AIMP2 and DARS2

Number of citations of the paper that reports this interaction (PMID 9878398)
36

Data Source:
BioGRID (two hybrid)

		AIMP2	DARS2
Gene Name		aminoacyl tRNA synthetase complex-interacting multifunctional protein 2	aspartyl-tRNA synthetase 2, mitochondrial
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Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Membrane	Nucleus Nucleoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	Protein Binding	TRNA Binding Aspartate-tRNA Ligase Activity Protein Binding ATP Binding Protein Homodimerization Activity Aspartate-tRNA(Asn) Ligase Activity
	Biological Process	TRNA Aminoacylation For Protein Translation Apoptotic Process Negative Regulation Of Cell Proliferation Gene Expression Positive Regulation Of Protein Ubiquitination Type II Pneumocyte Differentiation	TRNA Aminoacylation For Protein Translation Gene Expression TRNA Aminoacylation Mitochondrial Asparaginyl-tRNA Aminoacylation
Pathways		Cytosolic tRNA aminoacylation tRNA Aminoacylation	tRNA Aminoacylation Mitochondrial tRNA aminoacylation
Drugs
Diseases
GWAS
Protein-Protein Interactions		48 interactors: ACTB AIMP1 APP BCAS2 BLOC1S4 BYSL C19orf57 CEP170P1 CHD3 DARS DARS2 DEAF1 DSN1 EPRS EPS8 FGB FHL3 FUBP1 GYS1 ICE1 KARS KDR KIAA1377 KLC2 LMO2 LMO3 LNX1 LUC7L2 MATR3 MCF2L MIS18A NDEL1 NECAB2 NGFRAP1 PARK2 PCMT1 PLEKHF2 PPP2R1A PRKAA2 PSME1 TANK TERF2IP TFIP11 TP53 TRAF2 TRMT2A ZC3H12A ZGPAT	4 interactors: AIMP2 DPYSL5 EPHA8 KARS
Entrez ID		7965	55157
HPRD ID		02915	07677
Ensembl ID		ENSG00000106305	ENSG00000117593
Uniprot IDs		A8MU58 Q13155	Q6PI48 Q9H9J7
PDB IDs		4DPG	4AH6
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Component Assembly TRNA Aminoacylation For Protein Translation Axon Cargo Transport TRNA Aminoacylation Cell Cycle Process NcRNA Metabolic Process Mitotic Cell Cycle Process Positive Regulation Of Cellular Metabolic Process Regulation Of Autophagy Mitotic Cell Cycle Apoptotic Process Platelet Aggregation Negative Regulation Of Reactive Oxygen Species Metabolic Process Programmed Cell Death Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Regulation Of Mitochondrion Degradation Protein Complex Assembly Microtubule-based Transport Immune System Process Cell Death Death TRNA Metabolic Process Cellular Response To Organic Substance Cytoskeleton-dependent Intracellular Transport Blood Coagulation Cell Cycle Cellular Macromolecule Biosynthetic Process Hemostasis Positive Regulation Of Peptidase Activity Macromolecule Biosynthetic Process Cellular Process Cellular Amino Acid Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Proteolysis Positive Regulation Of Metabolic Process Regulation Of Intracellular Signal Transduction Regulation Of Apoptotic Process Cellular Metabolic Process Response To Wounding Regulation Of Signaling Regulation Of Cellular Ketone Metabolic Process	TRNA Aminoacylation For Protein Translation TRNA Aminoacylation Lysyl-tRNA Aminoacylation Diadenosine Tetraphosphate Biosynthetic Process TRNA Metabolic Process Type II Pneumocyte Differentiation Pyrimidine Nucleobase Catabolic Process Neuron Remodeling Axon Guidance Lung Secretory Cell Differentiation Cellular Amino Acid Metabolic Process NcRNA Metabolic Process Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Small Molecule Metabolic Process Chemotaxis Neuron Projection Morphogenesis Nucleobase-containing Small Molecule Metabolic Process Translation Positive Regulation Of Phosphatidylinositol 3-kinase Activity Neuron Maturation Cell Morphogenesis Involved In Differentiation Substrate-dependent Cell Migration Pyrimidine Nucleobase Metabolic Process Regulation Of Cell Adhesion Mediated By Integrin Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Regulation Of Phosphatidylinositol 3-kinase Activity Neuron Development Lung Epithelial Cell Differentiation Regulation Of Lipid Kinase Activity Carboxylic Acid Metabolic Process Lung Cell Differentiation Cell Differentiation Cell Morphogenesis Lung Epithelium Development Neuron Differentiation Organic Acid Metabolic Process Cell Projection Organization Locomotion Ephrin Receptor Signaling Pathway
Tagcloud ?		4x20 abl abrogated bbb c57 compacts dopaminergic e3 easily endothelium inno irreversible microvessel mitigated mptp nanomolar neurodegeneration neuroprotective nigra nitrative parkin pars pd pharmacokinetic striatum substantia th translated ubiquitously
Tagcloud (Difference) ?		4x20 abl abrogated bbb c57 compacts dopaminergic e3 easily endothelium inno irreversible microvessel mitigated mptp nanomolar neurodegeneration neuroprotective nigra nitrative parkin pars pd pharmacokinetic striatum substantia th translated ubiquitously
Tagcloud (Intersection) ?