UBASH3B and FAM168A

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		UBASH3B	FAM168A
Gene Name		ubiquitin associated and SH3 domain containing B	family with sequence similarity 168, member A
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Negative Regulation Of Protein Kinase Activity Peptidyl-tyrosine Dephosphorylation Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Platelet Aggregation
Pathways
Drugs
Diseases
GWAS		Cholesterol, total ( 20686565) HDL cholesterol ( 20686565)	Pulmonary function (interaction) ( 23284291)
Protein-Protein Interactions		21 interactors: CBL CBLB DAZAP2 DMRT3 DOC2A FAM168A JAK2 KHDRBS1 PARK2 RCHY1 SLC25A48 SPRY2 SYK UBB UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2H VPS37B	22 interactors: C1orf94 CALCOCO2 DAB1 DAZAP2 DTX2 KLHL42 NAF1 OTUB2 OTULIN PRR20A R3HDM2 RBFOX1 RBPMS SF1 SMAP2 SNRPC SS18L1 TAX1BP1 TNIP1 UBASH3B UBE2V1 VPS37C
Entrez ID		84959	23201
HPRD ID		16463	13792
Ensembl ID		ENSG00000154127	ENSG00000054965
Uniprot IDs		Q8TF42	Q92567
PDB IDs		2CPW 2E5K
Enriched GO Terms of Interacting Partners?		Protein K48-linked Ubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Protein Catabolic Process Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Macromolecule Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Ubiquitination Positive Regulation Of Protein Modification Process Regulation Of Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Protein Modification Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Negative Regulation Of Transferase Activity Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Regulation Of Protein Metabolic Process Positive Regulation Of Transferase Activity TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Toll-like Receptor 4 Signaling Pathway Regulation Of Proteolysis Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Ubiquitin-protein Transferase Activity Protein K11-linked Ubiquitination Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Proteolysis Cellular Response To Hypoxia	Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response Intracellular Receptor Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Innate Immune Response Toll-like Receptor Signaling Pathway Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Defense Response Immune Response-regulating Signaling Pathway Gene Expression Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway MRNA Splice Site Selection Regulation Of RNA Metabolic Process Negative Regulation Of Viral Genome Replication Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling RNA Processing Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Protein Linear Deubiquitination Error-free Postreplication DNA Repair Negative Regulation Of ERK1 And ERK2 Cascade Spliceosomal Complex Assembly Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Gene Expression Positive Regulation Of Immune Response Regulation Of Inflammatory Response Regulation Of Nitrogen Compound Metabolic Process Regulation Of Viral Genome Replication Negative Regulation Of Viral Process Cerebellum Structural Organization Ribonucleoprotein Complex Biogenesis Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Metabolic Process RNA Splicing Regulation Of Nucleic Acid-templated Transcription Regulation Of Metabolic Process Regulation Of RNA Biosynthetic Process Cellular Protein Metabolic Process Regulation Of Phosphorylation Lateral Motor Column Neuron Migration Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Inflammatory Response Cellular Metabolic Process Innate Immune Response Interaction With Host
Tagcloud ?		adaptor blots cooh degranulation fcepsilonri gads gamma2 grb2 ige immunoblotting immunoprecipitations lysates mast nck nonphosphorylated phosphatases phospholipase phosphorylated precipitate precipitated precipitates representing shc ship slp sts syk tula tyrosines
Tagcloud (Difference) ?		adaptor blots cooh degranulation fcepsilonri gads gamma2 grb2 ige immunoblotting immunoprecipitations lysates mast nck nonphosphorylated phosphatases phospholipase phosphorylated precipitate precipitated precipitates representing shc ship slp sts syk tula tyrosines
Tagcloud (Intersection) ?