SAP30L and FEZ2

Number of citations of the paper that reports this interaction (PubMedID 16484223)
0

Data Source:
BioGRID (two hybrid)

		SAP30L	FEZ2
Description		SAP30 like	fasciculation and elongation protein zeta 2
Image			No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Fibrillar Center Nucleus Nucleoplasm Nucleolus Sin3-type Complex	Cytoplasm Axon
	Molecular Function	DNA Binding Transcription Coregulator Activity Protein Binding Zinc Ion Binding Lipid Binding Phosphatidylinositol-5-phosphate Binding Nucleosome Binding Phosphatidylinositol-3-phosphate Binding Histone Binding Non-sequence-specific DNA Binding, Bending Metal Ion Binding Phosphatidylinositol-4-phosphate Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance	Signal Transduction Nervous System Development Axon Guidance Negative Regulation Of Autophagosome Assembly
Pathways		HDACs deacetylate histones NoRC negatively regulates rRNA expression Potential therapeutics for SARS
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Angiotensin-converting enzyme inhibitor intolerance ( 28030426) QRS duration ( 25035420)	Apolipoprotein A1 levels ( 32203549) Haemorrhoidal disease ( 33888516) Hip circumference adjusted for BMI ( 34021172) Intraocular pressure ( 29617998) Metabolite levels ( 23823483) Offspring birth weight ( 31043758) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		4 interacting genes: DVL3 FEZ1 FEZ2 HMBOX1	18 interacting genes: BRD1 CLASP2 DRAP1 FEZ1 KPNA2 NEK1 PDCD7 PRKCZ RAB3GAP1 RAI14 SAP30L SMC3 STIP1 TBC1D25 TEDC2 TLK2 WWC1 ZNF251
Entrez ID		79685	9637
HPRD ID		08563	09213
Ensembl ID		ENSG00000164576	ENSG00000171055
Uniprot IDs		Q9HAJ7	Q9UHY8
PDB IDs		2N1U
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Autophagosome Assembly Negative Regulation Of Macroautophagy Regulation Of Autophagosome Assembly Regulation Of Vacuole Organization Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Telomere-telomerase Complex Assembly Negative Regulation Of Autophagy Regulation Of Macroautophagy Axon Guidance Neuron Projection Guidance Positive Regulation Of Neuron Projection Arborization Regulation Of Organelle Assembly Regulation Of Organelle Transport Along Microtubule Double-stranded Telomeric DNA Binding Regulation Of Organelle Organization Regulation Of Neuron Projection Arborization Positive Regulation Of Cell Projection Organization Regulation Of Autophagy Negative Regulation Of Catabolic Process Polypeptide N-acetylgalactosaminyltransferase Activity Axon	Establishment Or Maintenance Of Cell Polarity Establishment Of Cell Polarity
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