ZFC3H1 and NINL

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ZFC3H1	NINL
Description		zinc finger C3H1-type containing	ninein like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Nucleolus MTREC Complex	Cytoplasm Centrosome Cytosol Cytoskeleton Microtubule
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Calcium Ion Binding Protein Binding Metal Ion Binding
	Biological Process	RNA Processing	Microtubule Anchoring At Centrosome
Pathways		Nuclear RNA decay	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)	Brain morphology (MOSTest) ( 32665545) Macular thickness ( 30535121) Telomere length ( 30185882) Urate levels ( 31578528)
Interacting Genes		23 interacting genes: APP CADPS CCDC57 CCDC85B CEP70 COG6 CSNK2A1 DOCK8 GOLGA2 GRIK1 HNRNPK HSF2BP ITSN1 KHDRBS2 MKRN3 MTUS2 NINL PIBF1 RNF10 SPAG5 SRPK2 TRIM27 ZDHHC17	52 interacting genes: AKAP17A APEX2 AURKB CBY2 CCDC146 CCDC33 CCHCR1 CLEC1B DCTN5 ELOA ERBB2 EWSR1 EZH2 FAM107A FAM161A GCC1 GPKOW HAUS1 JUNB KANSL1 KAT5 KAT7 KRT1 L3MBTL4 LRSAM1 LZTS2 MAD1L1 MBIP MCM10 PLK1 PRPF18 PRPF3 RBM41 RCOR3 RGS2 RIBC2 RNF40 SH2D4A SH3BP5L SYT17 TCEANC TNNT1 TSC1 TSPYL4 UTP14A YJU2B ZFC3H1 ZFHX3 ZNF250 ZNF417 ZNF426 ZNF646
Entrez ID		196441	22981
HPRD ID		14489	11120
Ensembl ID		ENSG00000133858	ENSG00000101004
Uniprot IDs		O60293	Q9Y2I6
PDB IDs
Enriched GO Terms of Interacting Partners?		Centrosome	Mitotic Spindle Pole Nucleus Protein Binding Chromosome, Centromeric Region Positive Regulation Of Mitotic Sister Chromatid Segregation Spindle Pole Regulation Of Metaphase Plate Congression Kinetochore Attachment Of Mitotic Spindle Microtubules To Kinetochore Histone Acetyltransferase Complex Positive Regulation Of Chromosome Segregation Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Histone H4K16 Acetyltransferase Activity Spindle Microtubule Protein Localization To Chromosome Regulation Of Sister Chromatid Segregation Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of RNA Metabolic Process Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Cytoskeleton Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Positive Regulation Of Attachment Of Spindle Microtubules To Kinetochore Spindle Midzone Assembly Histone H4 Acetyltransferase Activity Peptidyl-lysine Acetylation Negative Regulation Of Cell Cycle Phase Transition Zinc Ion Binding Regulation Of Chromosome Segregation Regulation Of Mitotic Sister Chromatid Separation RNA Splicing Centrosome
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