SLC38A1 and PGRMC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC38A1	PGRMC2
Description		solute carrier family 38 member 1	progesterone receptor membrane component 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Basolateral Plasma Membrane Axon Neuronal Cell Body Extracellular Exosome External Side Of Apical Plasma Membrane	Extracellular Region Nucleus Nuclear Envelope Nucleoplasm Endoplasmic Reticulum Endomembrane System Membrane Synapse Glutamatergic Synapse
	Molecular Function	Amino Acid:sodium Symporter Activity Neutral L-amino Acid:sodium Symporter Activity Proline:sodium Symporter Activity Protein Binding Amino Acid Transmembrane Transporter Activity Neutral L-amino Acid Transmembrane Transporter Activity L-amino Acid Transmembrane Transporter Activity L-glutamine Transmembrane Transporter Activity Symporter Activity Glycine:sodium Symporter Activity Alanine:sodium Symporter Activity	Nuclear Steroid Receptor Activity Steroid Binding Protein Binding Lipid Binding Heme Transmembrane Transporter Activity Heme Binding
	Biological Process	Neurotransmitter Uptake Amino Acid Transmembrane Transport Monoatomic Ion Transport Sodium Ion Transport Amino Acid Transport Glutamine Transport Female Pregnancy Gamma-aminobutyric Acid Biosynthetic Process Neutral Amino Acid Transport Glycine Transport Regulation Of Synaptic Transmission, GABAergic Alanine Transport Sodium Ion Transmembrane Transport Amino Acid Import Regulation Of Synaptic Plasticity Transport Across Blood-brain Barrier L-alpha-amino Acid Transmembrane Transport L-glutamine Import Across Plasma Membrane	Heme Transport Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Adipose Tissue Development
Pathways		Astrocytic Glutamate-Glutamine Uptake And Metabolism Amino acid transport across the plasma membrane	RHOA GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle Heme signaling
Drugs		Asparagine
Diseases
GWAS		Appendicular lean mass ( 33097823) Birth weight ( 31043758) Gout ( 32238385) Morning person ( 30696823) Offspring birth weight ( 31043758) Refractive error ( 32231278)	Bone mineral density (total hip) ( 29883787)
Interacting Genes		30 interacting genes: AMIGO1 AQP6 BMP10 C1QL4 CD79A CREB3 FATE1 FFAR2 GPR152 GPR42 GRM2 IGFBP5 IL1RL1 PDCD1LG2 PGRMC2 PMP22 PTPN11 RPRM SCGB1D1 SCN3B SERP2 SLC10A1 SLC10A6 SLC13A4 SMIM3 SSMEM1 STRIT1 TMEM60 TMPPE TRARG1	55 interacting genes: AQP10 ART5 BAG4 C5 COX20 CYB561D2 CYP4F2 DGAT2L6 DHRSX EI24 FA2H FAXDC2 FXYD6 FXYD6-FXYD2 GET3 GHITM GPR151 ITGAM ITPRIP LINC00632 LPAR3 MALL MFHAS1 ORMDL1 PEDS1-UBE2V1 PEX16 PLLP PMP22 RNF8 RUSF1 SFXN1 SLC16A13 SLC30A8 SLC38A1 SLC39A13 SLC9B2 SMPD2 ST6GAL2 STX3 TAS2R19 TECR TF TMEM107 TMEM187 TMEM19 TMEM208 TMEM60 TMEM86A TMEM86B TSPAN2 UBXN8 VEZT YIPF2 ZDHHC21 ZFPL1
Entrez ID		81539	10424
HPRD ID		12245	09665
Ensembl ID		ENSG00000111371	ENSG00000164040
Uniprot IDs		F8VX04 Q9H2H9	O15173
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Bile Acid:sodium Symporter Activity	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Myelination Axon Ensheathment Alkenylglycerophosphocholine Hydrolase Activity Compact Myelin
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