USP11 and RELB

Number of citations of the paper that reports this interaction (PMID 14743216)
197

Data Source:
HPRD (in vitro)

		USP11	RELB
Gene Name		ubiquitin specific peptidase 11	v-rel avian reticuloendotheliosis viral oncogene homolog B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleoplasm Cytoplasm Microtubule Organizing Center Cytosol I-kappaB/NF-kappaB Complex
	Molecular Function	Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Core Promoter Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding
	Biological Process	Protein Deubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Inflammatory Response I-kappaB Kinase/NF-kappaB Signaling Antigen Processing And Presentation Circadian Regulation Of Gene Expression Response To Cytokine NIK/NF-kappaB Signaling Myeloid Dendritic Cell Differentiation T-helper 1 Cell Differentiation Innate Immune Response Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Osmotic Stress
Pathways		Protein folding Chaperonin-mediated protein folding Association of TriC/CCT with target proteins during biosynthesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: BMI1 BRCA2 CBX8 PCGF2 RANBP9 RELB RNF2 SETDB1 TBL3 UBC	25 interactors: BCL7A BUD31 CDK1 CTSL DPF2 EHMT2 EZH2 GSK3B HDAC6 KPNA2 KPNA6 MALT1 MT1M MTAP NFKB1 NFKB2 RELA SIN3A SMARCA4 SMARCB1 SMARCC1 SMARCC2 SMARCE1 UQCRFS1 USP11
Entrez ID		8237	5971
HPRD ID		02081	06886
Ensembl ID		ENSG00000102226	ENSG00000104856
Uniprot IDs		B4DGK3 P51784	D6R992 Q01201
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone Modification Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Chromatin Modification Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Chromatin Organization Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Histone Ubiquitination Chromosome Organization Regulation Of Transcription From RNA Polymerase II Promoter Protein Ubiquitination Peptidyl-lysine Modification Protein Modification By Small Protein Conjugation Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Nitrogen Compound Metabolic Process Protein Acetylation Inner Cell Mass Cell Proliferation Regulation Of Transcription, DNA-templated In Utero Embryonic Development Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Embryo Development Blastocyst Growth Organelle Organization Cellular Protein Modification Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Gene Expression Anterior/posterior Pattern Specification Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Ubiquitin-protein Transferase Activity	Nucleosome Disassembly Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Modification Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Chromatin Organization Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated ATP-dependent Chromatin Remodeling Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Activation Of Innate Immune Response Positive Regulation Of Macromolecule Biosynthetic Process Response To Organic Substance Negative Regulation Of Gene Expression Chromosome Organization Positive Regulation Of Innate Immune Response Positive Regulation Of Cellular Metabolic Process Protein Complex Disassembly Regulation Of Gene Expression, Epigenetic Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity NIK/NF-kappaB Signaling Regulation Of Metabolic Process Toll-like Receptor Signaling Pathway Nucleobase-containing Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Innate Immune Response Positive Regulation Of Cellular Biosynthetic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Negative Regulation Of Cellular Metabolic Process Immune Response-regulating Signaling Pathway Nucleosome Organization Response To Inorganic Substance Positive Regulation Of Transcription, DNA-templated Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Cellular Response To Hydrogen Peroxide Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Chromatin Assembly Or Disassembly Positive Regulation Of Transcription From RNA Polymerase II Promoter
Tagcloud ?		arrest attenuated broad complexes controlled coordinates damage deubiquitinating double dramatically forms immunoprecipitation leading mdm2 minute murine p53 primarily protease regulator repair reveal stability stabilizes stresses suppressor tightly ubiquitin understand	balpha bbeta bepsilon biochemically casein ck complexed conjugation correspond crel ikappa ikappab ikk1 ikks indirectly initiates locate nonstimulated okadaic p100 p105 p90rsk1 pest phosphorylating purify rela s32 s36 serines
Tagcloud (Difference) ?		arrest attenuated broad complexes controlled coordinates damage deubiquitinating double dramatically forms immunoprecipitation leading mdm2 minute murine p53 primarily protease regulator repair reveal stability stabilizes stresses suppressor tightly ubiquitin understand	balpha bbeta bepsilon biochemically casein ck complexed conjugation correspond crel ikappa ikappab ikk1 ikks indirectly initiates locate nonstimulated okadaic p100 p105 p90rsk1 pest phosphorylating purify rela s32 s36 serines
Tagcloud (Intersection) ?