AIMP2 and GYS1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		AIMP2	GYS1
Gene Name		aminoacyl tRNA synthetase complex-interacting multifunctional protein 2	glycogen synthase 1 (muscle)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Membrane	Cytoplasm Cytosol Membrane Inclusion Body
	Molecular Function	Protein Binding	Glycogen (starch) Synthase Activity Protein Binding Glucose Binding Protein Kinase Binding Glycogen Synthase Activity, Transferring Glucose-1-phosphate
	Biological Process	TRNA Aminoacylation For Protein Translation Apoptotic Process Negative Regulation Of Cell Proliferation Gene Expression Positive Regulation Of Protein Ubiquitination Type II Pneumocyte Differentiation	Carbohydrate Metabolic Process Glycogen Biosynthetic Process Glucose Metabolic Process Heart Development Pathogenesis Small Molecule Metabolic Process
Pathways		Cytosolic tRNA aminoacylation tRNA Aminoacylation	Glucose metabolism Glycogen synthesis Myoclonic epilepsy of Lafora Glycogen storage diseases Metabolism of carbohydrates
Drugs
Diseases
GWAS
Protein-Protein Interactions		48 interactors: ACTB AIMP1 APP BCAS2 BLOC1S4 BYSL C19orf57 CEP170P1 CHD3 DARS DARS2 DEAF1 DSN1 EPRS EPS8 FGB FHL3 FUBP1 GYS1 ICE1 KARS KDR KIAA1377 KLC2 LMO2 LMO3 LNX1 LUC7L2 MATR3 MCF2L MIS18A NDEL1 NECAB2 NGFRAP1 PARK2 PCMT1 PLEKHF2 PPP2R1A PRKAA2 PSME1 TANK TERF2IP TFIP11 TP53 TRAF2 TRMT2A ZC3H12A ZGPAT	9 interactors: AIMP2 APP CCDC36 CSNK2A1 GSK3B GYG1 GYG2 MAPKAPK5 PRKACA
Entrez ID		7965	2997
HPRD ID		02915	00721
Ensembl ID		ENSG00000106305	ENSG00000104812
Uniprot IDs		A8MU58 Q13155	P13807
PDB IDs		4DPG
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Component Assembly TRNA Aminoacylation For Protein Translation Axon Cargo Transport TRNA Aminoacylation Cell Cycle Process NcRNA Metabolic Process Mitotic Cell Cycle Process Positive Regulation Of Cellular Metabolic Process Regulation Of Autophagy Mitotic Cell Cycle Apoptotic Process Platelet Aggregation Negative Regulation Of Reactive Oxygen Species Metabolic Process Programmed Cell Death Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Regulation Of Mitochondrion Degradation Protein Complex Assembly Microtubule-based Transport Immune System Process Cell Death Death TRNA Metabolic Process Cellular Response To Organic Substance Cytoskeleton-dependent Intracellular Transport Blood Coagulation Cell Cycle Cellular Macromolecule Biosynthetic Process Hemostasis Positive Regulation Of Peptidase Activity Macromolecule Biosynthetic Process Cellular Process Cellular Amino Acid Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Proteolysis Positive Regulation Of Metabolic Process Regulation Of Intracellular Signal Transduction Regulation Of Apoptotic Process Cellular Metabolic Process Response To Wounding Regulation Of Signaling Regulation Of Cellular Ketone Metabolic Process See more	Energy Reserve Metabolic Process Positive Regulation Of Protein Metabolic Process Glycogen Metabolic Process Energy Derivation By Oxidation Of Organic Compounds Polysaccharide Metabolic Process Apoptotic Process Generation Of Precursor Metabolites And Energy Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Export From Nucleus Cell Death Death Positive Regulation Of Cellular Protein Metabolic Process Glucose Metabolic Process Regulation Of Protein Binding Glycogen Catabolic Process Carbohydrate Biosynthetic Process Regulation Of Protein Metabolic Process Polysaccharide Catabolic Process Protein Phosphorylation Chemotaxis Regulation Of Proteasomal Protein Catabolic Process Glycogen Biosynthetic Process Pathogenesis Hexose Metabolic Process Regulation Of Proteolysis Regulation Of Cardiac Muscle Hypertrophy Regulation Of Protein Export From Nucleus Cellular Carbohydrate Catabolic Process Cellular Carbohydrate Metabolic Process Regulation Of Protein Kinase Activity Monosaccharide Metabolic Process Regulation Of Binding Negative Regulation Of Catalytic Activity Cellular Polysaccharide Biosynthetic Process Regulation Of Kinase Activity Negative Regulation Of Cellular Protein Metabolic Process Polysaccharide Biosynthetic Process Regulation Of MAP Kinase Activity Negative Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Phosphorylation Positive Regulation Of Metabolic Process Carbohydrate Metabolic Process Regulation Of Protein Catabolic Process Axon Guidance Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Protein Phosphorylation Regulation Of Protein Processing Regulation Of Mitotic Cell Cycle See more
Tagcloud ?		4x20 abl abrogated bbb c57 compacts dopaminergic e3 easily endothelium inno irreversible microvessel mitigated mptp nanomolar neurodegeneration neuroprotective nigra nitrative parkin pars pd pharmacokinetic striatum substantia th translated ubiquitously	akt1 antidiabetic antiobesity extract fructose glut glut1 glut2 glut3 glut4 green gsk3b igf1 igf2 igf2r ins1 ins2 insr irs1 irs2 pik3cb pik3r1 shc1 slc2a1 slc2a2 slc2a3 slc2a4 sos1 tea
Tagcloud (Difference) ?		4x20 abl abrogated bbb c57 compacts dopaminergic e3 easily endothelium inno irreversible microvessel mitigated mptp nanomolar neurodegeneration neuroprotective nigra nitrative parkin pars pd pharmacokinetic striatum substantia th translated ubiquitously	akt1 antidiabetic antiobesity extract fructose glut glut1 glut2 glut3 glut4 green gsk3b igf1 igf2 igf2r ins1 ins2 insr irs1 irs2 pik3cb pik3r1 shc1 slc2a1 slc2a2 slc2a3 slc2a4 sos1 tea
Tagcloud (Intersection) ?