SFXN3 and TLCD4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SFXN3	TLCD4
Description		sideroflexin 3	TLC domain containing 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Mitochondrial Membrane	Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Monoatomic Ion Transmembrane Transporter Activity L-serine Transmembrane Transporter Activity Transmembrane Transporter Activity	Protein Binding
	Biological Process	One-carbon Metabolic Process Monoatomic Ion Transport Amino Acid Transport L-serine Transport Monoatomic Ion Transmembrane Transport Transmembrane Transport Serine Import Into Mitochondrion Mitochondrial Transmembrane Transport	Lipid Homeostasis
Pathways
Drugs
Diseases
GWAS		Refractive error ( 32231278) Regular attendance at a pub or social club ( 29970889)
Interacting Genes		14 interacting genes: AQP6 CREB3 FCER1G HSD17B11 HSD17B13 LEPROTL1 REEP4 RETREG3 RUSF1 SCN3B TLCD4 TMEM14B TMEM51 TMX2	72 interacting genes: ADGRB3 ADGRE2 ARV1 ATP13A1 BNIP3 CACNG1 CCDC167 CDIPT CFTR CHPT1 CLCN7 CLEC7A CMTM5 COMT CTXN3 CXCL16 CYP4F2 CYP4F22 DHRSX EBP EMC6 EMP1 ERG28 FA2H FDFT1 FXYD6 FXYD6-FXYD2 GJB2 GOSR2 GYPA HMOX1 IGFBP5 KRT1 LNPEP MS4A13 MYG1 NAT8 NDUFA3 NINJ1 NKG7 ORMDL1 PMP22 PRAF2 PRRT2 REEP6 SCAMP5 SCD SEC22A SEC22B SERP1 SFXN1 SFXN3 SLC41A1 SLC67A1 SMAGP STATH STX12 SYNDIG1 SYNJ2BP TIMM23 TMEM115 TMEM120B TMEM19 TMEM229B TMEM237 TMEM60 TMIE TVP23B UBE2J1 VEZT YIPF1 YIPF4
Entrez ID		81855	148534
HPRD ID		15329	08110
Ensembl ID		ENSG00000107819	ENSG00000152078
Uniprot IDs		B4DRS6 Q9BWM7	Q96MV1
PDB IDs
Enriched GO Terms of Interacting Partners?		Steroid Dehydrogenase Activity Endoplasmic Reticulum Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Nitrate Transmembrane Transporter Activity Membrane IgE Receptor Activity Positive Regulation Of Deacetylase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Sterol Biosynthetic Process Lipid Biosynthetic Process Cholesterol Biosynthetic Process SNAP Receptor Activity Steroid Biosynthetic Process Membrane Fusion Serine Import Into Mitochondrion Lipid Metabolic Process Sterol Metabolic Process Cholesterol Transport Establishment Of Protein Localization Sterol Transport Membrane Organization Organic Cation Transport Import Into The Mitochondrion Protein Transport L-serine Transmembrane Transporter Activity L-serine Transport Protein Binding Bleb Assembly Serine Transport Vesicle Fusion
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