SFXN3 and TMEM51

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SFXN3	TMEM51
Description		sideroflexin 3	transmembrane protein 51
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Mitochondrial Membrane	Membrane
	Molecular Function	Protein Binding Monoatomic Ion Transmembrane Transporter Activity L-serine Transmembrane Transporter Activity Transmembrane Transporter Activity	Protein Binding
	Biological Process	One-carbon Metabolic Process Monoatomic Ion Transport Amino Acid Transport L-serine Transport Monoatomic Ion Transmembrane Transport Transmembrane Transport Serine Import Into Mitochondrion Mitochondrial Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Refractive error ( 32231278) Regular attendance at a pub or social club ( 29970889)	Acute ischemic stroke x type 2 diabetes interaction ( 32541925) Cocaine use disorder ( 31490055) Cocaine use disorder x non-traditional parental care interaction ( 31490055)
Interacting Genes		14 interacting genes: AQP6 CREB3 FCER1G HSD17B11 HSD17B13 LEPROTL1 REEP4 RETREG3 RUSF1 SCN3B TLCD4 TMEM14B TMEM51 TMX2	38 interacting genes: AQP6 ARLN BCL2L13 C14orf180 CCDC167 CCL4L2 CLCA4 CREB3 CYB5R3 CYP4F2 EBP GET3 ITCH LMNA MRPL12 NEDD4 NINJ2 PLP2 PTPN5 REEP4 RTP2 SEC61G SFT2D2 SFXN3 SMAGP SMIM1 STRIT1 TMEM107 TMEM14A TMEM14B TMEM242 TMEM254 TMIE TMX2 TSNARE1 UBE2J1 VAMP4 VTI1B
Entrez ID		81855	55092
HPRD ID		15329	07651
Ensembl ID		ENSG00000107819	ENSG00000171729
Uniprot IDs		B4DRS6 Q9BWM7	Q9BSA0 Q9NW97
PDB IDs
Enriched GO Terms of Interacting Partners?		Steroid Dehydrogenase Activity Endoplasmic Reticulum Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Nitrate Transmembrane Transporter Activity Membrane IgE Receptor Activity Positive Regulation Of Deacetylase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor	Membrane Endoplasmic Reticulum Membrane Mitochondrial Membrane Presynaptic Endosome Membrane Endoplasmic Reticulum SNARE Complex
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