NKAP and FAM124A

Number of citations: 0 (PubMedID 16189514)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		NKAP	FAM124A
Name		NFKB activating protein	family with sequence similarity 124 member A
Structure			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	None
	Molecular Function	Chromatin Binding RNA Binding Protein Binding Chromatin DNA Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Notch Signaling Pathway Hemopoiesis Granulocyte Differentiation T Cell Differentiation In Thymus Somatic Stem Cell Population Maintenance Negative Regulation Of DNA-templated Transcription Positive Regulation Of Alpha-beta T Cell Differentiation Hematopoietic Stem Cell Proliferation	None
Pathways		mRNA Splicing - Major Pathway	None
GWAS		No GWAS studies recorded	Cerebral amyloid angiopathy x sex interaction in Alzheimer’s disease ( 34020725 ) Cerebrospinal fluid clusterin levels ( 26545630 ) Lipoprotein (a) levels ( 30108283 ) Metabolite levels ( 23823483 ) Placental abruption ( 29884306 ) Refractive error ( 32231278 ) Rheumatoid arthritis (ACPA-negative) ( 24532677 )
Interacting Genes		17 interacting genes: AP1M1 CEP70 DHX15 FAM124A FRA10AC1 LUC7L2 OGT PCBP2 PRPF3 PRPF40A RBM39 RBMX2 SRPK1 SRPK2 THAP1 TTC14 U2AF1	30 interacting genes: BEND7 CCDC33 CEP70 CGGBP1 DOCK8 FOXP2 IHO1 IL16 INO80E KIFC3 LNX1 NCK2 NKAP PHC2 PRKG1 RAB3IP RBM10 ROCK1 SAXO1 SRPK1 STAC3 THAP1 TLE5 TRIM41 TRIM54 ZBTB44 ZFP64 ZNF165 ZNF250 ZZZ3
Entrez ID		79576	220108
HPRD ID		06666	08704
Ensembl ID		ENSG00000101882	ENSG00000150510
Uniprot IDs		Q8N5F7	Q86V42
PDB IDs		6QDV 7W5B 8C6J 9FMD	Not available
GO Terms Enriched among Interactors		RNA Splicing MRNA Metabolic Process MRNA Processing Nuclear Speck RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing, Via Transesterification Reactions RNA Binding Nucleic Acid Metabolic Process Protein-RNA Complex Assembly Nucleobase-containing Compound Metabolic Process Nucleic Acid Binding Spliceosomal Complex Assembly RS Domain Binding Spliceosomal Complex Nucleoplasm U2-type Prespliceosome U1 SnRNP Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Macromolecule Metabolic Process Positive Regulation Of Viral Genome Replication Regulation Of RNA Splicing Protein-containing Complex Assembly Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Nucleus Negative Regulation Of Viral Genome Replication Cellular Component Assembly U2-type Precatalytic Spliceosome Positive Regulation Of Viral Process Protein-containing Complex Organization Cajal Body Negative Regulation Of Viral Process Regulation Of Viral Genome Replication U2-type Post-mRNA Release Spliceosomal Complex Protein O-acetylglucosaminyltransferase Activity Innate Immune Response Regulation Of MRNA Metabolic Process Nuclear Speck Organization	Identical Protein Binding Zinc Ion Binding