AIMP2 and DEAF1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		AIMP2	DEAF1
Gene Name		aminoacyl tRNA synthetase complex-interacting multifunctional protein 2	DEAF1 transcription factor
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Membrane	Extracellular Region Nucleus Nucleoplasm Transcription Factor Complex Nucleolus Cytoplasm
	Molecular Function	Protein Binding	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Apoptotic Process Negative Regulation Of Cell Proliferation Gene Expression Positive Regulation Of Protein Ubiquitination Type II Pneumocyte Differentiation	Behavioral Fear Response Neural Tube Closure Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Germ Cell Development Visual Learning Anatomical Structure Morphogenesis Regulation Of Mammary Gland Epithelial Cell Proliferation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Embryonic Skeletal System Development
Pathways		Cytosolic tRNA aminoacylation tRNA Aminoacylation
Drugs
Diseases
GWAS
Protein-Protein Interactions		48 interactors: ACTB AIMP1 APP BCAS2 BLOC1S4 BYSL C19orf57 CEP170P1 CHD3 DARS DARS2 DEAF1 DSN1 EPRS EPS8 FGB FHL3 FUBP1 GYS1 ICE1 KARS KDR KIAA1377 KLC2 LMO2 LMO3 LNX1 LUC7L2 MATR3 MCF2L MIS18A NDEL1 NECAB2 NGFRAP1 PARK2 PCMT1 PLEKHF2 PPP2R1A PRKAA2 PSME1 TANK TERF2IP TFIP11 TP53 TRAF2 TRMT2A ZC3H12A ZGPAT	18 interactors: AIMP2 ASCC2 CDC37 CDKN1A CDKN2A FHL1 GSK3A GSK3B HRAS HRSP12 INTS1 LMO4 PELI2 PIN1 PPP1CA PPP1CC RAD23B TK1
Entrez ID		7965	10522
HPRD ID		02915	04027
Ensembl ID		ENSG00000106305	ENSG00000177030
Uniprot IDs		A8MU58 Q13155	O75398
PDB IDs		4DPG	2JW6 4A24
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Component Assembly TRNA Aminoacylation For Protein Translation Axon Cargo Transport TRNA Aminoacylation Cell Cycle Process NcRNA Metabolic Process Mitotic Cell Cycle Process Positive Regulation Of Cellular Metabolic Process Regulation Of Autophagy Mitotic Cell Cycle Apoptotic Process Platelet Aggregation Negative Regulation Of Reactive Oxygen Species Metabolic Process Programmed Cell Death Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Regulation Of Mitochondrion Degradation Protein Complex Assembly Microtubule-based Transport Immune System Process Cell Death Death TRNA Metabolic Process Cellular Response To Organic Substance Cytoskeleton-dependent Intracellular Transport Blood Coagulation Cell Cycle Cellular Macromolecule Biosynthetic Process Hemostasis Positive Regulation Of Peptidase Activity Macromolecule Biosynthetic Process Cellular Process Cellular Amino Acid Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Proteolysis Positive Regulation Of Metabolic Process Regulation Of Intracellular Signal Transduction Regulation Of Apoptotic Process Cellular Metabolic Process Response To Wounding Regulation Of Signaling Regulation Of Cellular Ketone Metabolic Process	Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Glycogen Metabolic Process Positive Regulation Of Protein Modification Process Polysaccharide Metabolic Process Regulation Of Protein Phosphorylation Negative Regulation Of Type B Pancreatic Cell Development Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Cellular Senescence Regulation Of Glycogen Biosynthetic Process Regulation Of Phosphorylation Cellular Response To Growth Factor Stimulus Hypermethylation Of CpG Island Energy Reserve Metabolic Process Regulation Of Glycogen Metabolic Process Response To Growth Factor Regulation Of Cellular Component Organization Apoptotic Process Regulation Of Cell Growth Negative Regulation Of Cell Growth Cellular Response To Interleukin-3 Programmed Cell Death Regulation Of Phosphorus Metabolic Process Cellular Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cell Death Death Tube Development Negative Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Protein Phosphorylation Regulation Of Mitotic Cell Cycle Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of Protein Kinase Activity Response To Fibroblast Growth Factor Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Neurotrophin TRK Receptor Signaling Pathway Innate Immune Response Immune Response-regulating Signaling Pathway Neurotrophin Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cell Aging Fc-epsilon Receptor Signaling Pathway Regulation Of Generation Of Precursor Metabolites And Energy Cellular Carbohydrate Metabolic Process Negative Regulation Of Cardiac Muscle Hypertrophy
Tagcloud ?		4x20 abl abrogated bbb c57 compacts dopaminergic e3 easily endothelium inno irreversible microvessel mitigated mptp nanomolar neurodegeneration neuroprotective nigra nitrative parkin pars pd pharmacokinetic striatum substantia th translated ubiquitously	abundantly believed carcinomas cardiomyocyte dysfunction enhancer epigenetic gather growing interest list making methylate myeloid mynd myogenesis nervy putative regulator relevance remodeling skeletal smyd suppressor transduction trithorax variegation variety zeste
Tagcloud (Difference) ?		4x20 abl abrogated bbb c57 compacts dopaminergic e3 easily endothelium inno irreversible microvessel mitigated mptp nanomolar neurodegeneration neuroprotective nigra nitrative parkin pars pd pharmacokinetic striatum substantia th translated ubiquitously	abundantly believed carcinomas cardiomyocyte dysfunction enhancer epigenetic gather growing interest list making methylate myeloid mynd myogenesis nervy putative regulator relevance remodeling skeletal smyd suppressor transduction trithorax variegation variety zeste
Tagcloud (Intersection) ?