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HIST1H3A and HIST2H4A
Number of citations of the paper that reports this interaction (PMID
8598932
)
52
Data Source:
BioGRID
(pull down)
HIST1H3A
HIST2H4A
Gene Name
histone cluster 1, H3a
histone cluster 2, H4a
Image
Gene Ontology Annotations
Cellular Component
Nuclear Chromosome
Nucleosome
Extracellular Region
Nucleus
Nucleoplasm
Membrane
Protein Complex
Extracellular Vesicular Exosome
Nuclear Chromosome
Nucleosome
Extracellular Region
Nucleus
Nucleoplasm
Membrane
Protein Complex
Extracellular Vesicular Exosome
Molecular Function
DNA Binding
Protein Binding
Protein Heterodimerization Activity
DNA Binding
Protein Binding
Histone Demethylase Activity (H4-K20 Specific)
Poly(A) RNA Binding
Protein Heterodimerization Activity
Biological Process
Chromatin Silencing At RDNA
Chromatin Organization
DNA Replication-dependent Nucleosome Assembly
Blood Coagulation
Gene Expression
DNA Methylation On Cytosine
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Gene Expression, Epigenetic
Regulation Of Gene Silencing
Chromatin Silencing At RDNA
Mitotic Cell Cycle
Telomere Maintenance
Chromatin Organization
Nucleosome Assembly
DNA Replication-dependent Nucleosome Assembly
DNA Replication-independent Nucleosome Assembly
Gene Expression
DNA Methylation On Cytosine
CENP-A Containing Nucleosome Assembly
Histone H4-K20 Demethylation
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Megakaryocyte Differentiation
Negative Regulation Of Gene Expression, Epigenetic
Pathways
RNA Polymerase I Chain Elongation
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
Mitotic Prophase
PKMTs methylate histone lysines
Regulatory RNA pathways
RNA Polymerase I Promoter Clearance
HDMs demethylate histones
Cellular Senescence
Signaling by Wnt
HATs acetylate histones
M Phase
Amyloids
NoRC negatively regulates rRNA expression
RNF mutants show enhanced WNT signaling and proliferation
XAV939 inhibits tankyrase, stabilizing AXIN
DNA methylation
Transcriptional regulation by small RNAs
Meiotic recombination
HDACs deacetylate histones
Chromatin organization
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
RNA Polymerase I Transcription
formation of the beta-catenin:TCF transactivating complex
Epigenetic regulation of gene expression
Senescence-Associated Secretory Phenotype (SASP)
Negative epigenetic regulation of rRNA expression
Factors involved in megakaryocyte development and platelet production
PRC2 methylates histones and DNA
Cell Cycle, Mitotic
RMTs methylate histone arginines
Chromatin modifying enzymes
Oxidative Stress Induced Senescence
TCF dependent signaling in response to WNT
RNA Polymerase I Promoter Opening
SIRT1 negatively regulates rRNA Expression
Signaling by WNT in cancer
Condensation of Prophase Chromosomes
RNA Polymerase I Chain Elongation
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
Mitotic Prophase
PKMTs methylate histone lysines
Regulatory RNA pathways
RNA Polymerase I Promoter Clearance
Deposition of new CENPA-containing nucleosomes at the centromere
HDMs demethylate histones
Cellular Senescence
Signaling by Wnt
HATs acetylate histones
M Phase
Amyloids
NoRC negatively regulates rRNA expression
Packaging Of Telomere Ends
Telomere Maintenance
Nucleosome assembly
RNF mutants show enhanced WNT signaling and proliferation
XAV939 inhibits tankyrase, stabilizing AXIN
DNA methylation
Transcriptional regulation by small RNAs
Meiotic recombination
DNA Damage/Telomere Stress Induced Senescence
Chromosome Maintenance
HDACs deacetylate histones
Chromatin organization
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
RNA Polymerase I Transcription
formation of the beta-catenin:TCF transactivating complex
Meiotic synapsis
Epigenetic regulation of gene expression
Senescence-Associated Secretory Phenotype (SASP)
Negative epigenetic regulation of rRNA expression
PRC2 methylates histones and DNA
Cell Cycle, Mitotic
RMTs methylate histone arginines
Chromatin modifying enzymes
Oxidative Stress Induced Senescence
TCF dependent signaling in response to WNT
RNA Polymerase I Promoter Opening
SIRT1 negatively regulates rRNA Expression
Signaling by WNT in cancer
Condensation of Prophase Chromosomes
Drugs
Diseases
GWAS
Protein-Protein Interactions
117 interactors:
AIRE
AKT2
ALL1
ANP32A
ASH1L
ASH2L
ATRX
ATXN1
ATXN7
AURKB
AURKC
BAZ1B
CALCOCO1
CARM1
CBX1
CBX3
CHD4
COPS2
CREBBP
CTCFL
CUL4A
DDB1
DNMT3A
DPF2
DYRK1A
EED
EHMT1
EHMT2
EID1
