SAP30L

Description		SAP30 like
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GO Annotations	Cellular Component	Histone Deacetylase Complex Fibrillar Center Nucleus Nucleoplasm Nucleolus Sin3-type Complex
	Molecular Function	DNA Binding Transcription Coregulator Activity Protein Binding Zinc Ion Binding Lipid Binding Phosphatidylinositol-5-phosphate Binding Nucleosome Binding Phosphatidylinositol-3-phosphate Binding Histone Binding Non-sequence-specific DNA Binding, Bending Metal Ion Binding Phosphatidylinositol-4-phosphate Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance
Pathways		HDACs deacetylate histones NoRC negatively regulates rRNA expression Potential therapeutics for SARS
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Angiotensin-converting enzyme inhibitor intolerance ( 28030426) QRS duration ( 25035420)
Novel Interacting Genes		1 novel interacting genes: GALNT10
Interacting Genes		4 interacting genes: DVL3 FEZ1 FEZ2 HMBOX1
Entrez ID		79685
HPRD ID		08563
Ensembl ID		ENSG00000164576
Uniprot IDs		Q9HAJ7
PDB IDs		2N1U
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Autophagosome Assembly Negative Regulation Of Macroautophagy Regulation Of Autophagosome Assembly Regulation Of Vacuole Organization Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Telomere-telomerase Complex Assembly Negative Regulation Of Autophagy Regulation Of Macroautophagy Axon Guidance Neuron Projection Guidance Positive Regulation Of Neuron Projection Arborization Regulation Of Organelle Assembly Regulation Of Organelle Transport Along Microtubule Double-stranded Telomeric DNA Binding Regulation Of Organelle Organization Regulation Of Neuron Projection Arborization Positive Regulation Of Cell Projection Organization Regulation Of Autophagy Negative Regulation Of Catabolic Process Polypeptide N-acetylgalactosaminyltransferase Activity Axon
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