SLC38A1 and SCGB1D1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC38A1	SCGB1D1
Description		solute carrier family 38 member 1	secretoglobin family 1D member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Basolateral Plasma Membrane Axon Neuronal Cell Body Extracellular Exosome External Side Of Apical Plasma Membrane	Extracellular Region Extracellular Space
	Molecular Function	Amino Acid:sodium Symporter Activity Neutral L-amino Acid:sodium Symporter Activity Proline:sodium Symporter Activity Protein Binding Amino Acid Transmembrane Transporter Activity Neutral L-amino Acid Transmembrane Transporter Activity L-amino Acid Transmembrane Transporter Activity L-glutamine Transmembrane Transporter Activity Symporter Activity Glycine:sodium Symporter Activity Alanine:sodium Symporter Activity	Protein Binding
	Biological Process	Neurotransmitter Uptake Amino Acid Transmembrane Transport Monoatomic Ion Transport Sodium Ion Transport Amino Acid Transport Glutamine Transport Female Pregnancy Gamma-aminobutyric Acid Biosynthetic Process Neutral Amino Acid Transport Glycine Transport Regulation Of Synaptic Transmission, GABAergic Alanine Transport Sodium Ion Transmembrane Transport Amino Acid Import Regulation Of Synaptic Plasticity Transport Across Blood-brain Barrier L-alpha-amino Acid Transmembrane Transport L-glutamine Import Across Plasma Membrane
Pathways		Astrocytic Glutamate-Glutamine Uptake And Metabolism Amino acid transport across the plasma membrane
Drugs		Asparagine
Diseases
GWAS		Appendicular lean mass ( 33097823) Birth weight ( 31043758) Gout ( 32238385) Morning person ( 30696823) Offspring birth weight ( 31043758) Refractive error ( 32231278)	Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		30 interacting genes: AMIGO1 AQP6 BMP10 C1QL4 CD79A CREB3 FATE1 FFAR2 GPR152 GPR42 GRM2 IGFBP5 IL1RL1 PDCD1LG2 PGRMC2 PMP22 PTPN11 RPRM SCGB1D1 SCN3B SERP2 SLC10A1 SLC10A6 SLC13A4 SMIM3 SSMEM1 STRIT1 TMEM60 TMPPE TRARG1	7 interacting genes: CHODL CREB3L1 FAM209A FFAR2 OPRM1 SCGB2A1 SLC38A1
Entrez ID		81539	10648
HPRD ID		12245	18025
Ensembl ID		ENSG00000111371	ENSG00000168515
Uniprot IDs		F8VX04 Q9H2H9	O95968
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Bile Acid:sodium Symporter Activity	Positive Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Protein Transport Negative Regulation Of Protein Secretion Cellular Response To Morphine Morphine Receptor Activity Negative Regulation Of Wnt Protein Secretion Beta-endorphin Receptor Activity Alanine:sodium Symporter Activity Amino Acid Import Glycine:sodium Symporter Activity Extracellular Matrix Constituent Secretion Negative Regulation Of Establishment Of Protein Localization Negative Regulation Of Secretion Negative Regulation Of Secretion By Cell Regulation Of NMDA Receptor Activity Proline:sodium Symporter Activity Neutral L-amino Acid:sodium Symporter Activity L-glutamine Import Across Plasma Membrane Leukocyte Chemotaxis Involved In Inflammatory Response Negative Regulation Of Protein Localization Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway G Protein-coupled Opioid Receptor Activity L-glutamine Transmembrane Transporter Activity External Side Of Apical Plasma Membrane Amino Acid:sodium Symporter Activity Glutamine Transport Gamma-aminobutyric Acid Biosynthetic Process Gamma-aminobutyric Acid Metabolic Process Positive Regulation Of Neurogenesis G Protein-coupled Opioid Receptor Signaling Pathway
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