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C2orf44 and MED31
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
C2orf44
MED31
Gene Name
chromosome 2 open reading frame 44
mediator complex subunit 31
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Mediator Complex
Molecular Function
Kinase Binding
RNA Polymerase II Transcription Cofactor Activity
Protein Binding
Protein Complex Binding
Biological Process
Protein Oligomerization
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Protein Complex Assembly
Gene Expression
Negative Regulation Of Fibroblast Proliferation
Limb Development
Pathways
PPARA activates gene expression
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Generic Transcription Pathway
Transcriptional regulation of white adipocyte differentiation
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions
12 interactors:
CSNK1E
CSNK1G1
CSNK1G2
DYNC1I1
HCK
MED31
PDPK1
PRKAR1A
RAB35
RPS27
TAB1
TNNT1
58 interactors:
AES
AGR2
ANXA7
ASCC2
C2orf44
CACNB4
CCT7
CDKN1A
CPE
DAZAP2
DLEU1
DNM1
EEF1G
EGR2
EPN1
ERH
FAM118B
GADD45G
GSTM4
HGH1
HMOX2
HNRNPUL1
HSPB1
HSPB3
HTT
LAMA4
LYPLA2
MAFG
MED18
MED19
MED7
MED8
MED9
MOB4
NFATC2
NR4A1
ORAI2
PABPC4
PAFAH1B3
PFDN1
PMF1
PQBP1
PRMT1
PSMD11
RAB25
RBM23
RFC5
RPA2
SAT1
SELENBP1
SERPINB9
SMN1
TGIF1
TINAGL1
TK1
UBE2B
ZBTB45
ZSCAN1
Entrez ID
80304
51003
HPRD ID
07972
14382
Ensembl ID
ENSG00000163026
ENSG00000108590
Uniprot IDs
Q9H6R7
Q9Y3C7
PDB IDs
Enriched GO Terms of Interacting Partners
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Regulation Of Cell Shape
Peptidyl-serine Phosphorylation
Peptidyl-amino Acid Modification
Regulation Of Cell Morphogenesis
Phosphorylation
Cellular Response To Growth Factor Stimulus
Protein Autophosphorylation
Regulation Of Cellular Component Organization
Response To Growth Factor
Endocytosis
Protein Phosphorylation
Cell Surface Receptor Signaling Pathway
Fc Receptor Signaling Pathway
Activation Of Protein Kinase Activity
Immune System Process
Wnt Signaling Pathway
Vesicle-mediated Transport
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Peptide
Innate Immune Response
Respiratory Burst After Phagocytosis
Positive Regulation Of Phospholipase Activity
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Transport
Regulation Of Phospholipase Activity
Positive Regulation Of Lipase Activity
Leukocyte Migration Involved In Immune Response
Signal Transduction
Response To Peptide Hormone
Immune Response-regulating Signaling Pathway
Phosphate-containing Compound Metabolic Process
Positive Regulation Of Protein Kinase Activity
Cellular Response To Organic Substance
Cellular Response To Organonitrogen Compound
Response To Peptide
Positive Regulation Of Kinase Activity
Positive Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Cellular Protein Metabolic Process
Signaling
Innate Immune Response-activating Signal Transduction
Cell Communication
Mesoderm Development
Activation Of Innate Immune Response
Positive Regulation Of Transferase Activity
Respiratory Burst Involved In Defense Response
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Wnt Signaling Pathway
Cellular Response To Hormone Stimulus
Immune Response
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Gene Expression
Cellular Metabolic Process
Transcription From RNA Polymerase II Promoter
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Transcription, DNA-templated
RNA Metabolic Process
RNA Biosynthetic Process
Developmental Process
Biosynthetic Process
Regulation Of Gene Expression
Anatomical Structure Development
Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Cell Differentiation
Multicellular Organismal Development
Response To Stimulus
Neurotransmitter Uptake
Regulation Of Transcription, DNA-templated
Transcription Initiation From RNA Polymerase II Promoter
Mitotic G1 DNA Damage Checkpoint
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Nucleotide-excision Repair, DNA Gap Filling
Negative Regulation Of Apoptotic Process
Regulation Of RNA Metabolic Process
Negative Regulation Of Programmed Cell Death
Telomere Maintenance Via Semi-conservative Replication
System Development
Regulation Of Metabolic Process
Regulation Of Apoptotic Process
Negative Regulation Of Cell Death
Telomere Maintenance Via Recombination
Nuclear DNA Replication
Mitotic DNA Damage Checkpoint
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Mitotic DNA Integrity Checkpoint
Embryo Development Ending In Birth Or Egg Hatching
DNA-templated Transcription, Initiation
Response To External Stimulus
Regulation Of Cell Death
Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Cellular Protein Metabolic Process
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Tagcloud (Intersection)
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