KATNBL1 and FRS3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KATNBL1	FRS3
Description		katanin regulatory subunit B1 like 1	fibroblast growth factor receptor substrate 3
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleus Nucleoplasm Nucleolus Cytoplasm Cytoskeleton Katanin Complex Microtubule Cytoskeleton Midbody Cleavage Furrow Mitotic Spindle Mitotic Spindle Pole	Cytoplasm Plasma Membrane Membrane
	Molecular Function	Protein Binding Microtubule Binding	Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity Fibroblast Growth Factor Receptor Binding Protein Binding Identical Protein Binding
	Biological Process	Cytoplasmic Microtubule Organization Positive Regulation Of Cytoskeleton Organization	Signal Transduction Fibroblast Growth Factor Receptor Signaling Pathway
Pathways			FRS-mediated FGFR1 signaling FRS-mediated FGFR2 signaling FRS-mediated FGFR3 signaling FRS-mediated FGFR4 signaling RAF/MAP kinase cascade Activated NTRK2 signals through FRS2 and FRS3 RND2 GTPase cycle RND1 GTPase cycle Signaling by ALK fusions and activated point mutants
Drugs
Diseases
GWAS			Menarche (age at onset) ( 25231870)
Interacting Genes		39 interacting genes: CA12 CDC37 CLIC3 CPNE2 FRS3 GEM GPANK1 GUCD1 GYS1 HAP1 KAT7 KATNAL1 LMO4 LONRF1 MFAP1 MYO15B NEK6 NTAQ1 NXF1 OSGIN1 PDPK1 PFKFB1 PIBF1 POLR3C PRKAB2 PSMB1 RAD51D SCNM1 SDCBP SMARCD1 SNAPC3 TCEANC TRIM41 TUT1 ZC2HC1C ZNF329 ZNF417 ZNF572 ZNF587	112 interacting genes: ACTMAP ADAMTSL4 ANAPC11 ANKRD55 ATP23 BLZF1 BMPR2 C22orf39 CATSPER1 CBY2 CCDC33 CCN3 CDPF1 CFAP68 COL8A1 COPS3 CREB5 CYSRT1 DCDC2B DDX5 DMRT3 DPEP2NB ECM1 ESM1 FGFR1 GATA1 GPRIN2 GRB14 GRB2 HOXA1 HOXD12 ID2 ID3 IKZF3 INCA1 ISY1-RAB43 KARS1 KATNBL1 KCNJ5-AS1 KIAA0408 KPRP KRT31 KRT33B KRT34 KRT35 KRT76 KRTAP1-1 KRTAP10-8 KRTAP11-1 KRTAP3-1 KRTAP3-2 KRTAP6-2 LINGO1 LRRC18 MAPK1 MATK MBD3L1 MIIP NADSYN1 NBPF19 NOTCH2NLA NTRK1 NTRK2 NUMB PCSK5 PDLIM7 PIH1D2 PLB1 PLLP PLSCR1 POF1B PRDM6 PRKCI PTPN11 RFX6 RIMBP3C RND1 SAXO4 SCNM1 SH2B1 SHANK3 SLAIN1 SLC67A1-AS SOCS6 SPATA12 SPRY2 STH STK16 TCF4 TCP10L TGM7 TLE5 TNS1 TRAF4 TRIP6 TSC1 TSGA10IP TSPAN4 UNKL VASP VGLL3 WDR83 WWOX YPEL3 ZMIZ2 ZNF124 ZNF417 ZNF438 ZNF446 ZNF552 ZNF69 ZSCAN30
Entrez ID		79768	10817
HPRD ID		07995	06373
Ensembl ID		ENSG00000134152	ENSG00000137218
Uniprot IDs		Q9H079	A0A140VJJ7 O43559
PDB IDs			2KUP 2KUQ 2YS5 2YT2
Enriched GO Terms of Interacting Partners?			Keratin Filament Intermediate Filament Protein Binding Outer Ear Morphogenesis Structural Constituent Of Skin Epidermis Regulation Of Transcription By RNA Polymerase II Regulation Of Ossification Cellular Developmental Process Anatomical Structure Morphogenesis Structural Molecule Activity Intermediate Filament Organization Developmental Process Anatomical Structure Formation Involved In Morphogenesis Response To Growth Factor Neurotrophin Receptor Activity Neurotrophin Binding Negative Regulation Of Chondrocyte Proliferation Myelination Intermediate Filament Cytoskeleton Organization Supramolecular Fiber Organization Intermediate Filament-based Process Cell Differentiation Axon Ensheathment Cellular Response To Growth Factor Stimulus
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