DDX19B and NUP214

Number of citations of the paper that reports this interaction (PMID 10428971)
76

Data Source:
HPRD (in vitro)

		DDX19B	NUP214
Gene Name		DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B	nucleoporin 214kDa
Image
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Nuclear Pore Cytoplasm Membrane Nuclear Membrane Extracellular Vesicular Exosome	Nucleus Nuclear Pore Nucleoplasm Cytosol Focal Adhesion Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding Helicase Activity ATP Binding	Transporter Activity Nucleocytoplasmic Transporter Activity Protein Binding
	Biological Process	MRNA Export From Nucleus Protein Transport	Mitotic Cell Cycle Carbohydrate Metabolic Process MRNA Export From Nucleus Protein Import Into Nucleus Protein Export From Nucleus Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process Regulation Of Cell Cycle Transmembrane Transport
Pathways			Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport HuR stabilizes mRNA M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Regulation of mRNA stability by proteins that bind AU-rich elements Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear Pore Complex (NPC) Disassembly Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: APP B3GALT4 DCK GNB2L1 IKBKG MIF4GD NUP214 POT1 PRPSAP1 RWDD2B SKP1 TERF1 XPO7	19 interactors: APC CLEC4G DDX19B IPO5 NFX1 NUP107 NUP88 NUPL2 NXF1 NXF2 NXF3 SMAD2 SMAD3 SMAD4 TNPO1 XPO1 XPO5 XPOT ZFP36
Entrez ID		11269	8021
HPRD ID		05781	00258
Ensembl ID		ENSG00000157349	ENSG00000126883
Uniprot IDs		B4DL69 Q9UMR2	P35658
PDB IDs		3EWS 3FHC 3FHT 3FMO 3FMP 3G0H	2OIT 3FHC 3FMO 3FMP
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Negative Regulation Of Telomerase Activity Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Transferase Activity Regulation Of Telomerase Activity Negative Regulation Of Catalytic Activity Regulation Of Telomere Maintenance RNA-dependent DNA Replication Negative Regulation Of DNA Biosynthetic Process Regulation Of Catalytic Activity Telomere Maintenance Via Telomere Lengthening Viral Process Protein Export From Nucleus Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication Regulation Of Cellular Protein Metabolic Process Regulation Of Proteolysis Regulation Of Translation Positive Regulation Of Proteolysis Regulation Of Protein Tyrosine Kinase Activity Regulation Of Protein Metabolic Process Positive Regulation Of DNA Strand Elongation Telomere Maintenance Regulation Of Kinase Activity Positive Regulation Of Catalytic Activity Negative Regulation Of Chromosome Organization Regulation Of Protein Catabolic Process Synaptic Growth At Neuromuscular Junction Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Positive Regulation Of CAMP Catabolic Process Regulation Of Cell Cycle Negative Regulation Of DNA Metabolic Process Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Telomere Formation Via Telomerase Collateral Sprouting In Absence Of Injury Telomeric Loop Formation Age-dependent Telomere Shortening Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Mitotic Cell Cycle Nuclear Export MRNA Transport G2/M Transition Of Mitotic Cell Cycle Telomere Maintenance Via Telomere Shortening Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of DNA Replication Positive Regulation Of Cellular Protein Metabolic Process RNA Transport	Nucleocytoplasmic Transport Nuclear Transport Nuclear Export RNA Transport RNA Localization MRNA Transport Cytoplasmic Transport RNA Export From Nucleus Viral Process Gene Expression MRNA Export From Nucleus Establishment Of Localization In Cell Intracellular Transport Cellular Localization Protein Transport SMAD Protein Complex Assembly Establishment Of Protein Localization Gene Silencing By RNA Protein Localization Transport Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Gene Silencing Positive Regulation Of Epithelial To Mesenchymal Transition Protein Export From Nucleus Gene Silencing By MiRNA Mitotic Nuclear Envelope Disassembly Transforming Growth Factor Beta Receptor Signaling Pathway Posttranscriptional Gene Silencing Nuclear Envelope Disassembly Positive Regulation Of Stem Cell Differentiation SMAD Protein Signal Transduction Regulation Of Epithelial To Mesenchymal Transition Primary MiRNA Processing Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Regulation Of Cellular Response To Growth Factor Stimulus Viral Life Cycle Regulation Of Nucleocytoplasmic Transport Negative Regulation Of Transcription From RNA Polymerase II Promoter Nuclear Envelope Organization Somatic Stem Cell Maintenance Regulation Of Transforming Growth Factor Beta2 Production Paraxial Mesoderm Morphogenesis Poly(A)+ MRNA Export From Nucleus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Glucose Transport Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Endoderm Development Hexose Transport Embryonic Pattern Specification
Tagcloud ?			acted bona breakpoints chimeras deregulate fg fide functioned gly heterodimerization hox hoxa9 nih nucleoporin nucleoporins nup153 nup98 oncogenesis oncoproteins pbx phe physically recruit repeat repeats segments transactivation transactivators vp16
Tagcloud (Difference) ?			acted bona breakpoints chimeras deregulate fg fide functioned gly heterodimerization hox hoxa9 nih nucleoporin nucleoporins nup153 nup98 oncogenesis oncoproteins pbx phe physically recruit repeat repeats segments transactivation transactivators vp16
Tagcloud (Intersection) ?