PHF19

Gene Name		PHD finger protein 19
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Gene Ontology Annotations	Cellular Component	Nucleoplasm ESC/E(Z) Complex
	Molecular Function	Protein Binding Zinc Ion Binding Methylated Histone Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Gene Expression Chromatin Modification Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Histone H3-K27 Methylation
Pathways		Epigenetic regulation of gene expression PRC2 methylates histones and DNA
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: KDM1A SUV39H1 SUV39H2
Entrez ID		26147
HPRD ID		17846
Ensembl ID		ENSG00000119403
Uniprot IDs		B3KV88 F5H8K3 Q5T6S3
PDB IDs		2E5Q 4BD3
Enriched GO Terms of Interacting Partners?		Histone H3-K9 Dimethylation Histone H3-K9 Trimethylation Peptidyl-lysine Dimethylation Negative Regulation Of Circadian Rhythm Histone H3-K9 Methylation Peptidyl-lysine Trimethylation Histone Modification Histone H3-K9 Modification Chromatin Modification Chromatin Organization Negative Regulation Of Transcription From RNA Polymerase II Promoter Histone Lysine Methylation Regulation Of Circadian Rhythm Peptidyl-lysine Methylation Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Histone Methylation Chromosome Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Primitive Erythrocyte Differentiation Protein Methylation Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Peptidyl-lysine Modification Response To Hypoxia Regulation Of Transcription From RNA Polymerase II Promoter Rhythmic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Methylation Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Hormone Biosynthetic Process Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Chromatin Silencing At RDNA Granulocyte Differentiation Regulation Of Megakaryocyte Differentiation Negative Regulation Of Histone Methylation Organelle Organization RNA Metabolic Process Cellular Protein Modification Process
Tagcloud ?		aberrant astrocytoma atlas cbx6 cbx7 cbx8 diminished discovered epigenetics evolution ezh1 ezh2 gbm gbms glioblastoma interrogating malignancy multiforme overexpressed pcg phc2 polycomb progressively qrt rybp striking systematically tcga widespread