WDCP and MED31

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		WDCP	MED31
Description		WD repeat and coiled coil containing	mediator complex subunit 31
Image		No pdb structure
GO Annotations	Cellular Component		Ubiquitin Ligase Complex Nucleus Nucleoplasm Mediator Complex Core Mediator Complex
	Molecular Function	Protein Binding Kinase Binding	Transcription Coregulator Activity Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Complex Oligomerization	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Protein Ubiquitination Positive Regulation Of Transcription Elongation By RNA Polymerase II Negative Regulation Of Fibroblast Proliferation RNA Polymerase II Preinitiation Complex Assembly Limb Development Positive Regulation Of Transcription Initiation By RNA Polymerase II
Pathways		Signaling by ALK fusions and activated point mutants	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation RSV-host interactions MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Drugs
Diseases
GWAS		Feeling guilty ( 29500382)	LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883)
Interacting Genes		12 interacting genes: CSNK1E CSNK1G1 CSNK1G2 DYNC1I1 HCK MED31 PDPK1 PRKAR1A RAB35 RPS27 TAB1 TNNT1	58 interacting genes: AGR2 ANXA7 ASCC2 CACNB4 CCT7 CDKN1A CPE DAZAP2 DLEU1 DNM1 EEF1G EGR2 EPN1 ERH FAM118B GADD45G GSTM4 HGH1 HMOX2 HNRNPUL1 HSPB1 HSPB3 HTT LAMA4 LYPLA2 MAFG MED18 MED19 MED8 MED9 MOB4 NAF1 NFATC2 NR4A1 ORAI2 PABPC4 PAFAH1B3 PFDN1 PMF1 PQBP1 PRMT1 PSMD11 RAB25 RBM23 RFC5 RPA2 SAT1 SELENBP1 SERPINB9 SMN1 TGIF1 TINAGL1 TK1 TLE5 UBE2B WDCP ZBTB45 ZSCAN1
Entrez ID		80304	51003
HPRD ID		07972	14382
Ensembl ID		ENSG00000163026	ENSG00000108590
Uniprot IDs		Q9H6R7	Q9Y3C7
PDB IDs			7EMF 7ENA 7ENC 7ENJ 7LBM 7NVR 8GXQ 8GXS 8T9D 8TQW 8TRH
Enriched GO Terms of Interacting Partners?		Cytosol Protein Kinase Activity Nucleotide Binding Protein Serine Kinase Activity Kinase Activity Positive Regulation Of Canonical Wnt Signaling Pathway Protein Phosphorylation Phosphorylation Positive Regulation Of Wnt Signaling Pathway Protein Serine/threonine Kinase Activity Endocytosis Sarcomere Organization Cellular Response To Nerve Growth Factor Stimulus Response To Nerve Growth Factor Regulation Of Canonical Wnt Signaling Pathway 3-phosphoinositide-dependent Protein Kinase Activity Slow-twitch Skeletal Muscle Fiber Contraction Cellular Response To Growth Factor Stimulus Wnt Signaling Pathway Import Into Cell Positive Regulation Of Cell Communication Vesicle-mediated Transport Positive Regulation Of Signaling Response To Growth Factor Regulation Of Wnt Signaling Pathway Cell Surface Receptor Signaling Pathway	Nucleus Core Mediator Complex Mediator Complex RNA Polymerase II Preinitiation Complex Assembly Identical Protein Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of Transcription Elongation By RNA Polymerase II Transcription Preinitiation Complex Assembly Protein Binding Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA Biosynthetic Process Regulation Of Transcription Elongation By RNA Polymerase II Positive Regulation Of DNA Metabolic Process Regulation Of Metabolic Process Positive Regulation Of DNA Biosynthetic Process Regulation Of DNA-templated Transcription Elongation Nucleoplasm
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