TRAF3IP3 and NDEL1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TRAF3IP3	NDEL1
Gene Name		TRAF3 interacting protein 3	nudE neurodevelopment protein 1-like 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane	Kinetochore Condensed Chromosome Kinetochore Nuclear Envelope Nucleolus Cytoplasm Centrosome Spindle Cytosol Kinesin Complex Microtubule Cell Leading Edge Axon Hillock Neurofilament Cytoskeleton
	Molecular Function	Protein Binding	Protein Binding Microtubule Binding Alpha-tubulin Binding Beta-tubulin Binding Oligopeptidase Activity
	Biological Process		Establishment Of Mitotic Spindle Orientation Mitotic Cell Cycle Neuron Migration Inner Cell Mass Cell Proliferation Proteolysis Microtubule Nucleation Chromosome Segregation Mitotic Centrosome Separation Retrograde Axon Cargo Transport Regulation Of Neuron Projection Development Cell Migration Cerebral Cortex Radially Oriented Cell Migration Central Nervous System Neuron Axonogenesis Activation Of Cdc42 GTPase Activity Positive Regulation Of Axon Extension Vesicle Transport Along Microtubule Positive Regulation Of Axon Regeneration Nuclear Envelope Disassembly Establishment Of Chromosome Localization Centrosome Localization Neurofilament Cytoskeleton Organization Neuron Projection Extension
Pathways			Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: CCDC155 CDCA7L EMD FATE1 NDEL1 PSTPIP1 SP100 SSSCA1 TFIP11 TRAF3 TRIM36 WAC	58 interactors: AIMP2 ANK2 APP BMI1 CCDC88A CCHCR1 CCSER1 CCSER2 CDK5 CENPF CEP170 CEP63 CWF19L2 DISC1 DIXDC1 DTNB DYNC1H1 GOLGA2 IMMT KALRN KIFC3 KRT40 LUC7L2 MAGEA11 MBIP MIS18A MLLT10 MRC2 MTUS2 NDC80 NDE1 PAFAH1B1 PKP2 SNAPC5 SNX6 SYNE1 TACC3 TRAF3IP3 TRIM27 USP2 XPA YWHAE YWHAG ZNF10 ZNF17 ZNF180 ZNF197 ZNF211 ZNF230 ZNF260 ZNF264 ZNF417 ZNF490 ZNF544 ZNF572 ZNF599 ZNF844 ZNF91
Entrez ID		80342	81565
HPRD ID		16305	06340
Ensembl ID		ENSG00000009790	ENSG00000166579
Uniprot IDs		Q9Y228	Q9GZM8
PDB IDs			2V66
Enriched GO Terms of Interacting Partners?		Cell Cycle Process Regulation Of Protein Export From Nucleus Nuclear Envelope Disassembly Establishment Of Chromosome Localization Cell Cycle Nuclear Envelope Organization Chromosome Localization To Nuclear Envelope Involved In Synapsis Spliceosomal Complex Disassembly Histone H2B Conserved C-terminal Lysine Ubiquitination Negative Regulation Of Intracellular Protein Transport Regulation Of Fas Signaling Pathway Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Intracellular Transport Nucleus Organization Organelle Organization Protein Ubiquitination Protein Modification By Small Protein Conjugation Positive Regulation Of Axon Regeneration Negative Regulation Of Protein Export From Nucleus Retrograde Axon Cargo Transport Negative Regulation Of Protein Transport Mitotic Cell Cycle Process Intracellular Receptor Signaling Pathway Positive Regulation Of Neuron Projection Regeneration Activation Of Cdc42 GTPase Activity Histone H2B Ubiquitination Mitotic Cell Cycle Regulation Of Nucleocytoplasmic Transport Mitotic Nuclear Envelope Reassembly Mitotic Centrosome Separation Chromosome Segregation Neurofilament Cytoskeleton Organization Innate Immune Response Centrosome Separation Toll Signaling Pathway Negative Regulation Of Catenin Import Into Nucleus Nuclear Envelope Reassembly Cellular Response To DNA Damage Stimulus DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Regulation Of Intracellular Protein Transport DNA Damage Response, Signal Transduction Resulting In Transcription Regulation Of Axon Regeneration Positive Regulation Of Protein Export From Nucleus Positive Regulation Of Macroautophagy Positive Regulation Of Cdc42 GTPase Activity	G2/M Transition Of Mitotic Cell Cycle Regulation Of Metabolic Process Cerebral Cortex Development Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Cell Division Pallium Development Cell Cycle Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Biosynthetic Process Telencephalon Development Organelle Organization Cytoskeleton Organization Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Mitotic Cell Cycle Neural Precursor Cell Proliferation Microtubule-based Process Microtubule Cytoskeleton Organization Forebrain Development Regulation Of Gene Expression Cellular Process Cerebral Cortex Radially Oriented Cell Migration Mitotic Cell Cycle Process Nitrogen Compound Metabolic Process Regulation Of Heart Rate By Cardiac Conduction Organelle Localization Brain Development Neuron Migration Head Development Cerebral Cortex Cell Migration Movement Of Cell Or Subcellular Component Cell Cycle Process Mitotic Nuclear Division Establishment Of Organelle Localization Telencephalon Cell Migration Cardiac Muscle Cell Action Potential Forebrain Cell Migration Cellular Localization
Tagcloud ?		amplified approximate blotting construct constructed digested digestion egfp eukaryotic flag fluorescence foundation frame green hek293 inserted kd mononuclear pires2 plasmid precipitation reading restriction sali successfully tag teracting transfected xhoi	ammonis c57bl ca3 capillary cornu dentate dg disc1 disrupted epilepsy epilepticus erk etiology gyrus hippocampus homolog hypothesize lis1 lissencephaly meanwhile microtubule mitosis organization pilocarpine schizophrenia se seizure spontaneous vessels
Tagcloud (Difference) ?		amplified approximate blotting construct constructed digested digestion egfp eukaryotic flag fluorescence foundation frame green hek293 inserted kd mononuclear pires2 plasmid precipitation reading restriction sali successfully tag teracting transfected xhoi	ammonis c57bl ca3 capillary cornu dentate dg disc1 disrupted epilepsy epilepticus erk etiology gyrus hippocampus homolog hypothesize lis1 lissencephaly meanwhile microtubule mitosis organization pilocarpine schizophrenia se seizure spontaneous vessels
Tagcloud (Intersection) ?