BBS10 and CSNK1E

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		BBS10	CSNK1E
Gene Name		Bardet-Biedl syndrome 10	casein kinase 1, epsilon
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cilium	Nucleus Cytoplasm Cytosol Ribonucleoprotein Complex
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Protein Binding ATP Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Poly(A) RNA Binding
	Biological Process	Retina Homeostasis Visual Perception Nonmotile Primary Cilium Assembly Regulation Of Protein Complex Assembly Cellular Protein Metabolic Process Photoreceptor Cell Maintenance Response To Stimulus Chaperone-mediated Protein Complex Assembly	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle DNA Repair Protein Phosphorylation Endocytosis Organelle Organization Signal Transduction Circadian Rhythm Regulation Of Cell Shape Wnt Signaling Pathway Peptidyl-serine Phosphorylation Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Circadian Regulation Of Gene Expression Cellular Protein Localization Regulation Of Circadian Rhythm Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways		Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Assembly of the primary cilium BBSome-mediated cargo-targeting to cilium	Organelle biogenesis and maintenance misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling G2/M Transition Assembly of the primary cilium Signaling by Wnt Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane Cell Cycle, Mitotic WNT mediated activation of DVL Loss of proteins required for interphase microtubule organizationÂ from the centrosome TCF dependent signaling in response to WNT RNF mutants show enhanced WNT signaling and proliferation Loss of Nlp from mitotic centrosomes XAV939 inhibits tankyrase, stabilizing AXIN Centrosome maturation Signaling by WNT in cancer Mitotic G2-G2/M phases Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: CSNK1E FRZB HDAC6 MAP3K7 MAPK6 MAPK8IP2 NR4A1 PTK2 RASA1 RGS2 TNFSF11 YAE1D1	40 interactors: AKAP9 ANKRD6 APC APP ARHGEF1 ARNTL AXIN1 AXIN2 BBS10 BID C2orf44 CADM4 CRY1 DVL1 DVL2 DVL3 FAM110A FAM110C FAM83D FBP1 GTF3C1 HES1 KAT7 MCC NCOA3 PER1 PER2 PER3 PNO1 PPP1CA PPP1R14A RAD54B RBX1 SDCCAG3 SOCS3 TAOK1 TAZ TNS2 ZMYND8 ZNF227
Entrez ID		79738	1454
HPRD ID		08036	02919
Ensembl ID		ENSG00000179941	ENSG00000213923
Uniprot IDs		Q8TAM1	B0QY34 P49674 Q5U045
PDB IDs			4HNI 4HOK
Enriched GO Terms of Interacting Partners?		Regulation Of Signal Transduction Regulation Of Cellular Protein Metabolic Process Regulation Of Signaling Regulation Of Protein Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Catalytic Activity MAPK Cascade Signal Complex Assembly Regulation Of Cellular Component Organization Signal Transduction By Phosphorylation Cell Communication JNK Cascade Positive Regulation Of Signal Transduction Regulation Of Protein Kinase Activity Regulation Of Protein Complex Assembly Regulation Of Kinase Activity Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Cellular Response To Stimulus Positive Regulation Of Catalytic Activity Anatomical Structure Morphogenesis Regulation Of Cell Death Blood Vessel Morphogenesis Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Kinase Activity Signal Transduction Regulation Of Cell Shape Positive Regulation Of Kinase Activity Regulation Of JNK Cascade Regulation Of Intracellular Signal Transduction Regulation Of Cytoskeleton Organization Blood Vessel Development Regulation Of Protein Phosphorylation Vasculature Development Phosphorylation Negative Regulation Of Signal Transduction Intracellular Signal Transduction Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Cellular Protein Metabolic Process Signaling Positive Regulation Of Transferase Activity Negative Regulation Of Signaling Chemotaxis Response To Growth Factor Positive Regulation Of Protein Metabolic Process Regulation Of MAPK Cascade Regulation Of Cell Adhesion Cell Surface Receptor Signaling Pathway	Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Signal Transduction Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Signaling Regulation Of Wnt Signaling Pathway Regulation Of Signaling Regulation Of Signal Transduction Positive Regulation Of Wnt Signaling Pathway Regulation Of Phosphorylation Positive Regulation Of Canonical Wnt Signaling Pathway Circadian Regulation Of Gene Expression Regulation Of Phosphorus Metabolic Process Regulation Of Circadian Rhythm Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Signal Transduction Signal Transduction Regulation Of Protein Phosphorylation Regulation Of Metabolic Process Negative Regulation Of Glucocorticoid Receptor Signaling Pathway Cellular Response To Stimulus Regulation Of Intracellular Signal Transduction Wnt Signaling Pathway Signaling Regulation Of JNK Cascade Circadian Rhythm Cell Communication Canonical Wnt Signaling Pathway Regulation Of Stress-activated MAPK Cascade Planar Cell Polarity Pathway Involved In Neural Tube Closure Cochlea Development Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure Positive Regulation Of JNK Cascade Regulation Of Protein Kinase Activity Negative Regulation Of Cellular Metabolic Process Regulation Of Cellular Process Positive Regulation Of Protein Metabolic Process Regulation Of Epithelial Cell Differentiation Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Kinase Activity Regulation Of Cell Differentiation Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Response To Stimulus Wnt Signaling Pathway, Planar Cell Polarity Pathway Epithelium Development Positive Regulation Of Metabolic Process Entrainment Of Circadian Clock By Photoperiod
Tagcloud ?			accessible applicable cancerous chosen constitute crc ctnnb1 hct ihc integrated isogenic kill leave lethality msh2 pairs polb ranked rb1 rko rnai sl synergistically therapeutics top tp53 uncovering verified wnt5a
Tagcloud (Difference) ?			accessible applicable cancerous chosen constitute crc ctnnb1 hct ihc integrated isogenic kill leave lethality msh2 pairs polb ranked rb1 rko rnai sl synergistically therapeutics top tp53 uncovering verified wnt5a
Tagcloud (Intersection) ?