DDX19B and EIF4G3

Number of citations of the paper that reports this interaction (PubMedID 35780119)
58

Data Source:
BioGRID (unspecified method)

		DDX19B	EIF4G3
Description		DEAD-box helicase 19B	eukaryotic translation initiation factor 4 gamma 3
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GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Pore Nucleoplasm Cytoplasm Cytoplasmic Stress Granule Membrane Extracellular Exosome	Cytosol Eukaryotic Translation Initiation Factor 4F Complex
	Molecular Function	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity MRNA Binding Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity	RNA Cap Binding RNA Binding MRNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding
	Biological Process	MRNA Export From Nucleus Poly(A)+ MRNA Export From Nucleus	Translation Translational Initiation Regulation Of Translation Regulation Of Translational Initiation Spermatid Development Negative Regulation Of Autophagy Positive Regulation Of Translation
Pathways			ISG15 antiviral mechanism
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Brain morphology (MOSTest) ( 32665545) Malaria ( 31844061) Pursuit maintenance gain ( 29064472) Systolic blood pressure ( 30578418)	Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Chronotype ( 30696823) Cognitive decline rate in late mild cognitive impairment ( 26252872) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) General risk tolerance (MTAG) ( 30643258) Mean spheric corpuscular volume ( 32888494) Morning person ( 30696823) Postoperative acute renal failure after cardiac surgery ( 30678657) Red blood cell count ( 32888494) Social science traits (pleiotropy) (HIPO component 1) ( 30289880) Superior frontal gyrus grey matter volume ( 25335168)
Interacting Genes		16 interacting genes: APP B3GALT4 CEBPA DCK EIF4G3 FOXP1 IKBKG NUP214 POT1 PRPSAP1 RACK1 RWDD2B SKP1 TERF1 UBC XPO7	17 interacting genes: CAMK1 CTNND1 DDX19B EIF4A1 EIF4E HSPB1 LIG4 LSM3 MKNK1 PABPC1 PCNT PSMB6 RNF10 TRIM25 VAV2 VPS25 WDR37
Entrez ID		11269	8672
HPRD ID		05781	06802
Ensembl ID		ENSG00000157349	ENSG00000075151
Uniprot IDs		A0A0U4B4U6 H3BQK0 Q9UMR2	A0A0A0MSA7 A0A804HJV5 A0A8I5QJH9 A0A8J9G7U8 B4DXR2 O43432 Q59GJ0
PDB IDs		3EWS 3FHC 3FHT 3FMO 3FMP 3G0H 6B4I 6B4J 6B4K	1HU3
Enriched GO Terms of Interacting Partners?		Shelterin Complex Positive Regulation Of Proteolysis Protein Homodimerization Activity Nuclear Telomere Cap Complex Telomeric Loop Disassembly Telomere Capping Telomeric D-loop Disassembly G-rich Strand Telomeric DNA Binding Nuclear Export Signal Receptor Activity Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Via Telomerase Molecular Function Activator Activity RNA-templated DNA Biosynthetic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Telomere Maintenance Via Telomere Lengthening Telomeric DNA Binding Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Antigen Receptor-mediated Signaling Pathway Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Proteolysis Positive Regulation Of Toll Signaling Pathway Nucleoplasm Regulation Of Ubiquitin-dependent Protein Catabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Telomere Maintenance Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Cytoplasmic Side Of Nuclear Pore Protein Export From Nucleus Ganglioside Galactosyltransferase Activity Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Positive Regulation Of Protein Metabolic Process Negative Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Protein Catabolic Process Identical Protein Binding Regulation Of Telomere Maintenance Via Telomere Lengthening Acetylcholine Receptor Activator Activity	Cytoplasmic Stress Granule Nucleus Cytoplasm RNA Cap Binding Eukaryotic Translation Initiation Factor 4F Complex Cytosol Calcium/calmodulin-dependent Protein Kinase Activity Extracellular Exosome RNA Binding Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Translation
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