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C2orf44 and PRKAR1A
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
C2orf44
PRKAR1A
Gene Name
chromosome 2 open reading frame 44
protein kinase, cAMP-dependent, regulatory, type I, alpha
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Plasma Membrane
CAMP-dependent Protein Kinase Complex
Membrane
AMP-activated Protein Kinase Complex
Neuromuscular Junction
Protein Complex
Ciliary Base
Molecular Function
Kinase Binding
CAMP-dependent Protein Kinase Inhibitor Activity
Protein Binding
CAMP-dependent Protein Kinase Regulator Activity
CAMP Binding
Ubiquitin Protein Ligase Binding
Protein Kinase A Catalytic Subunit Binding
Biological Process
Protein Oligomerization
Mesoderm Formation
Renal Water Homeostasis
Energy Reserve Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Water Transport
Female Meiotic Division
Signal Transduction
Epidermal Growth Factor Receptor Signaling Pathway
Activation Of Phospholipase C Activity
Blood Coagulation
Fibroblast Growth Factor Receptor Signaling Pathway
Activation Of Protein Kinase A Activity
Intracellular Signal Transduction
Small Molecule Metabolic Process
Innate Immune Response
Sarcomere Organization
Negative Regulation Of Meiotic Nuclear Division
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Insulin Secretion
Transmembrane Transport
Cardiac Muscle Cell Proliferation
Cellular Response To Glucagon Stimulus
Negative Regulation Of CAMP-dependent Protein Kinase Activity
Pathways
Signaling by GPCR
Ca-dependent events
CaM pathway
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Hedgehog 'off' state
Integration of energy metabolism
Phospholipase C-mediated cascade
Signaling by FGFR in disease
Signaling by EGFRvIII in Cancer
PLCG1 events in ERBB2 signaling
DAG and IP3 signaling
CaM pathway
DAP12 signaling
Downstream signaling of activated FGFR
DARPP-32 events
Glucagon signaling in metabolic regulation
Innate Immune System
Signaling by PDGF
PKA activation in glucagon signalling
Calmodulin induced events
Signalling by NGF
DAP12 interactions
PKA-mediated phosphorylation of CREB
PLC beta mediated events
Vasopressin regulates renal water homeostasis via Aquaporins
Opioid Signalling
Regulation of insulin secretion
Signaling by Ligand-Responsive EGFR Variants in Cancer
NGF signalling via TRKA from the plasma membrane
G-protein mediated events
PKA activation
Factors involved in megakaryocyte development and platelet production
Signaling by Overexpressed Wild-Type EGFR in Cancer
Aquaporin-mediated transport
Signaling by FGFR
EGFR interacts with phospholipase C-gamma
Signaling by ERBB2
PKA-mediated phosphorylation of CREB
Signaling by EGFR
Downstream signal transduction
Calmodulin induced events
Signaling by Hedgehog
PLC-gamma1 signalling
Signaling by EGFR in Cancer
PKA activation
Drugs
Diseases
GWAS
Protein-Protein Interactions
12 interactors:
CSNK1E
CSNK1G1
CSNK1G2
DYNC1I1
HCK
MED31
PDPK1
PRKAR1A
RAB35
RPS27
TAB1
TNNT1
40 interactors:
AKAP1
AKAP10
AKAP11
AKAP4
AKAP7
ARFGEF2
BAHD1
C2orf44
C2orf88
CAPN11
CBS
CCNE1
CDK2
CDK4
EGFR
GRB2
HIVEP1
HLA-A
ITGA4
MAPK6
MAPT
MYO7A
NELL2
PATZ1
PJA2
PLEKHF2
PRKACA
PRKAR1B
PRKX
PRPF40A
PYCARD
RAF1
RFC2
SET
SETD7
SLC2A4
SMAD2
TAB1
WNK1
ZBED1
Entrez ID
80304
5573
HPRD ID
07972
01786
Ensembl ID
ENSG00000163026
ENSG00000108946
Uniprot IDs
Q9H6R7
B2R5T5
K7ER48
P10644
Q68DQ4
PDB IDs
Enriched GO Terms of Interacting Partners
?
