VPS37B and ENKD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		VPS37B	ENKD1
Description		VPS37B subunit of ESCRT-I	enkurin domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	ESCRT I Complex Cytoplasm Endosome Plasma Membrane Endosome Membrane Membrane Midbody Late Endosome Membrane Extracellular Exosome	Spindle Pole Cytoplasm Centrosome Centriole Spindle Cytoskeleton Microtubule Cytoplasmic Microtubule Plasma Membrane Cilium Microtubule Cytoskeleton Ciliary Basal Body Cell Projection Ciliary Base 9+0 Non-motile Cilium
	Molecular Function	Protein Binding Calcium-dependent Protein Binding	Protein Binding Microtubule Binding Alpha-tubulin Binding
	Biological Process	Protein Targeting To Membrane Protein Targeting To Vacuole Protein Transport Macroautophagy Viral Release From Host Cell Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Membrane Fission Positive Regulation Of Viral Budding Via Host ESCRT Complex	Establishment Of Mitotic Spindle Orientation Cell Projection Organization Motile Cilium Assembly Non-motile Cilium Assembly
Pathways		Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
Drugs
Diseases
GWAS		A body shape index ( 34021172) Hip circumference adjusted for BMI ( 34021172) Tourette syndrome ( 30818990) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		27 interacting genes: BAG3 BYSL CDC73 CRK DCUN1D1 ENKD1 ERCC1 EXOC8 FBF1 GORASP2 HGS KDM1A LNX1 NCK2 OSTF1 PRKAA1 PRKAA2 QARS1 SH3YL1 SMARCD1 SORBS3 TLE5 TSG101 UBASH3A UBASH3B UBC VPS28	208 interacting genes: ABI1 ABI2 ACOT7 ACTMAP AKAP8L ANKRD23 ANKRD49 APP ARMC5 ASB3 AVPI1 BANP BCAS2 BCAS4 BCAT1 BEGAIN BEX3 BLZF1 BRAT1 C18orf54 C1orf105 CALCOCO1 CALCOCO2 CBY1 CBY2 CCDC102B CCDC13 CCDC136 CCDC28B CCDC85B CDCA4 CDPF1 CDR2 CDSN CEP55 CEP70 CHCHD3 CHRDL2 COA7 CTBP2 CYSRT1 DGCR6 DVL2 DVL3 DYDC1 ECM1 EEIG1 EFHC2 EIF4G1 EYA2 EZHIP FAM228A FAM90A1 FCHSD2 FKBP6 FOS FOSB FSD2 GADD45G GADD45GIP1 GET4 GFAP GIGYF1 GOLGA2 GOLGA6A GOLGA6L9 GPRASP3 GRHL3 GRIPAP1 HMBOX1 HNRNPH1 HOMEZ HOOK2 HOXA1 HSF2BP HSPB2 HSPB2-C11orf52 ID2 IGF1 IGFBP6 IKBKG IKZF3 JAKMIP1 KIFC3 KLHL20 KLHL26 KRT14 KRT15 KRT31 KRT35 KRT40 KRTAP10-5 KRTAP10-8 KRTAP11-1 KRTAP12-1 KRTAP13-2 KRTAP19-1 KRTAP19-5 KRTAP19-6 KRTAP4-11 KRTAP5-9 KRTAP6-2 LDOC1 LHX3 LIN7B LMO2 LRRC61 LZTS1 MAPK9 MATN4 MDFI MEIS3 MESD METTL27 MID2 MIF4GD MIPOL1 MISP MKRN3 MLH1 MORN3 MORN5 MRNIP MRPL28 MRPL38 MTUS2 MYF5 MYOZ3 N4BP3 NAB2 NBPF22P NBPF6 NCKIPSD NDUFB7 NEFL NFKBIA NHLRC4 NUTM1 OOEP PAK5 PDLIM7 PDZD4 PHC2 PIBF1 PICK1 PIK3R3 PKNOX2 PLSCR1 PNMA1 PNMA2 POLR3C PPP1CC PPP2R3C PRDM14 PRDM6 RAD54B RBCK1 RBM11 RBPMS RCN1 RUBCN RUNDC3A SLC15A2 SNRNP48 SORBS3 SPAG5 SPDEF SPSB3 SRGAP3 SSC4D STAC3 STXBP4 TENT5B TFIP11 TNNI1 TNS2 TOX2 TRAF1 TRAF2 TRAK1 TRGV7 TRIM23 TRIM27 TRIM35 TRIM54 TSC1 TSC22D4 TSEN15 UBXN11 USH1C USH1G USHBP1 USP20 VBP1 VPS37B VWC2 WDR62 WWOX YWHAE ZBTB14 ZC2HC1C ZFP90 ZNF143 ZNF426 ZNF511 ZNF581 ZNF76 ZRANB1
Entrez ID		79720	84080
HPRD ID		07794	13151
Ensembl ID		ENSG00000139722	ENSG00000124074
Uniprot IDs		Q9H9H4	Q9H0I2
PDB IDs		6VME
Enriched GO Terms of Interacting Partners?		Organelle Assembly Protein Localization To Vacuole Membrane Fission Histone H2BS36 Kinase Activity [hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Ubiquitin-dependent Endocytosis Autophagy Endosome Organization Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Protein Localization To Lipid Droplet Multivesicular Body Assembly Multivesicular Body Organization Late Endosome To Vacuole Transport Negative Regulation Of Signal Transduction Negative Regulation Of Tubulin Deacetylation Negative Regulation Of Hepatocyte Apoptotic Process AMP-activated Protein Kinase Activity Endosome Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Protein Localization Organelle Organization Positive Regulation Of Protein Localization Regulation Of Tubulin Deacetylation Regulation Of Protein Modification Process Lipid Droplet Disassembly Multivesicular Body Sorting Pathway Cytoplasm Protein Localization To Lysosome Phosphatidylethanolamine Biosynthetic Process Ciliary Basal Body Regulation Of Protein Deacetylation Regulation Of Stress Granule Assembly Nucleotide-activated Protein Kinase Complex Establishment Of Protein Localization To Vacuole ESCRT I Complex Regulation Of Cellular Component Organization Protein-containing Complex Binding Positive Regulation Of Cellular Component Organization Positive Regulation Of Exosomal Secretion Regulation Of Signal Transduction Fatty Acid Homeostasis Hepatocyte Apoptotic Process Regulation Of Organelle Organization Cellular Response To Prostaglandin E Stimulus Regulation Of Exosomal Secretion Cellular Component Assembly Phosphatidylcholine Biosynthetic Process Positive Regulation Of Glycolytic Process	Protein Binding Intermediate Filament Identical Protein Binding Keratin Filament Cytoskeleton Cytosol Intermediate Filament Organization Nucleus Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization
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