VPS37B and UBASH3B

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		VPS37B	UBASH3B
Gene Name		vacuolar protein sorting 37 homolog B (S. cerevisiae)	ubiquitin associated and SH3 domain containing B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	ESCRT I Complex Endosome Membrane Midbody Late Endosome Membrane Extracellular Vesicular Exosome	Nucleus Cytoplasm
	Molecular Function	Protein Binding Calcium-dependent Protein Binding	Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Protein Transport Viral Process Endosomal Transport Viral Life Cycle Virion Assembly Viral Protein Processing Membrane Organization Intracellular Transport Of Virus	Negative Regulation Of Protein Kinase Activity Peptidyl-tyrosine Dephosphorylation Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Platelet Aggregation
Pathways		Assembly Of The HIV Virion Synthesis And Processing Of GAG, GAGPOL Polyproteins HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Membrane binding and targetting of GAG proteins Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS			Cholesterol, total ( 20686565) HDL cholesterol ( 20686565)
Protein-Protein Interactions		15 interactors: AES BYSL CDC73 DCUN1D1 ERCC1 FBF1 NCK2 PRKAA1 QARS SH3YL1 SMARCD1 SORBS3 TSG101 UBASH3B VPS28	21 interactors: CBL CBLB DAZAP2 DMRT3 DOC2A FAM168A JAK2 KHDRBS1 PARK2 RCHY1 SLC25A48 SPRY2 SYK UBB UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2H VPS37B
Entrez ID		79720	84959
HPRD ID		07794	16463
Ensembl ID		ENSG00000139722	ENSG00000154127
Uniprot IDs		Q9H9H4	Q8TF42
PDB IDs			2CPW 2E5K
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Metabolic Process Viral Protein Processing Virion Assembly Negative Regulation Of Biosynthetic Process Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Intracellular Transport Of Virus Organelle Organization Wnt Signaling Pathway Glutaminyl-tRNA Aminoacylation Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Anatomical Structure Development Negative Regulation Of Gene Expression Regulation Of Metabolic Process Prolyl-tRNA Aminoacylation Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Post-embryonic Hemopoiesis Nucleotide-excision Repair, DNA Incision, 5'-to Lesion Nucleotide-excision Repair, DNA Incision, 3'-to Lesion Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Glucose Import In Response To Insulin Stimulus Regulation Of Organelle Organization Developmental Process Anatomical Structure Morphogenesis Response To Camptothecin Glutamyl-tRNA Aminoacylation Positive Regulation Of Anoikis Pyrimidine Dimer Repair By Nucleotide-excision Repair Negative Regulation Of Cell Cycle Posttranscriptional Regulation Of Gene Expression Response To Extracellular Stimulus Chromosome Organization Response To UV Anatomical Structure Formation Involved In Morphogenesis Response To Ionizing Radiation Regulation Of Extracellular Vesicular Exosome Assembly Endosome Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Sphingolipid Biosynthetic Process Cell Cycle Arrest Negative Regulation Of Transcription, DNA-templated Response To External Stimulus Multicellular Organismal Development Regulation Of Transcription From RNA Polymerase II Promoter Nucleotide-excision Repair, DNA Incision Late Endosome To Vacuole Transport Replicative Cell Aging Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process	Protein K48-linked Ubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Protein Catabolic Process Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Macromolecule Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Ubiquitination Positive Regulation Of Protein Modification Process Regulation Of Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Protein Modification Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Negative Regulation Of Transferase Activity Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Regulation Of Protein Metabolic Process Positive Regulation Of Transferase Activity TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Toll-like Receptor 4 Signaling Pathway Regulation Of Proteolysis Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Ubiquitin-protein Transferase Activity Protein K11-linked Ubiquitination Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Proteolysis Cellular Response To Hypoxia
Tagcloud ?			adaptor blots cooh degranulation fcepsilonri gads gamma2 grb2 ige immunoblotting immunoprecipitations lysates mast nck nonphosphorylated phosphatases phospholipase phosphorylated precipitate precipitated precipitates representing shc ship slp sts syk tula tyrosines
Tagcloud (Difference) ?			adaptor blots cooh degranulation fcepsilonri gads gamma2 grb2 ige immunoblotting immunoprecipitations lysates mast nck nonphosphorylated phosphatases phospholipase phosphorylated precipitate precipitated precipitates representing shc ship slp sts syk tula tyrosines
Tagcloud (Intersection) ?