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C2orf44 and CSNK1G2
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
C2orf44
CSNK1G2
Gene Name
chromosome 2 open reading frame 44
casein kinase 1, gamma 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytosol
Membrane
Molecular Function
Kinase Binding
Magnesium Ion Binding
Glycoprotein Binding
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Peptide Binding
Phosphoprotein Binding
Biological Process
Protein Oligomerization
Protein Phosphorylation
Sphingolipid Metabolic Process
Endocytosis
Signal Transduction
Regulation Of Cell Shape
Wnt Signaling Pathway
Peptidyl-serine Phosphorylation
Sphingolipid Biosynthetic Process
Small Molecule Metabolic Process
Protein Autophosphorylation
Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways
disassembly of the destruction complex and recruitment of AXIN to the membrane
Sphingolipid metabolism
Metabolism of lipids and lipoproteins
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
TCF dependent signaling in response to WNT
Sphingolipid de novo biosynthesis
RNF mutants show enhanced WNT signaling and proliferation
XAV939 inhibits tankyrase, stabilizing AXIN
Signaling by Wnt
Signaling by WNT in cancer
Drugs
Diseases
GWAS
Protein-Protein Interactions
12 interactors:
CSNK1E
CSNK1G1
CSNK1G2
DYNC1I1
HCK
MED31
PDPK1
PRKAR1A
RAB35
RPS27
TAB1
TNNT1
13 interactors:
APP
APPBP2
C2orf44
COL4A3BP
DBNDD2
KRTAP10-7
MTA1
NCK1
PER1
PPP1R14A
RAP1GAP
RUNDC3B
SMAD3
Entrez ID
80304
1455
HPRD ID
07972
03738
Ensembl ID
ENSG00000163026
ENSG00000133275
Uniprot IDs
Q9H6R7
P78368
PDB IDs
2C47
Enriched GO Terms of Interacting Partners
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Regulation Of Cell Shape
Peptidyl-serine Phosphorylation
Peptidyl-amino Acid Modification
Regulation Of Cell Morphogenesis
Phosphorylation
Cellular Response To Growth Factor Stimulus
Protein Autophosphorylation
Regulation Of Cellular Component Organization
Response To Growth Factor
Endocytosis
Protein Phosphorylation
Cell Surface Receptor Signaling Pathway
Fc Receptor Signaling Pathway
Activation Of Protein Kinase Activity
Immune System Process
Wnt Signaling Pathway
Vesicle-mediated Transport
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Peptide
Innate Immune Response
Respiratory Burst After Phagocytosis
Positive Regulation Of Phospholipase Activity
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Transport
Regulation Of Phospholipase Activity
Positive Regulation Of Lipase Activity
Leukocyte Migration Involved In Immune Response
Signal Transduction
Response To Peptide Hormone
Immune Response-regulating Signaling Pathway
Phosphate-containing Compound Metabolic Process
Positive Regulation Of Protein Kinase Activity
Cellular Response To Organic Substance
Cellular Response To Organonitrogen Compound
Response To Peptide
Positive Regulation Of Kinase Activity
Positive Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Cellular Protein Metabolic Process
Signaling
Innate Immune Response-activating Signal Transduction
Cell Communication
Mesoderm Development
Activation Of Innate Immune Response
Positive Regulation Of Transferase Activity
Respiratory Burst Involved In Defense Response
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Wnt Signaling Pathway
Cellular Response To Hormone Stimulus
Immune Response
Regulation Of Phosphorylation
Regulation Of Phosphorus Metabolic Process
Negative Regulation Of Phosphorylation
Posttranscriptional Regulation Of Gene Expression
Entrainment Of Circadian Clock By Photoperiod
Photoperiodism
Entrainment Of Circadian Clock
Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of Protein Metabolic Process
Regulation Of Translation
Regulation Of Inflammatory Response
Regulation Of Catalytic Activity
Negative Regulation Of Catalytic Activity
Negative Regulation Of Protein Phosphorylation
Negative Regulation Of Cellular Protein Metabolic Process
Response To Light Stimulus
Positive Regulation Of Transforming Growth Factor Beta3 Production
Positive Regulation Of Cap-dependent Translational Initiation
Positive Regulation Of Cap-independent Translational Initiation
Negative Regulation Of Microvillus Assembly
Negative Regulation Of Protein Metabolic Process
Circadian Regulation Of Gene Expression
Response To External Stimulus
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Circadian Rhythm
Positive Regulation Of Translation In Response To Stress
Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation
Synaptic Growth At Neuromuscular Junction
ER To Golgi Ceramide Transport
Positive Regulation Of Cytoplasmic Translation
Positive Regulation Of Protein Autoubiquitination
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Response To Radiation
Regulation Of Protein Phosphorylation
Response To Abiotic Stimulus
Positive Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Peptidyl-serine Dephosphorylation
Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response
Regulation Of Protein Autoubiquitination
Collateral Sprouting In Absence Of Injury
Evasion Or Tolerance Of Host Defenses By Virus
Positive Regulation Of Protein Metabolic Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway
Positive Regulation Of Extracellular Matrix Assembly
Ceramide Transport
Positive Regulation Of Peptidase Activity
Positive Regulation Of Metabolic Process
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