HIST2H2BE and MAP4K4

  • Number of citations of the paper that reports this interaction (PMID 20936779)
  • 48
  • Data Source:
  • BioGRID (two hybrid)

HIST2H2BE

MAP4K4

Gene Name histone cluster 2, H2be mitogen-activated protein kinase kinase kinase kinase 4
Image No pdb structure No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
Protein-Protein Interactions 74 interactors: AIRE AKT1 ANP32A ARID1B ATF2 ATXN7L3 BAZ1B BRD2 BRD7 CDK9 CHFR CREBBP DNMT3L DYRK2 EP300 GADD45A GATAD2A GATAD2B GZMA HDAC2 HIPK2 HIRA HIRIP3 HIST1H4A HIST2H2AC HSPD1 IL33 IL7R KAT2A KAT2B KPNA1 LALBA LOX MAP4K4 MDM2 MSL1 MSL2 MST1 NAP1L4 NCL NPM1 PARP10 PBRM1 PELP1 PRMT6 PTMA RAG1 RCC1 RNF20 RNF40 RNF8 RPS6KA5 SAP30 SART3 SIRT7 SMARCA4 SSRP1 STK4 TAF1A TAF1B TBL1X TBL1XR1 TCF20 TGM2 TNPO1 TSPY1 UBC UBE2A USP12 USP15 USP22 USP46 USP49 VRK1 18 interactors: BRCA1 CASP8 DOK1 GBP3 HIST2H2BE ITGB1 KIF26B KIF5A MAP3K7 NCK1 NME7 PPP1CA PPP1CC PRKCE RAP2A RASA1 SLC9A1 TBPL2
Entrez ID 8349 9448
HPRD ID 03494 05235
Ensembl ID ENSG00000184678 ENSG00000071054
Uniprot IDs Q16778 B7Z3V5 O95819
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
5p15  angiogenesis  aza  bdkrb2  biomarker  dc  encoding  fgf7  gastric  global  heterozygosity  hypermethylation  immunoprecipitation  invasion  irx1  located  locus  lost  microarray  n87  nci  partially  restored  restoring  serve  sgc  susceptibility  transfection  tumorigenesis 
abstract  array  cascade  complicated  crc  downregulated  downstream  dual  evidences  explored  jun  kaplan  luciferase  mdm2  meier  microarray  micrornas  mir  mirna  mirnas  multistep  noncancerous  numerous  obstacles  obviously  reporter  serve  tnm  tumorigenesis 
Tagcloud (Difference) ?
5p15  angiogenesis  aza  bdkrb2  biomarker  dc  encoding  fgf7  gastric  global  heterozygosity  hypermethylation  immunoprecipitation  invasion  irx1  located  locus  lost  n87  nci  partially  restored  restoring  sgc  susceptibility  transfection 
abstract  array  cascade  complicated  crc  downregulated  downstream  dual  evidences  explored  jun  kaplan  luciferase  mdm2  meier  micrornas  mir  mirna  mirnas  multistep  noncancerous  numerous  obstacles  obviously  reporter  tnm 
Tagcloud (Intersection) ?
microarray  serve  tumorigenesis