PHF19 and POTEB3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PHF19	POTEB3
Description		PHD finger protein 19	POTE ankyrin domain family member B3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm ESC/E(Z) Complex
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Metal Ion Binding Histone H3K4me3 Reader Activity Histone H3K36me3 Reader Activity	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Stem Cell Population Maintenance Epigenetic Regulation Of Gene Expression Negative Regulation Of Gene Expression, Epigenetic Stem Cell Differentiation
Pathways		PRC2 methylates histones and DNA
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Birth weight ( 27680694 31043758) Corneal astigmatism ( 29422769) High density lipoprotein cholesterol levels ( 29403010) Prostate-specific antigen levels ( 28139693) Pulse pressure ( 27618448 28135244) Refractive error ( 32231278)
Interacting Genes		22 interacting genes: BAG4 BTRC CSNK2A1 DVL3 H3C1 HOMEZ HOXB5 INO80E KDM1A LZTS2 PICK1 POTEB3 RCOR3 SNIP1 SUV39H1 SUV39H2 THAP1 THAP7 TSPYL2 YTHDC1 ZNF837 ZRANB1	8 interacting genes: CYP21A2 DRC4 KRTAP4-11 KRTAP4-5 KRTAP5-9 KRTAP9-2 MACO1 PHF19
Entrez ID		26147	102724631
HPRD ID		17846
Ensembl ID		ENSG00000119403	ENSG00000278522
Uniprot IDs		A0A087X169 B7Z887 B7Z8H3 F5H8K3 Q5T6S3	A0A0C4DH93 A0A0G2JQB7 A0JP26 Q495V6
PDB IDs		2E5Q 4BD3 6NQ3 6WAU
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Nucleoplasm Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of DNA-templated Transcription Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of RNA Biosynthetic Process Chromatin Organization Histone H3K9 Trimethyltransferase Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Wnt Signaling Pathway Epigenetic Regulation Of Gene Expression Negative Regulation Of Macromolecule Metabolic Process Chromatin Negative Regulation Of Metabolic Process Nucleus Histone H3K9 Methyltransferase Activity Epigenetic Programming In The Zygotic Pronuclei Regulation Of DNA Repair Negative Regulation Of Macromolecule Biosynthetic Process Rhythmic Process Negative Regulation Of Biosynthetic Process Regulation Of Cell Cycle Negative Regulation Of RNA Metabolic Process Regulation Of DNA Metabolic Process Histone H3 Methyltransferase Activity Cellular Component Assembly Regulation Of Wnt Signaling Pathway Cellular Response To Decreased Oxygen Levels Epigenetic Programming Of Gene Expression Histone Methyltransferase Activity Negative Regulation Of Cell Cycle Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Response To Oxygen Levels Negative Regulation Of MRNA Modification Primary Ureteric Bud Growth Regulation Of Protein Stability Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Signal Transduction By P53 Class Mediator Chromosome Cellular Response To Glucose Starvation Regulation Of Cell Communication Regulation Of Signaling	Intermediate Filament Keratin Filament Hair Cycle 17-hydroxyprogesterone 21-hydroxylase Activity Progesterone 21-hydroxylase Activity Steroid 21-monooxygenase Activity Cortisol Biosynthetic Process Glucocorticoid Biosynthetic Process Mineralocorticoid Biosynthetic Process Cortisol Metabolic Process Positive Regulation Of Protein Localization To Cilium Histone H3K36me3 Reader Activity Neuronal Signal Transduction Rough Endoplasmic Reticulum Membrane Regulation Of Protein Localization To Cilium Brain Development
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