BBS10 and FRZB

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		BBS10	FRZB
Description		Bardet-Biedl syndrome 10	frizzled related protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cilium Cell Projection	Extracellular Region Extracellular Space Cytoplasm Membrane
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Protein Binding Wnt-protein Binding
	Biological Process	Visual Perception Intracellular Protein Localization Response To Light Stimulus Neuronal Action Potential Response To Endoplasmic Reticulum Stress Retinal Cone Cell Differentiation Regulation Of Protein-containing Complex Assembly Negative Regulation Of Neuron Apoptotic Process Photoreceptor Cell Maintenance Photoreceptor Cell Differentiation Chaperone-mediated Protein Complex Assembly Retina Development In Camera-type Eye Retinal Rod Cell Differentiation Cone Retinal Bipolar Cell Differentiation Non-motile Cilium Assembly	Skeletal System Development Epithelial Cell Development Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell Development Neural Crest Cell Differentiation Wnt Signaling Pathway Cell Differentiation Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Cell Growth Non-canonical Wnt Signaling Pathway Inner Ear Morphogenesis Positive Regulation Of Apoptotic Process Regulation Of Cell Differentiation Positive Regulation Of Fat Cell Differentiation Convergent Extension Involved In Organogenesis Canonical Wnt Signaling Pathway Negative Regulation Of Cartilage Development Somite Development Hepatocyte Differentiation Negative Regulation Of Hepatocyte Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway Cochlea Morphogenesis
Pathways		BBSome-mediated cargo-targeting to cilium
Drugs
Diseases		Bardet-Biedl syndrome (BBS)
GWAS			Blood protein levels ( 30072576) Heel bone mineral density ( 28869591 30598549) Neurological blood protein biomarker levels ( 31320639) Night sleep phenotypes ( 27126917) Waist-to-hip circumference ratio (dietary energy interaction) ( 23192594) Working memory ( 31598132)
Interacting Genes		12 interacting genes: CSNK1E FRZB HDAC6 MAP3K7 MAPK6 MAPK8IP2 NR4A1 PTK2 RASA1 RGS2 TNFSF11 YAE1	8 interacting genes: BBS10 CYSRT1 EHF ELF5 PNO1 POLA2 RBX1 SMAD1
Entrez ID		79738	2487
HPRD ID		08036	07282
Ensembl ID		ENSG00000179941	ENSG00000162998
Uniprot IDs		Q8TAM1	D9ZGF6 Q92765
PDB IDs
Enriched GO Terms of Interacting Partners?		Signal Complex Assembly JNK Cascade MAPK Cascade JUN Kinase Binding Signal Transduction Regulation Of Intracellular Signal Transduction MAP Kinase Activity Positive Regulation Of Signal Transduction Protein Phosphorylation Phosphorylation Positive Regulation Of Cell Communication Cytoplasm Regulation Of Signal Transduction Positive Regulation Of Signaling Negative Regulation Of Cell Growth Response To Amphetamine Regulation Of JNK Cascade Regulation Of Cell Communication Protein Kinase Activity Cell Surface Receptor Signaling Pathway Regulation Of Signaling Non-canonical Wnt Signaling Pathway Negative Regulation Of Hepatocyte Differentiation Regulation Of Apoptotic Process Negative Regulation Of Growth Protein Kinase Binding Positive Regulation Of Epithelial Cell Migration Ephrin Receptor Signaling Pathway Regulation Of Adenylate Cyclase-inhibiting Adrenergic Receptor Signaling Pathway Beta-tubulin Binding Response To Amine Polyubiquitinated Misfolded Protein Transport Positive Regulation Of Cholangiocyte Proliferation Anatomical Structure Morphogenesis Regulation Of Programmed Cell Death Fc Receptor Signaling Pathway Positive Regulation Of Catabolic Process Regulation Of Cell Morphogenesis Cellular Response To Growth Factor Stimulus Kinase Activity Septin Cytoskeleton Regulation Of Epithelial Cell Migration Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Glycine Import Across Plasma Membrane Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Fever Generation By Positive Regulation Of Prostaglandin Secretion Positive Regulation Of Cellular Response To Oxidative Stress Acetylspermidine Deacetylase Activity Polyamine Deacetylation Spermidine Deacetylation	Cell Fate Commitment Involved In Formation Of Primary Germ Layer
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