ZSCAN16 and ZNF446

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)
HPRD (two hybrid)

		ZSCAN16	ZNF446
Description		zinc finger and SCAN domain containing 16	zinc finger protein 446
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Extracellular Space Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)	Obesity-related traits ( 23251661) Uric acid clearance ( 28095793)
Interacting Genes		13 interacting genes: AP1M1 APP NTAQ1 PPL SCAND1 SLC25A38 TRIM41 TRIM55 TRIM63 ZNF24 ZNF446 ZSCAN22 ZSCAN32	54 interacting genes: ACTN2 ANKRD1 CCNK COPS2 CYSRT1 DGCR6 DGCR6L EHMT2 EVI5 FHL5 FRMD8 FRS3 GOLGA6L9 INCA1 KIFC3 KRT31 KRT34 KRT35 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP3-1 LNX1 LZTS2 MAGOHB MDFI NBPF19 NOTCH2NLA PIN1 REL SCAND1 SIVA1 SUFU TAX1BP1 TRIM27 UBE2I UBE3A ZKSCAN7 ZNF165 ZNF18 ZNF232 ZNF24 ZNF263 ZNF496 ZSCAN12 ZSCAN16 ZSCAN18 ZSCAN21 ZSCAN22 ZSCAN29 ZSCAN30 ZSCAN32 ZSCAN9
Entrez ID		80345	55663
HPRD ID		15792	07934
Ensembl ID		ENSG00000196812	ENSG00000083838
Uniprot IDs		B4DFB7 Q9H4T2	Q9NWS9
PDB IDs		2COT
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Response To Interleukin-1 Innate Immune Response Regulation Of ATP Metabolic Process Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Defense Response To Symbiont Regulation Of Response To Calcium Ion Regulation Of Carbohydrate Catabolic Process Regulation Of Glycolytic Process Defense Response To Other Organism Amylin Binding Metal Ion Binding Regulation Of Purine Nucleotide Metabolic Process Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Identical Protein Binding Zinc Ion Binding Glycine Import Into Mitochondrion Protein-N-terminal Asparagine Amidohydrolase Activity Protein-N-terminal Glutamine Amidohydrolase Activity Ubiquitin Protein Ligase Activity Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation	Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Keratin Filament Regulation Of RNA Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Zinc Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Intermediate Filament Regulation Of Gene Expression Structural Constituent Of Skin Epidermis Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process DNA Binding Nucleus Regulation Of Metabolic Process Intermediate Filament Organization Metal Ion Binding Postsynaptic Cytosol Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Molecule Activity Protein Binding Sequence-specific Double-stranded DNA Binding Titin Binding
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