PGRMC2 and TMEM19

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PGRMC2	TMEM19
Description		progesterone receptor membrane component 2	transmembrane protein 19
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Nuclear Envelope Nucleoplasm Endoplasmic Reticulum Endomembrane System Membrane Synapse Glutamatergic Synapse	Membrane
	Molecular Function	Nuclear Steroid Receptor Activity Steroid Binding Protein Binding Lipid Binding Heme Transmembrane Transporter Activity Heme Binding	Protein Binding
	Biological Process	Heme Transport Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Adipose Tissue Development
Pathways		RHOA GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle Heme signaling
Drugs
Diseases
GWAS		Bone mineral density (total hip) ( 29883787)	Nonsyndromic cleft lip with cleft palate ( 28232668)
Interacting Genes		55 interacting genes: AQP10 ART5 BAG4 C5 COX20 CYB561D2 CYP4F2 DGAT2L6 DHRSX EI24 FA2H FAXDC2 FXYD6 FXYD6-FXYD2 GET3 GHITM GPR151 ITGAM ITPRIP LINC00632 LPAR3 MALL MFHAS1 ORMDL1 PEDS1-UBE2V1 PEX16 PLLP PMP22 RNF8 RUSF1 SFXN1 SLC16A13 SLC30A8 SLC38A1 SLC39A13 SLC9B2 SMPD2 ST6GAL2 STX3 TAS2R19 TECR TF TMEM107 TMEM187 TMEM19 TMEM208 TMEM60 TMEM86A TMEM86B TSPAN2 UBXN8 VEZT YIPF2 ZDHHC21 ZFPL1	38 interacting genes: APOA5 AQP6 BSCL2 C10orf67 CD3G CD79A CNR2 CPLX4 CREB3 CREB3L1 ELOVL4 FAM210B FCER1G GJB1 GORAB GPR42 GPRC5D GPX8 HSD17B13 KASH5 LDAF1 LEPROTL1 LY6E MC4R PGRMC2 PIGP PTGES REEP4 RNF185 SERTM1 SLC71A2 SLC7A1 SUSD6 TEX29 TLCD4 TMEM139 TMEM14B TMEM45A
Entrez ID		10424	55266
HPRD ID		09665	15530
Ensembl ID		ENSG00000164040	ENSG00000139291
Uniprot IDs		O15173	Q96HH6
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Myelination Axon Ensheathment Alkenylglycerophosphocholine Hydrolase Activity Compact Myelin	Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Protein Binding
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