RAB3IP and MVP

Number of citations of the paper that reports this interaction (PMID 24722188)
1

Data Source:
BioGRID (two hybrid)

		RAB3IP	MVP
Gene Name		RAB3A interacting protein	major vault protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Centrosome Cytosol Cytoskeleton Lamellipodium Ciliary Basal Body	Nucleus Nuclear Pore Cytoplasm Cytoskeleton Membrane Ribonucleoprotein Complex Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Rab Guanyl-nucleotide Exchange Factor Activity	Protein Binding Protein Kinase Binding Protein Phosphatase Binding
	Biological Process	Protein Targeting To Membrane Golgi To Plasma Membrane Transport Organelle Organization Positive Regulation Of Rab GTPase Activity Protein Localization To Organelle Cilium Assembly	Cell Proliferation Protein Transport Negative Regulation Of Signaling Negative Regulation Of Protein Autophosphorylation ERBB Signaling Pathway MRNA Transport Negative Regulation Of Protein Tyrosine Kinase Activity Protein Activation Cascade
Pathways		Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance VxPx cargo-targeting to cilium Assembly of the primary cilium BBSome-mediated cargo-targeting to cilium Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: BANP CHCHD3 FAM124A KRT40 MVP NAA10 PLOD3 PPL RAB3A RAB3D RAB3IL1 RAB8A RAB8B RUFY1 SFN SSX2 SUV39H2 TRAPPC6A ZNF410	57 interactors: ADAMTSL4 AES BANP BZRAP1 C1orf94 CALCOCO2 CAMK2B CCDC36 CKAP4 CYTB DISC1 DLX2 EPHX2 ESR1 FAM154A FAM46C GIT2 GOLGA2 HP KCTD9 KPNA2 KPNA3 MDFI MEOX1 MEOX2 MID2 MKL1 NNT NOTCH2NL OBFC1 PARP4 PIH1D2 PLSCR1 POT1 PSTPIP1 PTEN PTPN11 RAB3IP RBPMS REL RHOXF2 RIMBP3 RNF111 SERTAD1 SKIL SLC2A4 TCF4 TFCP2 TP53 TRAF2 TRIM27 TRIM42 TRIP13 TRIP6 VAC14 ZBTB32 ZMIZ2
Entrez ID		117177	9961
HPRD ID		10565	05475
Ensembl ID		ENSG00000127328	ENSG00000013364
Uniprot IDs		Q96QF0	B4DP93 Q14764
PDB IDs			1Y7X
Enriched GO Terms of Interacting Partners?		Synaptic Vesicle Exocytosis Rab Protein Signal Transduction Vesicle Docking Involved In Exocytosis Vesicle Docking Membrane Docking Neurotransmitter Secretion Synaptic Vesicle Transport Golgi Vesicle Fusion To Target Membrane Protein Secretion Protein Localization Regulation Of Neurotransmitter Levels Regulation Of Exocytosis Regulation Of Vesicle-mediated Transport Neurotransmitter Transport Establishment Of Vesicle Localization Vesicle Localization Ras Protein Signal Transduction Organelle Fusion Protein Transport Establishment Of Protein Localization Establishment Of Organelle Localization Exocytosis Positive Regulation Of Regulated Secretory Pathway Membrane Fusion Organelle Localization Vesicle-mediated Transport Regulation Of Regulated Secretory Pathway Secretion By Cell Vesicle Organization Keratinization Skin Development Regulation Of Cellular Localization Vesicle Fusion Synaptic Transmission Organelle Organization Regulation Of Neuronal Synaptic Plasticity Maintenance Of Presynaptic Active Zone Structure Small GTPase Mediated Signal Transduction Epidermis Development Secretion Positive Regulation Of Exocytosis Regulation Of Secretion Positive Regulation Of Secretion N-terminal Peptidyl-glutamic Acid Acetylation N-terminal Peptidyl-serine Acetylation Positive Regulation Of Transport Cellular Protein Localization Keratinocyte Differentiation Constitutive Secretory Pathway Regulation Of Synaptic Vesicle Fusion To Presynaptic Membrane	Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Regulation Of Nucleic Acid-templated Transcription Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Signaling Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Response To Cytokine RNA Metabolic Process Defense Response Positive Regulation Of Cellular Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Response To Stress Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Immune System Process Nitrogen Compound Metabolic Process Negative Regulation Of Signaling Negative Regulation Of Transcription From RNA Polymerase II Promoter Response To Organic Substance Positive Regulation Of Apoptotic Process Protein Localization To Nucleus Positive Regulation Of Programmed Cell Death Positive Regulation Of Intracellular Signal Transduction Innate Immune Response Regulation Of Intracellular Signal Transduction Cellular Metabolic Process Regulation Of Cell Death Negative Regulation Of Cellular Metabolic Process Regulation Of Catalytic Activity
Tagcloud ?		11q23 12q11 12q14 12q15 12q21 17q11 17q12 3p12 6p21 6q21 6q23 9p13 9p21 acc accs adenoid amplicons ccnd3 cnas cnot2 glipr1l1 mec mecs mucoepidermoid numa1 pax5 pvrl1 sdc statuses	afp bleomycin bronchogenic cap chance cisplatin cooperative crs cyclophosphamide doxorubicin eastern ecog efficacious entered est evaluable fluorouracil institution lethal mitomycin modest nscbc october oncology prs regimens shrinkage threatening vinblastine
Tagcloud (Difference) ?		11q23 12q11 12q14 12q15 12q21 17q11 17q12 3p12 6p21 6q21 6q23 9p13 9p21 acc accs adenoid amplicons ccnd3 cnas cnot2 glipr1l1 mec mecs mucoepidermoid numa1 pax5 pvrl1 sdc statuses	afp bleomycin bronchogenic cap chance cisplatin cooperative crs cyclophosphamide doxorubicin eastern ecog efficacious entered est evaluable fluorouracil institution lethal mitomycin modest nscbc october oncology prs regimens shrinkage threatening vinblastine
Tagcloud (Intersection) ?