CORO7 and EPS15

Number of citations of the paper that reports this interaction (PubMedID 24768539)
0

Data Source:
BioGRID (affinity chromatography technology, pull down)

		CORO7	EPS15
Description		coronin 7	epidermal growth factor receptor pathway substrate 15
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Membrane Cytoplasmic Vesicle	Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Clathrin-coated Pit Basal Plasma Membrane Membrane Aggresome Apical Plasma Membrane AP-2 Adaptor Complex Clathrin Coat Of Coated Pit Clathrin-coated Vesicle Early Endosome Membrane Synapse Ciliary Membrane Postsynaptic Endocytic Zone Glutamatergic Synapse
	Molecular Function	Actin Binding Protein Binding	Calcium Ion Binding Protein Binding SH3 Domain Binding Protein-macromolecule Adaptor Activity Polyubiquitin Modification-dependent Protein Binding Identical Protein Binding Ubiquitin Binding Cadherin Binding Metal Ion Binding
	Biological Process	Golgi To Endosome Transport Actin Filament Organization Golgi Organization Protein Transport Cell Migration Establishment Of Cell Polarity Actin Filament Polymerization Positive Regulation Of Hippo Signaling	Positive Regulation Of Receptor Recycling Golgi To Endosome Transport Endocytosis Protein Transport Vesicle Organization Endosomal Transport Receptor-mediated Endocytosis Of Virus By Host Cell Endocytic Recycling Regulation Of Protein Localization Regulation Of Cell Population Proliferation Symbiont Entry Into Host Cell Clathrin Coat Assembly Ubiquitin-dependent Endocytosis Postsynaptic Neurotransmitter Receptor Internalization
Pathways			EGFR downregulation Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis InlB-mediated entry of Listeria monocytogenes into host cell Degradation of CDH1
Drugs
Diseases
GWAS		A body shape index ( 34021172) Eosinophil count ( 32888494) Erectile dysfunction ( 30583798) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 25673412 34021172) Lymphocyte count ( 32888494) Schizophrenia ( 28991256) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 30389748 34021172) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)	Blood urea nitrogen levels ( 31152163) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hip circumference adjusted for BMI ( 34021172) IgE grass sensitization ( 22036096) PR interval ( 30046033 32439900)
Interacting Genes		9 interacting genes: ACTB AP1M1 AP2M1 EPS15 KLHL20 SRC TOB1 WASL ZRANB1	62 interacting genes: AGFG1 AGFG2 AP1G1 AP2A1 AP2A2 CDC40 CLINT1 CORO7 CRK DLGAP5 DNM1 DNM2 DRAM1 EGFR ELF3 EPN1 EPN2 FCHO2 GRB2 HGS ITSN1 LAPTM5 LMTK3 MAPK14 MLLT10 MLLT6 MOB4 MTNR1A NAGPA NEDD4 NUMB NUMBL PALMD PICALM PRKN REPS2 RNF11 RNF26 SCAMP1 SH3BP4 SNAP91 SPART SPATA31E1 SPOPL STAM2 STAMBP STON2 SYNJ1 TC2N TFAP2A TMEM114 UBB UBC UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2H UBQLN1 UBQLN3 USP8 WEE1
Entrez ID		79585	2060
HPRD ID		07975	08968
Ensembl ID		ENSG00000262246	ENSG00000085832
Uniprot IDs		P57737	A0A994J5A3 A0A994J5J3 B7Z240 P42566
PDB IDs			1C07 1EH2 1F8H 1FF1 2IV9 2JXC 4RH5 4RH9 4RHG 4S0G 5AWT 5AWU 5JP2
Enriched GO Terms of Interacting Partners?		Organelle Organization Postsynaptic Neurotransmitter Receptor Internalization Regulation Of Endocytosis Vesicle Organization AP-2 Adaptor Complex Clathrin Adaptor Complex Golgi To Endosome Transport Cellular Component Assembly Clathrin Adaptor Activity Regulation Of Protein Localization Cytoskeleton Organization Regulation Of Synaptic Vesicle Endocytosis Regulation Of Synaptic Vesicle Recycling Regulation Of Vesicle-mediated Transport Glutamatergic Synapse Vesicle Budding From Membrane Intracellular Transport Polyubiquitin Modification-dependent Protein Binding Actin Cytoskeleton Positive Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Cytosol Receptor Internalization Cellular Localization Clathrin-coated Pit Establishment Of Localization In Cell Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Type II Interferon Binding Endocytic Vesicle Membrane Actin Cytoskeleton Organization Clathrin-coated Vesicle Synapse Actin Filament Actin Filament-based Process Intracellular Protein Localization Regulation Of Norepinephrine Uptake Vesicle-mediated Transport In Synapse Negative Regulation Of Membrane Tubulation Protein K33-linked Ubiquitination Protein Deubiquitination Post-Golgi Vesicle-mediated Transport Transporter Regulator Activity Protein Transport Positive Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Positive Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Regulation Of Protein Localization To Plasma Membrane Symbiont Entry Into Host Cell Protein Modification By Small Protein Removal	Endocytosis Clathrin-coated Pit Import Into Cell Clathrin-coated Vesicle Receptor-mediated Endocytosis Vesicle-mediated Transport Clathrin-dependent Endocytosis Synaptic Vesicle Endocytosis Presynaptic Endocytosis Receptor Internalization Clathrin Coat Assembly Modification-dependent Protein Catabolic Process Vesicle Organization Vesicle-mediated Transport In Synapse Establishment Of Localization In Cell Endosome Vesicle Budding From Membrane Proteolysis Involved In Protein Catabolic Process Ubiquitin Conjugating Enzyme Activity Clathrin Binding Cytoplasmic Vesicle Clathrin Adaptor Activity Membrane Organization Cytosol Intracellular Vesicle Ubiquitin-dependent Protein Catabolic Process Protein Localization To Vacuole Post-translational Protein Modification Protein Ubiquitination Post-Golgi Vesicle-mediated Transport Protein Localization To Lysosome Vacuolar Transport Protein K48-linked Ubiquitination Establishment Of Protein Localization To Vacuole Membrane Coat Macromolecule Catabolic Process Clathrin Vesicle Coat Proteolysis Protein Targeting To Lysosome Cellular Localization Lysosomal Transport Negative Regulation Of Cellular Response To Growth Factor Stimulus Protein Modification By Small Protein Conjugation AP-2 Adaptor Complex Endocytic Vesicle Membrane Phosphatidylinositol-4,5-bisphosphate Binding Protein Polyubiquitination Synaptic Vesicle Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Catabolic Process
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