EP300
ERCC6
ESCO1
EZH2
FBLIM1
GATAD2A
GATAD2B
GRIP1
GSG2
HDAC2
HDAC8
HIST1H4A
HIST2H2AC
HIST2H4A
HNF1B
ING4
KAT2A
KAT2B
KAT5
KAT6A
KAT7
KDM1A
KDM2B
KDM4A
KDM4C
KDM6A
KDM6B
KMT2A
KMT2B
KMT2C
L3MBTL2
LBR
LOXL2
MEN1
MSL3
MYOD1
NCOR1
NPM1
NR1H4
PAF1
PAK1
PARP10
PAXIP1
PBRM1
PHF1
PHF20
PHF8
PRDM2
PRKCA
PRKCB
PRMT1
PRMT5
PRMT7
RAD51B
RAG1
RCC1
RPS6KA3
SET
SETD1A
SETD1B
SETD2
SETD7
SETDB1
SIRT1
SIRT2
SIRT7
SMARCA2
SMARCA4
SMARCA5
SNAI1
SSRP1
SUV39H1
TAF1
TAF15
TAF1A
TAF1B
THAP7
TRIM24
TRIM33
TSSK6
UHRF1
UHRF2
VPRBP
WHSC1
WWC1
YWHAB
YWHAG
YWHAZ
27 interactors:
ATAD2
BRD4
BRDT
DNMT3L
EP300
HAT1
HIST1H3A
HIST2H2AC
KAT2A
KAT5
LBR
NAP1L4
PRMT1
PTMA
RAD51B
RBBP4
RNF20
RPS6KA5
SET
TAF15
TBL1X
TBL1XR1
TP53BP1
UBC
UCHL5
UHRF1
YWHAQ
Entrez ID
8350
8370
HPRD ID
04155
11821
Ensembl ID
ENSG00000198366
ENSG00000183941
Uniprot IDs
P68431
B2R4R0
P62805
PDB IDs
1CS9
1CT6
1Q3L
2B2T
2B2U
2B2V
2B2W
2C1J
2C1N
2CV5
2KWJ
2KWK
2L75
2LBM
2M0O
2RI7
2UXN
3A1B
3AFA
3AVR
3AYW
3AZE
3AZF
3AZG
3AZH
3AZI
3AZJ
3AZK
3AZL
3AZM
3AZN
3B95
3KMT
3KQI
3LQI
3LQJ
3O34
3O35
3O37
3RIG
3RIY
3U4S
3U5N
3U5O
3U5P
3UEE
3UEF
3UIG
3UII
3UIK
3V43
3W96
3W97
3W98
3W99
3ZG6
3ZVY
4A0J
4A0N
4A7J
4BD3
4F4U
4F56
4FWF
4HON
4I51
2BQZ
2CV5
2KWN
2KWO
2LVM
2QQS
2RNY
2RS9
3A6N
3AFA
3AN2
3AV1
3AV2
3AYW
3AZE
3AZF
3AZG
3AZH
3AZI
3AZJ
3AZK
3AZL
3AZM
3AZN
3CFS
3CFV
3F9W
3F9X
3F9Y
3F9Z
3NQJ
3NQU
3O36
3QZS
3QZT
3QZV
3R45
3UVW
3UVX
3UVY
3UW9
3W96
3W97
3W98
3W99
4GQB
4H9N
4H9O
4H9P
4H9Q
4H9R
4H9S
4HGA
Enriched GO Terms of Interacting Partners
?
Chromatin Modification
Chromatin Organization
Histone Modification
Chromosome Organization
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Transcription, DNA-templated
Regulation Of Gene Expression
Regulation Of RNA Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of RNA Biosynthetic Process
Organelle Organization
Gene Expression
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
RNA Metabolic Process
Macromolecule Biosynthetic Process
Peptidyl-lysine Modification
Cellular Nitrogen Compound Metabolic Process
Regulation Of Metabolic Process
Cellular Protein Modification Process
Nitrogen Compound Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Peptidyl-amino Acid Modification
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of Gene Expression
Histone Methylation
Negative Regulation Of RNA Biosynthetic Process
Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
Protein Methylation
Cellular Metabolic Process
Methylation
Regulation Of Cellular Process
Cellular Protein Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Gene Expression, Epigenetic
Histone Lysine Methylation
Peptidyl-lysine Methylation
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Protein Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Gene Expression
Chromatin Organization
Chromosome Organization
Chromatin Modification
Histone Modification
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Gene Expression
Positive Regulation Of Transcription, DNA-templated
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Organelle Organization
Positive Regulation Of Cellular Biosynthetic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Gene Expression
Negative Regulation Of RNA Biosynthetic Process
Histone Acetylation
Internal Peptidyl-lysine Acetylation
Transcription, DNA-templated
Peptidyl-lysine Acetylation
Internal Protein Amino Acid Acetylation
RNA Biosynthetic Process
Protein Acetylation
Nucleosome Organization
Negative Regulation Of Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Cellular Metabolic Process
Regulation Of Metabolic Process
DNA Metabolic Process
DNA Replication-dependent Nucleosome Assembly
Positive Regulation Of Cellular Metabolic Process
Nucleosome Assembly
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
RNA Metabolic Process
Chromatin Assembly
Histone H4 Acetylation
Peptidyl-lysine Modification
DNA Methylation On Cytosine
Chromatin Assembly Or Disassembly
Positive Regulation Of Metabolic Process
Tagcloud
?
1st
affymetrix
barcoding
capn6
comprehensively
corneal
corneas
dystrophies
dystrophy
fecd
fecd4
fuchs
genechip
hcenc
hspa2
hybridized
itgbl1
nalcn
partek
polymorphous
ppcd
ppcd1
prex2
scientists
suite
tac1
tmod1
xecd
Tagcloud (Difference)
?
1st
affymetrix
barcoding
capn6
comprehensively
corneal
corneas
dystrophies
dystrophy
fecd
fecd4
fuchs
genechip
hcenc
hspa2
hybridized
itgbl1
nalcn
partek
polymorphous
ppcd
ppcd1
prex2
scientists
suite
tac1
tmod1
xecd
Tagcloud (Intersection)
?