USP11 and RANBP9

Number of citations of the paper that reports this interaction (PMID 12084015)
17

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		USP11	RANBP9
Gene Name		ubiquitin specific peptidase 11	RAN binding protein 9
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Cytosol Microtubule Associated Complex
	Molecular Function	Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity Protein Binding	Protein Binding Ran GTPase Binding Enzyme Binding
	Biological Process	Protein Deubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process	Protein Complex Assembly Microtubule Nucleation Axon Guidance
Pathways		Protein folding Chaperonin-mediated protein folding Association of TriC/CCT with target proteins during biosynthesis	Axon guidance L1CAM interactions
Drugs
Diseases
GWAS			Breast cancer ( 23535729)
Protein-Protein Interactions		10 interactors: BMI1 BRCA2 CBX8 PCGF2 RANBP9 RELB RNF2 SETDB1 TBL3 UBC	51 interactors: ADAP1 ADAP2 APC AR AXL BACE1 BRCA1 CACNA1G CALB1 CBS CDK11B CLEC7A DDX4 DISC1 DYRK1B ENTPD1 ESR1 FMR1 HIPK2 HMBS HNF4G ITGAL ITGB2 L1CAM MAPK6 MET MKLN1 MPHOSPH8 NCOA6 NCOR2 OPRM1 PPARD PPARG PPP1CA PRKACA RAF1 RAN S100A7 SMAD2 SMAD3 SMAD9 SOS1 SPP1 TFRC THRA THRB TP53 TP73 UCHL1 USP11 WNK1
Entrez ID		8237	10048
HPRD ID		02081	04835
Ensembl ID		ENSG00000102226	ENSG00000010017
Uniprot IDs		B4DGK3 P51784	Q96S59
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone Modification Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Chromatin Modification Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Chromatin Organization Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Histone Ubiquitination Chromosome Organization Regulation Of Transcription From RNA Polymerase II Promoter Protein Ubiquitination Peptidyl-lysine Modification Protein Modification By Small Protein Conjugation Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Nitrogen Compound Metabolic Process Protein Acetylation Inner Cell Mass Cell Proliferation Regulation Of Transcription, DNA-templated In Utero Embryonic Development Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Embryo Development Blastocyst Growth Organelle Organization Cellular Protein Modification Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Gene Expression Anterior/posterior Pattern Specification Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Ubiquitin-protein Transferase Activity	Multicellular Organismal Development Anatomical Structure Development Developmental Process System Development Organ Development Response To Organic Substance Transcription Initiation From RNA Polymerase II Promoter Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Cell Communication Cellular Response To Organic Substance Signal Transduction Cellular Response To Organic Cyclic Compound Signaling DNA-templated Transcription, Initiation Cellular Response To Stimulus Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Intracellular Receptor Signaling Pathway Regulation Of Signaling Positive Regulation Of Metabolic Process Anatomical Structure Morphogenesis Response To Stimulus Response To Organic Cyclic Compound Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Tissue Development Response To Lipid Nervous System Development Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Cellular Process Steroid Hormone Mediated Signaling Pathway Response To Growth Factor Epithelium Development Wound Healing Negative Regulation Of Signal Transduction Regulation Of Cell Proliferation Response To Hormone Reproductive Process Regulation Of Intracellular Signal Transduction Apoptotic Process Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Cell Death Positive Regulation Of Intracellular Signal Transduction Hormone-mediated Signaling Pathway Cell Activation Negative Regulation Of Signaling DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator
Tagcloud ?		arrest attenuated broad complexes controlled coordinates damage deubiquitinating double dramatically forms immunoprecipitation leading mdm2 minute murine p53 primarily protease regulator repair reveal stability stabilizes stresses suppressor tightly ubiquitin understand	accelerates apdeltae9 brains cortex cortical deficits dendritic density egfp exacerbated hippocampus immunoreactive learning mushroom plaque puncta reductions skills spine spines spinophilin striking synapses thin traces transgenic triple vulnerable wt
Tagcloud (Difference) ?		arrest attenuated broad complexes controlled coordinates damage deubiquitinating double dramatically forms immunoprecipitation leading mdm2 minute murine p53 primarily protease regulator repair reveal stability stabilizes stresses suppressor tightly ubiquitin understand	accelerates apdeltae9 brains cortex cortical deficits dendritic density egfp exacerbated hippocampus immunoreactive learning mushroom plaque puncta reductions skills spine spines spinophilin striking synapses thin traces transgenic triple vulnerable wt
Tagcloud (Intersection) ?