SLC38A1 and TMPPE

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC38A1	TMPPE
Description		solute carrier family 38 member 1	transmembrane protein with metallophosphoesterase domain
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Basolateral Plasma Membrane Axon Neuronal Cell Body Extracellular Exosome External Side Of Apical Plasma Membrane	Membrane
	Molecular Function	Amino Acid:sodium Symporter Activity Neutral L-amino Acid:sodium Symporter Activity Proline:sodium Symporter Activity Protein Binding Amino Acid Transmembrane Transporter Activity Neutral L-amino Acid Transmembrane Transporter Activity L-amino Acid Transmembrane Transporter Activity L-glutamine Transmembrane Transporter Activity Symporter Activity Glycine:sodium Symporter Activity Alanine:sodium Symporter Activity	Protein Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Neurotransmitter Uptake Amino Acid Transmembrane Transport Monoatomic Ion Transport Sodium Ion Transport Amino Acid Transport Glutamine Transport Female Pregnancy Gamma-aminobutyric Acid Biosynthetic Process Neutral Amino Acid Transport Glycine Transport Regulation Of Synaptic Transmission, GABAergic Alanine Transport Sodium Ion Transmembrane Transport Amino Acid Import Regulation Of Synaptic Plasticity Transport Across Blood-brain Barrier L-alpha-amino Acid Transmembrane Transport L-glutamine Import Across Plasma Membrane
Pathways		Astrocytic Glutamate-Glutamine Uptake And Metabolism Amino acid transport across the plasma membrane
Drugs		Asparagine
Diseases
GWAS		Appendicular lean mass ( 33097823) Birth weight ( 31043758) Gout ( 32238385) Morning person ( 30696823) Offspring birth weight ( 31043758) Refractive error ( 32231278)	Asthma ( 31619474 31959851) Asthma (childhood onset) ( 31036433)
Interacting Genes		30 interacting genes: AMIGO1 AQP6 BMP10 C1QL4 CD79A CREB3 FATE1 FFAR2 GPR152 GPR42 GRM2 IGFBP5 IL1RL1 PDCD1LG2 PGRMC2 PMP22 PTPN11 RPRM SCGB1D1 SCN3B SERP2 SLC10A1 SLC10A6 SLC13A4 SMIM3 SSMEM1 STRIT1 TMEM60 TMPPE TRARG1	35 interacting genes: AGTRAP ASGR2 CD79A CLDND2 CLRN1 CNR2 CYB561 FIS1 FXYD6 FXYD6-FXYD2 GPR152 IER3IP1 KCNJ6 KLRC1 LEMD1 MS4A1 PLLP PLPPR1 PNLIPRP1 REEP6 RETREG3 RTP2 SCN3B SFXN5 SLAMF6 SLC38A1 SMAGP SSMEM1 STX3 STX8 TMEM60 TMIE TRARG1 VAMP3 YIPF1
Entrez ID		81539	643853
HPRD ID		12245	18951
Ensembl ID		ENSG00000111371	ENSG00000188167
Uniprot IDs		F8VX04 Q9H2H9	Q6ZT21
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Bile Acid:sodium Symporter Activity	Membrane Plasma Membrane Organelle Membrane Fusion SNAP Receptor Activity Vesicle Fusion SNARE Complex Organelle Fusion Membrane Fusion Vesicle Docking Endoplasmic Reticulum Organization Organelle Localization By Membrane Tethering External Side Of Plasma Membrane Membrane Docking
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