PHF19 and HOXB5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PHF19	HOXB5
Description		PHD finger protein 19	homeobox B5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm ESC/E(Z) Complex	Chromatin Fibrillar Center Nucleus Nucleoplasm Cytosol
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Metal Ion Binding Histone H3K4me3 Reader Activity Histone H3K36me3 Reader Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Stem Cell Population Maintenance Epigenetic Regulation Of Gene Expression Negative Regulation Of Gene Expression, Epigenetic Stem Cell Differentiation	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Anterior/posterior Pattern Specification Endothelial Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Embryonic Skeletal System Development
Pathways		PRC2 methylates histones and DNA
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Birth weight ( 27680694 31043758) Corneal astigmatism ( 29422769) High density lipoprotein cholesterol levels ( 29403010) Prostate-specific antigen levels ( 28139693) Pulse pressure ( 27618448 28135244) Refractive error ( 32231278)	Diverticular disease ( 30177863) Obesity ( 22484627)
Interacting Genes		22 interacting genes: BAG4 BTRC CSNK2A1 DVL3 H3C1 HOMEZ HOXB5 INO80E KDM1A LZTS2 PICK1 POTEB3 RCOR3 SNIP1 SUV39H1 SUV39H2 THAP1 THAP7 TSPYL2 YTHDC1 ZNF837 ZRANB1	62 interacting genes: ASB6 AXIN2 CADPS CALCOCO2 CARD9 CCDC136 CCDC88B CEP70 CNFN CSNK2B CTBP1 CTBP2 CYSRT1 GOLGA2 GOLGA6A GOLGA6L9 HAP1 HOMER3 HOOK2 HSF2BP KIFAP3 KRT31 KRT34 KRTAP1-1 KRTAP10-6 KRTAP10-8 KRTAP6-3 LDOC1 MAGEA11 MEOX2 MID2 MTUS2 NFKBID OIP5 PBX1 PBX2 PBX4 PDE4DIP PHF19 PLXND1 PRDM14 RCHY1 TBC1D26 TEKT4 TEX11 TLE5 TRAF1 TRAF2 TRAF4 TRIB3 TRIM23 TRIM27 TRIM54 USH1G VPS52 ZC4H2 ZMYND12 ZNF286A ZNF552 ZNF655 ZNF774 ZRANB1
Entrez ID		26147	3215
HPRD ID		17846	00848
Ensembl ID		ENSG00000119403	ENSG00000120075
Uniprot IDs		A0A087X169 B7Z887 B7Z8H3 F5H8K3 Q5T6S3	P09067
PDB IDs		2E5Q 4BD3 6NQ3 6WAU
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Nucleoplasm Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of DNA-templated Transcription Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of RNA Biosynthetic Process Chromatin Organization Histone H3K9 Trimethyltransferase Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Wnt Signaling Pathway Epigenetic Regulation Of Gene Expression Negative Regulation Of Macromolecule Metabolic Process Chromatin Negative Regulation Of Metabolic Process Nucleus Histone H3K9 Methyltransferase Activity Epigenetic Programming In The Zygotic Pronuclei Regulation Of DNA Repair Negative Regulation Of Macromolecule Biosynthetic Process Rhythmic Process Negative Regulation Of Biosynthetic Process Regulation Of Cell Cycle Negative Regulation Of RNA Metabolic Process Regulation Of DNA Metabolic Process Histone H3 Methyltransferase Activity Cellular Component Assembly Regulation Of Wnt Signaling Pathway Cellular Response To Decreased Oxygen Levels Epigenetic Programming Of Gene Expression Histone Methyltransferase Activity Negative Regulation Of Cell Cycle Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Response To Oxygen Levels Negative Regulation Of MRNA Modification Primary Ureteric Bud Growth Regulation Of Protein Stability Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Signal Transduction By P53 Class Mediator Chromosome Cellular Response To Glucose Starvation Regulation Of Cell Communication Regulation Of Signaling	Protein Binding Thioesterase Binding Identical Protein Binding Intermediate Filament Keratin Filament Zinc Ion Binding Cytoskeleton Tumor Necrosis Factor Receptor Binding Signaling Adaptor Activity Microtubule Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?