VPS37B and SH3YL1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		VPS37B	SH3YL1
Gene Name		vacuolar protein sorting 37 homolog B (S. cerevisiae)	SH3 and SYLF domain containing 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	ESCRT I Complex Endosome Membrane Midbody Late Endosome Membrane Extracellular Vesicular Exosome	Ruffle Membrane
	Molecular Function	Protein Binding Calcium-dependent Protein Binding	Phosphatase Binding Phosphatidylinositol Binding
	Biological Process	Protein Transport Viral Process Endosomal Transport Viral Life Cycle Virion Assembly Viral Protein Processing Membrane Organization Intracellular Transport Of Virus	Phosphatidylinositol Biosynthetic Process Regulation Of Ruffle Assembly
Pathways		Assembly Of The HIV Virion Synthesis And Processing Of GAG, GAGPOL Polyproteins HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Membrane binding and targetting of GAG proteins Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: AES BYSL CDC73 DCUN1D1 ERCC1 FBF1 NCK2 PRKAA1 QARS SH3YL1 SMARCD1 SORBS3 TSG101 UBASH3B VPS28	7 interactors: GFAP HELZ KHDRBS1 SH3D19 VIM VPS37B ZBTB7B
Entrez ID		79720	26751
HPRD ID		07794	15336
Ensembl ID		ENSG00000139722	ENSG00000035115
Uniprot IDs		Q9H9H4	Q96HL8
PDB IDs			2D8H
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Metabolic Process Viral Protein Processing Virion Assembly Negative Regulation Of Biosynthetic Process Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Intracellular Transport Of Virus Organelle Organization Wnt Signaling Pathway Glutaminyl-tRNA Aminoacylation Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Anatomical Structure Development Negative Regulation Of Gene Expression Regulation Of Metabolic Process Prolyl-tRNA Aminoacylation Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Post-embryonic Hemopoiesis Nucleotide-excision Repair, DNA Incision, 5'-to Lesion Nucleotide-excision Repair, DNA Incision, 3'-to Lesion Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Glucose Import In Response To Insulin Stimulus Regulation Of Organelle Organization Developmental Process Anatomical Structure Morphogenesis Response To Camptothecin Glutamyl-tRNA Aminoacylation Positive Regulation Of Anoikis Pyrimidine Dimer Repair By Nucleotide-excision Repair Negative Regulation Of Cell Cycle Posttranscriptional Regulation Of Gene Expression Response To Extracellular Stimulus Chromosome Organization Response To UV Anatomical Structure Formation Involved In Morphogenesis Response To Ionizing Radiation Regulation Of Extracellular Vesicular Exosome Assembly Endosome Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Sphingolipid Biosynthetic Process Cell Cycle Arrest Negative Regulation Of Transcription, DNA-templated Response To External Stimulus Multicellular Organismal Development Regulation Of Transcription From RNA Polymerase II Promoter Nucleotide-excision Repair, DNA Incision Late Endosome To Vacuole Transport Replicative Cell Aging Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process	Bergmann Glial Cell Differentiation Intermediate Filament Organization Astrocyte Development Intermediate Filament Cytoskeleton Organization Astrocyte Differentiation Intermediate Filament-based Process Positive Regulation Of Schwann Cell Proliferation Glial Cell Development Negative Regulation Of Neuron Projection Development Positive Regulation Of RNA Export From Nucleus Negative Regulation Of Cell Projection Organization Glial Cell Differentiation Negative Regulation Of Neuron Differentiation Gliogenesis Negative Regulation Of Neurogenesis Viral Protein Processing Cytoskeleton Organization Regulation Of RNA Export From Nucleus Negative Regulation Of Cell Development Positive Regulation Of Glial Cell Proliferation Regulation Of Neurotransmitter Uptake Positive Regulation Of Membrane Protein Ectodomain Proteolysis Positive Regulation Of Translational Initiation Regulation Of Neuron Projection Development Lens Fiber Cell Development Virion Assembly Ectoderm Development Regulation Of Cell Projection Organization Intracellular Transport Of Virus
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