NKAP and PCBP2

Number of citations of the paper that reports this interaction (PubMedID 22365833)
0

Data Source:
BioGRID (two hybrid)

		NKAP	PCBP2
Description		NFKB activating protein	poly(rC) binding protein 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Nucleus Nucleoplasm Cytoplasm Cytosol Focal Adhesion Membrane Extracellular Exosome Ribonucleoprotein Complex
	Molecular Function	Chromatin Binding RNA Binding Protein Binding Chromatin DNA Binding	Nucleic Acid Binding DNA Binding Single-stranded DNA Binding RNA Binding MRNA Binding Protein Binding Enzyme Binding Ubiquitin Protein Ligase Binding LncRNA Binding Promoter-enhancer Loop Anchoring Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Notch Signaling Pathway Hemopoiesis Granulocyte Differentiation T Cell Differentiation In Thymus Somatic Stem Cell Population Maintenance Negative Regulation Of DNA-templated Transcription Positive Regulation Of Alpha-beta T Cell Differentiation Hematopoietic Stem Cell Proliferation	Immune System Process Regulation Of Transcription By RNA Polymerase II MRNA Metabolic Process Viral RNA Genome Replication Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Innate Immune Response Negative Regulation Of Defense Response To Virus Defense Response To Virus IRES-dependent Viral Translational Initiation Chromatin Looping CGAS/STING Signaling Pathway Negative Regulation Of CGAS/STING Signaling Pathway
Pathways		mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA Negative regulators of DDX58/IFIH1 signaling SARS-CoV-1 activates/modulates innate immune responses
Drugs
Diseases
GWAS			Granulocyte percentage of myeloid white cells ( 27863252) Monocyte percentage of white cells ( 27863252) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		17 interacting genes: AP1M1 CEP70 DHX15 FAM124A FRA10AC1 LUC7L2 OGT PCBP2 PRPF3 PRPF40A RBM39 RBMX2 SRPK1 SRPK2 THAP1 TTC14 U2AF1	45 interacting genes: APOBEC3C BARD1 CASK CEBPA CNBP FLNA FOXP1 FTH1 GAR1 HMGA1 HMGA2 HNRNPD HNRNPK HNRNPL HNRNPR LINC01554 MECOM NKAP OGT PABPC1 PAXIP1 PCBP1 PDIA3 PRPF40A PTBP1 PTBP2 QKI RALYL RBFOX2 RBMX RBPMS SF3B2 SLC7A11 SLU7 SNRPA SRSF3 SRSF7 SUMO2 UBC UTP25 WDR77 WDR83 YBX1 YBX2 YBX3
Entrez ID		79576	5094
HPRD ID		06666	03129
Ensembl ID		ENSG00000101882	ENSG00000197111
Uniprot IDs		Q8N5F7	A0A384N6B9 Q15366
PDB IDs		6QDV 7W5B 8C6J 9FMD	2AXY 2JZX 2P2R 2PQU 2PY9
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Metabolic Process MRNA Processing Nuclear Speck RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing, Via Transesterification Reactions RNA Binding Nucleic Acid Metabolic Process Protein-RNA Complex Assembly Nucleobase-containing Compound Metabolic Process Nucleic Acid Binding Spliceosomal Complex Assembly RS Domain Binding Spliceosomal Complex Nucleoplasm U2-type Prespliceosome U1 SnRNP Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Macromolecule Metabolic Process Positive Regulation Of Viral Genome Replication Regulation Of RNA Splicing Protein-containing Complex Assembly Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Nucleus Negative Regulation Of Viral Genome Replication Cellular Component Assembly U2-type Precatalytic Spliceosome Positive Regulation Of Viral Process Protein-containing Complex Organization Cajal Body Negative Regulation Of Viral Process Regulation Of Viral Genome Replication U2-type Post-mRNA Release Spliceosomal Complex Protein O-acetylglucosaminyltransferase Activity Innate Immune Response Regulation Of MRNA Metabolic Process Nuclear Speck Organization	RNA Binding Nucleic Acid Binding MRNA Binding Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process RNA Splicing MRNA Processing RNA Processing Nucleus Regulation Of MRNA Metabolic Process MRNA Metabolic Process Regulation Of MRNA Processing Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Metabolic Process Regulation Of RNA Splicing Negative Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome Macromolecule Metabolic Process Nucleoplasm RNA Splicing, Via Transesterification Reactions Regulation Of RNA Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Cytoplasmic Translation Spliceosomal Complex Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression Catalytic Step 2 Spliceosome Negative Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Splicing Regulation Of Primary Metabolic Process Negative Regulation Of Metabolic Process Regulation Of DNA-templated Transcription Regulation Of Cytoplasmic Translation Ribonucleoprotein Complex Positive Regulation Of RNA Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?