2 TGS1 TSPYL2 XRCC5 XRCC6 ZBTB25 ZCCHC10 ZNF277	3 interacting genes: CAPN3 COIL RIPK4
Entrez ID		8161	9581
HPRD ID		02605	17189
Ensembl ID		ENSG00000121058	ENSG00000138078
Uniprot IDs		P38432	Q4J6C6
PDB IDs			7OBM 8RFB
Enriched GO Terms of Interacting Partners?		Cytoplasm Cytosol Nucleoplasm Macromolecule Metabolic Process Nucleic Acid Metabolic Process Spliceosomal SnRNP Assembly Nucleus Cellular Component Assembly Nucleobase-containing Compound Metabolic Process Protein-RNA Complex Assembly 7-methylguanosine Cap Hypermethylation Cajal Body Protein Binding Methylosome RNA Metabolic Process Transmembrane Transporter Binding Cytoskeleton Z Disc Pseudopodium Negative Regulation Of DNA Metabolic Process Cyclin E1-CDK2 Complex DNA End Binding Ku70:Ku80 Complex SMN-Sm Protein Complex Small Nuclear Ribonucleoprotein Complex Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Spliceosomal Complex Assembly Regulation Of Protein Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Postsynapse Telomere Maintenance POZ Domain Binding Nucleolus Main Axon DNA-dependent Protein Kinase Complex Protein-arginine Omega-N Monomethyltransferase Activity Peptidyl-arginine Methylation Regulation Of RNA Metabolic Process Macromolecule Methylation DNA-templated Transcription Identical Protein Binding Regulation Of Long-term Neuronal Synaptic Plasticity Protein Modification Process Platelet Alpha Granule Lumen Protein-containing Complex Assembly Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Telomeric DNA Binding Cellular Response To Gamma Radiation RNA Splicing Telomere Organization	Calcium-dependent Self Proteolysis Ligase Regulator Activity Positive Regulation Of Satellite Cell Activation Involved In Skeletal Muscle Regeneration Regulation Of Satellite Cell Activation Involved In Skeletal Muscle Regeneration Negative Regulation Of Protein Sumoylation Self Proteolysis Regulation Of Skeletal Muscle Tissue Regeneration Cellular Response To Salt Stress Positive Regulation Of Skeletal Muscle Tissue Regeneration Sodium Ion Binding G1 To G0 Transition Involved In Cell Differentiation U1 SnRNA Binding U2 SnRNA Binding Calcium-dependent Cysteine-type Endopeptidase Activity Titin Binding G1 To G0 Transition Response To Salt Stress Regulation Of Protein Sumoylation
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