Regulation Of Cell Shape
Peptidyl-serine Phosphorylation
Peptidyl-amino Acid Modification
Regulation Of Cell Morphogenesis
Phosphorylation
Cellular Response To Growth Factor Stimulus
Protein Autophosphorylation
Regulation Of Cellular Component Organization
Response To Growth Factor
Endocytosis
Protein Phosphorylation
Cell Surface Receptor Signaling Pathway
Fc Receptor Signaling Pathway
Activation Of Protein Kinase Activity
Immune System Process
Wnt Signaling Pathway
Vesicle-mediated Transport
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Peptide
Innate Immune Response
Respiratory Burst After Phagocytosis
Positive Regulation Of Phospholipase Activity
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Transport
Regulation Of Phospholipase Activity
Positive Regulation Of Lipase Activity
Leukocyte Migration Involved In Immune Response
Signal Transduction
Response To Peptide Hormone
Immune Response-regulating Signaling Pathway
Phosphate-containing Compound Metabolic Process
Positive Regulation Of Protein Kinase Activity
Cellular Response To Organic Substance
Cellular Response To Organonitrogen Compound
Response To Peptide
Positive Regulation Of Kinase Activity
Positive Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Cellular Protein Metabolic Process
Signaling
Innate Immune Response-activating Signal Transduction
Cell Communication
Mesoderm Development
Activation Of Innate Immune Response
Positive Regulation Of Transferase Activity
Respiratory Burst Involved In Defense Response
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Wnt Signaling Pathway
Cellular Response To Hormone Stimulus
Immune Response
Blood Coagulation
Hemostasis
Regulation Of Protein Kinase Activity
Regulation Of Protein Kinase A Signaling
Regulation Of Body Fluid Levels
Regulation Of Kinase Activity
Intracellular Signal Transduction
Wound Healing
Protein Phosphorylation
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
Cellular Response To Organonitrogen Compound
Response To Wounding
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
Movement Of Cell Or Subcellular Component
Phosphorylation
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Regulation Of Phosphorylation
Innate Immune Response
Cellular Response To Growth Factor Stimulus
Cellular Response To Stimulus
Regulation Of Protein Phosphorylation
Response To Stress
Response To Growth Factor
Signal Transduction
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Enzyme Linked Receptor Protein Signaling Pathway
Activation Of Protein Kinase Activity
Activation Of Phospholipase C Activity
Cell Motility
Regulation Of Phosphorus Metabolic Process
Cell Activation
Positive Regulation Of Phospholipase C Activity
Cellular Response To Organic Substance
G1/S Transition Of Mitotic Cell Cycle
Signaling
Locomotion
Cellular Response To Peptide Hormone Stimulus
Mitotic Cell Cycle
Cell Communication
Cellular Response To Peptide
Regulation Of Cellular Protein Metabolic Process
Cell Cycle
Regulation Of Catalytic Activity
Positive Regulation Of Phospholipase Activity
Heterochromatin Organization
Tagcloud
?
agouti
albinism
asip
atf1
delta25
dopachrome
edn1
edn3
ednrb
exoc2
exocyst
kitlg
ludwigshafen
mc1r
microphthalmia
oca2
oculocutaneous
pigmentation
prkacb
prkacg
proopiomelanocortin
slc24a4
slc45a2
tautomerase
tpcn2
tubb3
tyrp1
Tagcloud (Difference)
?
agouti
albinism
asip
atf1
delta25
dopachrome
edn1
edn3
ednrb
exoc2
exocyst
kitlg
ludwigshafen
mc1r
microphthalmia
oca2
oculocutaneous
pigmentation
prkacb
prkacg
proopiomelanocortin
slc24a4
slc45a2
tautomerase
tpcn2
tubb3
tyrp1
Tagcloud (Intersection)
?