VPS37B and FBF1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		VPS37B	FBF1
Description		VPS37B subunit of ESCRT-I	Fas binding factor 1
Image			No pdb structure
GO Annotations	Cellular Component	ESCRT I Complex Cytoplasm Endosome Plasma Membrane Endosome Membrane Membrane Midbody Late Endosome Membrane Extracellular Exosome	Spindle Pole Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Cilium Ciliary Basal Body Apical Junction Complex Keratin Filament Anchoring Junction Ciliary Transition Fiber
	Molecular Function	Protein Binding Calcium-dependent Protein Binding	Protein Binding
	Biological Process	Protein Targeting To Membrane Protein Targeting To Vacuole Protein Transport Macroautophagy Viral Release From Host Cell Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Membrane Fission Positive Regulation Of Viral Budding Via Host ESCRT Complex	Cell Projection Organization Apical Junction Assembly Cilium Assembly Establishment Of Epithelial Cell Polarity
Pathways		Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy	Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS		A body shape index ( 34021172) Hip circumference adjusted for BMI ( 34021172) Tourette syndrome ( 30818990) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Age-related hearing impairment ( 34108613) Coronary artery disease ( 29212778) White matter hyperintensities ( 30002152) White matter hyperintensity burden ( 25663218)
Interacting Genes		27 interacting genes: BAG3 BYSL CDC73 CRK DCUN1D1 ENKD1 ERCC1 EXOC8 FBF1 GORASP2 HGS KDM1A LNX1 NCK2 OSTF1 PRKAA1 PRKAA2 QARS1 SH3YL1 SMARCD1 SORBS3 TLE5 TSG101 UBASH3A UBASH3B UBC VPS28	50 interacting genes: ABI3 ACCS APP BLZF1 CALCOCO2 CCDC102B CCDC85B CEP55 CEP63 CINP CLK1 DEUP1 DGCR6 FAS FBXL12 GATA1 GCC1 GOLGA2 HIF1AN IFT20 IKZF3 KRT13 KRT31 KRT40 MEOX2 MID2 MIPOL1 PNMA1 RBPMS RHOXF2 SSX2IP SUMO1 TADA2A TASOR2 TCEA2 TEX11 TLE5 TMCC2 TRAF1 TRAF2 TRIM23 TRIM27 TRIM29 TRIM54 TSC1 TSGA10 TTC32 TUBGCP4 USHBP1 VPS37B
Entrez ID		79720	85302
HPRD ID		07794	10948
Ensembl ID		ENSG00000139722	ENSG00000188878
Uniprot IDs		Q9H9H4	Q8TES7
PDB IDs		6VME
Enriched GO Terms of Interacting Partners?		Organelle Assembly Protein Localization To Vacuole Membrane Fission Histone H2BS36 Kinase Activity [hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Ubiquitin-dependent Endocytosis Autophagy Endosome Organization Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Protein Localization To Lipid Droplet Multivesicular Body Assembly Multivesicular Body Organization Late Endosome To Vacuole Transport Negative Regulation Of Signal Transduction Negative Regulation Of Tubulin Deacetylation Negative Regulation Of Hepatocyte Apoptotic Process AMP-activated Protein Kinase Activity Endosome Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Protein Localization Organelle Organization Positive Regulation Of Protein Localization Regulation Of Tubulin Deacetylation Regulation Of Protein Modification Process Lipid Droplet Disassembly Multivesicular Body Sorting Pathway Cytoplasm Protein Localization To Lysosome Phosphatidylethanolamine Biosynthetic Process Ciliary Basal Body Regulation Of Protein Deacetylation Regulation Of Stress Granule Assembly Nucleotide-activated Protein Kinase Complex Establishment Of Protein Localization To Vacuole ESCRT I Complex Regulation Of Cellular Component Organization Protein-containing Complex Binding Positive Regulation Of Cellular Component Organization Positive Regulation Of Exosomal Secretion Regulation Of Signal Transduction Fatty Acid Homeostasis Hepatocyte Apoptotic Process Regulation Of Organelle Organization Cellular Response To Prostaglandin E Stimulus Regulation Of Exosomal Secretion Cellular Component Assembly Phosphatidylcholine Biosynthetic Process Positive Regulation Of Glycolytic Process	Identical Protein Binding Protein Binding Centriole Cytoskeleton De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation Microtubule Organizing Center Organization De Novo Centriole Assembly
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